2,110 research outputs found
On a common circle: natural scenes and Gestalt rules
To understand how the human visual system analyzes images, it is essential to
know the structure of the visual environment. In particular, natural images
display consistent statistical properties that distinguish them from random
luminance distributions. We have studied the geometric regularities of oriented
elements (edges or line segments) present in an ensemble of visual scenes,
asking how much information the presence of a segment in a particular location
of the visual scene carries about the presence of a second segment at different
relative positions and orientations. We observed strong long-range correlations
in the distribution of oriented segments that extend over the whole visual
field. We further show that a very simple geometric rule, cocircularity,
predicts the arrangement of segments in natural scenes, and that different
geometrical arrangements show relevant differences in their scaling properties.
Our results show similarities to geometric features of previous physiological
and psychophysical studies. We discuss the implications of these findings for
theories of early vision.Comment: 3 figures, 2 large figures not include
Evaluation of relationship between middle cerebellar peduncle asymmetry and dominant hand by diffusion tensor imaging
Background: The aim of the study was to evaluate middle cerebellar peduncle (MCP) asymmetry by diffusion tensor imaging (DTI) according to the dominant hand.
Materials and methods: Sixty-four volunteers who met the exclusion and inclusion criteria were prospectively evaluated by DTI. Circular voxels of interest were drawn at the right and left MCP levels for all volunteers. The software automatically calculated the median values of fractional anisotropy (FA), mean diffusivity (MD), and number of fibres (NF). The volunteers were categorised as the right-handed (n = 44) and left-handed (n = 20) groups using the Dellatolas test. The mean values of FA, MD and NF were statistically compared between the two sides and
the two groups.
Results: In both groups, the mean value of FA for the right MCP was significantly higher than the left MCP (p = 0.0016 and p = 0.0032 for the right- and left-handed groups, respectively). In both groups, no significant difference was observed between the right and left MCPs in terms of MD and NF (p = 0.75, p = 0.69 and p = 0.96, p = 0.46, respectively). There was also no statistically significant difference between the groups for the mean values of FA, MD and NF of each MCP (p = 0.74, p = 0.26 and p = 0.26, respectively for the right MCP and p = 0.78, p = 0.37 and p = 0.54, respectively for the left MCP).
Conclusions: There is an asymmetry between the mean FA values of the right and left MCP. However, this asymmetry is independent of the dominant hand
Stationary State Solutions of a Bond Diluted Kinetic Ising Model: An Effective-Field Theory Analysis
We have examined the stationary state solutions of a bond diluted kinetic
Ising model under a time dependent oscillating magnetic field within the
effective-field theory (EFT) for a honeycomb lattice . Time evolution of
the system has been modeled with a formalism of master equation. The effects of
the bond dilution, as well as the frequency and amplitude of
the external field on the dynamic phase diagrams have been discussed in detail.
We have found that the system exhibits the first order phase transition with a
dynamic tricritical point (DTCP) at low temperature and high amplitude regions,
in contrast to the previously published results for the pure case \cite{Ling}.
Bond dilution process on the kinetic Ising model gives rise to a number of
interesting and unusual phenomena such as reentrant phenomena and has a
tendency to destruct the first-order transitions and the DTCP. Moreover, we
have investigated the variation of the bond percolation threshold as functions
of the amplitude and frequency of the oscillating field.Comment: 8 pages, 4 figure
Turner syndrome and associated problems in turkish children: A multicenter study
Objective: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls. This study aimed to systematically investigate the key clinical features of TS in relationship to karyotype in a large pediatric Turkish patient population. Methods: Our retrospective study included 842 karyotype-proven TS patients aged 0-18 years who were evaluated in 35 different centers in Turkey in the years 2013-2014. Results: The most common karyotype was 45,X (50.7%), followed by 45,X/46,XX (10.8%), 46,X,i(Xq) (10.1%) and 45,X/46,X,i(Xq) (9.5%). Mean age at diagnosis was 10.2±4.4 years. The most common presenting complaints were short stature and delayed puberty. Among patients diagnosed before age one year, the ratio of karyotype 45,X was significantly higher than that of other karyotype groups. Cardiac defects (bicuspid aortic valve, coarctation of the aorta and aortic stenosi) were the most common congenital anomalies, occurring in 25% of the TS cases. This was followed by urinary system anomalies (horseshoe kidney, double collector duct system and renal rotation) detected in 16.3%. Hashimoto’s thyroiditis was found in 11.1% of patients, gastrointestinal abnormalities in 8.9%, ear nose and throat problems in 22.6%, dermatologic problems in 21.8% and osteoporosis in 15.3%. Learning difficulties and/or psychosocial problems were encountered in 39.1%. Insulin resistance and impaired fasting glucose were detected in 3.4% and 2.2%, respectively. Dyslipidemia prevalence was 11.4%. Conclusion: This comprehensive study systematically evaluated the largest group of karyotype-proven TS girls to date. The karyotype distribution, congenital anomaly and comorbidity profile closely parallel that from other countries and support the need for close medical surveillance of these complex patients throughout their lifespan. © Journal of Clinical Research in Pediatric Endocrinology
Structure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15.
The crystal structure of a putative NTPase, YP_001813558.1 from Exiguobacterium sibiricum 255-15 (PF09934, DUF2166) was determined to 1.78 Å resolution. YP_001813558.1 and its homologs (dimeric dUTPases, MazG proteins and HisE-encoded phosphoribosyl ATP pyrophosphohydrolases) form a superfamily of all-α-helical NTP pyrophosphatases. In dimeric dUTPase-like proteins, a central four-helix bundle forms the active site. However, in YP_001813558.1, an unexpected intertwined swapping of two of the helices that compose the conserved helix bundle results in a `linked dimer' that has not previously been observed for this family. Interestingly, despite this novel mode of dimerization, the metal-binding site for divalent cations, such as magnesium, that are essential for NTPase activity is still conserved. Furthermore, the active-site residues that are involved in sugar binding of the NTPs are also conserved when compared with other α-helical NTPases, but those that recognize the nucleotide bases are not conserved, suggesting a different substrate specificity
Low level constraints on dynamic contour path integration
Contour integration is a fundamental visual process. The constraints on integrating
discrete contour elements and the associated neural mechanisms have typically been
investigated using static contour paths. However, in our dynamic natural environment
objects and scenes vary over space and time. With the aim of investigating the
parameters affecting spatiotemporal contour path integration, we measured human
contrast detection performance of a briefly presented foveal target embedded in
dynamic collinear stimulus sequences (comprising five short 'predictor' bars appearing
consecutively towards the fovea, followed by the 'target' bar) in four experiments. The
data showed that participants' target detection performance was relatively unchanged
when individual contour elements were separated by up to 2° spatial gap or 200ms
temporal gap. Randomising the luminance contrast or colour of the predictors, on the
other hand, had similar detrimental effect on grouping dynamic contour path and
subsequent target detection performance. Randomising the orientation of the
predictors reduced target detection performance greater than introducing misalignment
relative to the contour path. The results suggest that the visual system integrates
dynamic path elements to bias target detection even when the continuity of path is
disrupted in terms of spatial (2°), temporal (200ms), colour (over 10 colours) and
luminance (-25% to 25%) information. We discuss how the findings can be largely
reconciled within the functioning of V1 horizontal connections
Spreading continents kick-started plate tectonics
International audienceStresses acting on cold, thick and negatively buoyant oceanic litho- sphere are thought to be crucial to the initiation of subduction and the operation of plate tectonics, which characterizes the present- day geodynamics of the Earth. Because the Earth’s interior was hotter in the Archaean eon, the oceanic crust may have been thicker, thereby making the oceanic lithosphere more buoyant than at present, and whether subduction and plate tectonics occurred during this time is ambiguous, both in the geological record and in geodynamic models. Here we show that because the oceanic crust was thick and buoyant5, early continents may have produced intra-lithospheric gravitational stresses large enough to drive their gravitational spreading, to initiate subduction at their margins and to trigger episodes of subduction. Our model predicts the co-occurrence of deep to progressively shallower mafic volcanics and arc magmatism within continents in a self-consistent geodynamic framework, explaining the enigmatic multimodal volcanism and tectonic record of Archaean cratons. Moreover, our model predicts a petrological stratification and tectonic structure of the sub-continental lithospheric mantle, two predictions that are consistent with xenolith and seismic studies, respectively, and consistent with the existence of a mid-lithospheric seismic discontinuity. The slow gravitational collapse of early continents could have kick-started transient episodes of plate tectonics until, as the Earth’s interior cooled and oceanic lithosphere became heavier, plate tectonics became self-sustaining
The determination of the pituitary gland, optic chiasm, and intercavernous distance measurements in healthy subjects according to age and gender
Background: This paper was undertaken to determine the morphometry of pituitary gland diameter, pituitary gland height, intercavernous distance, optic chiasm diameter and optic chiasm height in skulls of Turkish population aged between 18 and 60 years. Materials and methods: It was a retrospective study in which 292 subjects were included 187 females and 105 males, ranging from 18 up to 60 years. Subjects underwent brain magnetic resonance imaging in the Radiology Department. Statistical analysis was performed with SPSS 21.00 programme. ANOVA test, χ2 test, and Pearson correlation analysis were used to determine the relation and significance between measurements and age group. The p < 0.05 value was considered as significant. Results: The groups were divided into five groups according to age. The overall means and standard deviations of the measurements were: pituitary gland width, 13.09 ± 1.99 mm; pituitary gland height, 4.91 ± 1.10 mm; intercavernous distance, 15.93 ± 3.05 mm; optic chiasm width, 12.82 ± 1.27 mm; and optic chiasm height, 2.80 ± 0.49 mm in females, respectively whereas, the same measurements were 12.96 ± 1.74 mm; 4.79 ± 0.95 mm; 16.08 ± 3.11 mm; 13.13 ± 1.37 mm; 2.86 ± 0.70 mm in males, respectively. Height of the pituitary gland reached a maximum in the age group of 18 to 20 years in both females and males and there was a decrease in the pituitary gland height in the subsequent age groups. Conclusions: Knowledge of the variation in the size of pituitary gland, intercavernous distance and optic chiasm is important to evaluate the dimensions of these structures for clinical and pathological processes
Suitability of foramen magnum measurements in sex determination and their clinical significance
Background: The foramen magnum provides a transition between fossa cranii posterior and canalis vertebralis. Medulla oblongata, arteria vertebralis and nervus accessorius spinal part pass through the foramen magnum. In this study, we aimed to make the morphometric measurements of the foramen magnum on computed tomography (CT) and to determine the feasibility of sex determination based on these measurements. Besides sex determination, from a clinical aspect, it is important to know the measurements of the foramen magnum in the normal population in terms of diseases characterised by displacement of the posterior fossa structures through foramen magnum to upper cervical spinal canal such as Chiari malformations and syringomyelia.
Materials and methods: All the data for our study was obtained retrospectively from 100 patients (50 males, 50 females) who had a CT scan of the head and neck region in Adnan Menderes University Hospital, Department of Radiology. To examine the foramen magnum in each and every occipital bone, we measured the foramen magnum’s anteroposterior diameter, transverse diameter, the area of the foramen magnum and its circumference.
Results: We found that men have a higher average value than women in our study. According to Student’s t-test results; in all measured parameters, there is significant difference between the genders (p < 0.05). When multivariate discriminant function test is performed for all four measurements, the discrimination rate is 64% for all women, 70% for all men and 67% for both genders.
Conclusions: As a result of our study, the metric data we obtained will be useful in cases where the skeletons’ sex could not be determined by any other methods. We believe that, our study may be useful for other studies in determining of sex from foramen magnum. Our measurements could give some information of the normal ranges of the foramen magnum in normal population, so that this can contribute to the diagnosis process of some diseases by imaging. (Folia Morphol 2018; 77, 1: 99–104)
An investigation of micronucleus induction by butylated hydroxytoluene in wistar rat bone marrow cells
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