Erreurs médicamenteuses: comment les prévenir en soins aigus lors du transfert d'un patient ? : revue de littérature

Bon nombre d’erreurs médicamenteuses sont rencontrées lors des phases de transfert des patients. En Suisse, l’enquête de l’Opsendal San Giovani à Bellinzone démontre que 40% des personnes hospitalisées en 2006 avaient des dossiers contenant des erreurs dans la documentation des médicaments. 50% des changements liés à la médication ne sont pas documentés dans les lettres de sortie

"C'est assez" : programme de détection et d'orientation des adultes concernés par la violence : origines et développements 2000-2004

[Table des matières] Résumé. 1. La violence, un problème de santé publique ? 1.1. Quelques jalons historiques récents. 1.2. Définitions et typologie. 1.3. Données épidémiologiques suisses. 1.4. Conséquences sanitaires et sociales. 1.5. Possibilité d'intervention. 2. Origine du projet. 2.1. Résumé de l'étude " Violence conjugale dans le canton de Vaud". 2.2. Contexte politique et institutionnel de démarrage du projet. 3. Initiation du projet. 3.1. Aspects organisationnels. 3.2. Travaux préparatoires. 4. Développements en 2002-2004. 4.1. Axe quantitatif. 4.2. Axe qualitatif. 4.3. Protocole d'intervention. 4.4. Carte du réseau. 4.5. Formation des professionnels. 4.6. Permanence de soutien et d'orientation. 5. Conclusions. 5.1. Les opportunités et les difficultés. 5.2 Plan de développement 2004-2007. 5.3. Recherches à mener. 6. Annexes

Les facteurs influençant l'adhésion au régime hyposodé chez les personnes atteintes d'une insuffisance cardiaque: une revue de littérature étoffée

l’insuffisance cardiaque touche environ 150'000 personnes en Suisse (Fondation Suisse de Cardiologie, n.d.). En plus du traitement médicamenteux, le régime hyposodé est une composante essentielle de la prise en charge de l’insuffisance cardiaque. Cependant, un manque d’adhésion au programme médical est la raison la plus commune pour une réadmission à l’hôpital dans 41% des cas (Colucci, 2014)

Global conservation status assessment of the threatened aquatic plant genus Baldellia (Alismataceae): challenges and limitations

In this study, the aquatic monocot Baldellia (Alismataceae) is used as a model for evaluating the general hindrances and shortfalls in the global conservation status assessment of a threatened taxon. Our study clearly shows that Linnean shortfalls (uncertainty in the number of species and taxonomy) and the Wallacean shortfall (fragmentary knowledge regarding distribution) form the basis for all other hindrances. We demonstrate that even in Europe, which has traditionally been very well investigated, between 60 and 75% of regions or countries possess no detailed distribution maps and/or data banks for Baldellia spp. Furthermore, between 50 and 60% of regions do not have any published red list category. Thus, only general conclusions concerning the global conservation status of the three Baldellia taxa are possible—a global assessment of conservation status for B. ranunculoides subsp. repens is nearly impossible. Baldellia ranunculoides s.str. shows a strong decline in practically all regions of its natural range, and thus it is probably the most threatened species in the genus. Baldellia alpestris is the least threatened species in the genus, even though it is a narrow endemic. Our case study clearly shows the need for reinforced coordination of research and conservation activities as well as an urgent need for data accessibility regarding taxonomic, chorological and conservation studies of endangered specie

Anti-apolipoprotein A-1 IgG as an independent cardiovascular prognostic marker affecting basal heart rate in myocardial infarction

Aims To assess the prognostic value of anti-apolipoprotein A-1 (anti-apoA-1) IgG after myocardial infarction (MI) and its association with major cardiovascular events (MACEs) at 12 months and to determine their association with resting heart rate (RHR), a well-established prognostic feature after MI. Anti-apoA-1 IgG have been reported in MI without autoimmune disease, but their clinical significance remains undetermined. Methods and results A total of 221 consecutive patients with MI were prospectively included, and all completed a 12-month follow-up. Major cardiovascular events consisted in death, MI, stroke, or hospitalization either for an acute coronary syndrome or heart failure. Resting heart rate was obtained on Holter the day before discharge under the same medical treatment. Neonate rat ventricular cardiomyocytes (NRVC) were used in vitro to assess the direct anti-apoA-1 IgG effect on RHR. During follow-up, 13% of patients presented a MACE. Anti-apoA-1 IgG positivity was 9% and was associated with a higher RHR (P = 0.0005) and higher MACE rate (adjusted OR, 4.3; 95% CI, 1.46-12.6; P = 0.007). Survival models confirmed the significant nature of this association. Patients with MACE had higher median anti-apoA-1 IgG values at admission than patients without (P = 0.007). On NRVC, plasma from MI patients and monoclonal anti-apoA-1 IgG induced an aldosterone and dose-dependent positive chronotropic effect, abrogated by apoA-1 and therapeutic immunoglobulin (IVIG) pre-incubation. Conclusions In MI patients, anti-apoA-1 IgG is independently associated with MACE at 1-year, interfering with a currently unknown aldosterone-dependent RHR determinant. Knowing whether anti-apoA-1 IgG assessment could be of interest to identify an MI patient subset susceptible to benefit from apoA-1/IVIG therapy remains to be demonstrate

Study of the B +→ J / ψ Λ ¯ p decay in proton-proton collisions at √s = 8 TeV

A study of the B +→ J / ψ Λ ¯ p decay using proton-proton collision data collected at s = 8 TeV by the CMS experiment at the LHC, corresponding to an integrated luminosity of 19.6 fb−1, is presented. The ratio of branching fractions B(B+→J/ψΛ¯p)/B(B+→J/ψK∗(892)+) is measured to be (1.054 ± 0.057(stat) ± 0.035(syst) ± 0.011(B))%, where the last uncertainty reflects the uncertainties in the world-average branching fractions of Λ ¯ and K*(892) + decays to reconstructed final states. The invariant mass distributions of the J / ψ Λ ¯ , J/ψp, and Λ ¯ p systems produced in the B +→ J / ψ Λ¯ p decay are investigated and found to be inconsistent with the pure phase space hypothesis. The analysis is extended by using a model-independent angular amplitude analysis, which shows that the observed invariant mass distributions are consistent with the contributions from excited kaons decaying to the Λ ¯ p system. [Figure not available: see fulltext.