Metaplasia ossea diagnosticata su leiomioma uterino

Riportiamo un caso di metaplasia ossea in un leiomioma uterino scoperto casualmente in una donna di 53 anni operata di isterectomia totale per una neoformazione annessial

Evaluate the adaptability of present licensing requirements to new nuclear fuels for use in current reactors

Currently there is no comprehensive plan available for the methodology, timeline, and cost structure needed when licensing for new nuclear fuels, cladding, and geometry. By combining various sources from the NRC, nuclear vendor documents, and experience from engineers who have worked on licensing standard nuclear materials, a methodology, timeline, and cost structure for licensing new fuels, cladding, and geometry was developed. The specific scenarios of fuels, cladding, and geometry were used to outline the common advantages and disadvantages of changing the physical properties or physical structure of the standard nuclear fuel assembly. From these changes, the timeline and costing analyses were performed. It was determined from the timeline and costing analyses that the most advantageous development scenario was to combine the fuel and cladding licensing together and license the fuel/cladding combination for over 100 Gigawatt-days per metric ton of uranium

Does the professional learning community intermediate the effects of principal's leadership on teaching innovation?

This study explores the intricate dynamics of leadership, professional learning communities (PLCs), and their collective impact on driving teaching innovation. We analyze an original dataset from 352 schools from five Italian regions by combining two original datasets from a principals’ questionnaire and innovative didactic project information for each school. We use structural equation modeling to analyze factors influencing innovation. Our results reveal a significant and positive influence of both supportive and instructional leadership styles on the organizational capabilities of the PLC, indirectly affecting teaching innovation. Interestingly, while organizational capabilities exhibited a strong positive relationship with teaching innovation, personal and interpersonal capabilities do not show a significant relationship. This suggests that these aspects of PLC alone may not suffice in driving pedagogical innovation. Overall, this paper underlines the importance of effective leadership and robust PLCs in fostering an environment conducive to innovative teaching practices. It offers valuable insights for policymakers, educators, and school leaders aiming to cultivate a culture of pedagogical innovation in their institutions

Relationship Between Left Ventricular Mass and Exercising Systolic Blood Pressure in Women

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Hybrid two stage flowshop scheduling with secondary resources based on time buckets

Spanish Ministry of Economy, Industry and Competitiveness; European Regional Development Fund (ERDF) [DPI2017-85343-P

Concept of a Maneuvering Load Control System and Effect on the Fatigue Life Extension

Abstract This paper presents a methodology for the conceptual design of a Maneuver Load Control system taking into account the airframe flexibility. The system, when switched on, is able to minimize the bending moment augmentation at a wing station near the wing root during an unsteady longitudinal maneuver. The reduction of the incremental wing bending moment due to maneuvers can lead to benefits such as improved pay-loads/gross weight capabilities and/or extended structural fatigue life. The maneuver is performed by following a desired vertical load factor law with elevators deflections, starting from the trim equilibrium in level flight. The system observes load factor and structural bending through accelerometers and calibrated strain sensors and then sends signals to a computer that symmetrically actuates ailerons for reducing the structural bending and elevators for compensating the perturbation to the longitudinal equilibrium. The major limit of this kind of systems appears when it has to be installed on commercial transport aircraft for reduced OEW or augmented wing aspect-ratio. In this case extensive RAMS analyses and high redundancy of the MLC related sub-systems are required by the Certification Authority. Otherwise the structural design must be performed at system off. Thus the unique actual benefit to be gained from the adoption of a MLC system on a commercial transport is the fatigue life extension. An application to a business aircraft responding to the EASA Certification Specifications, Part 25, has been performed. The aircraft used for the numerical application is considered only as a test case-study. Most of design and analysis considerations are applicable also to other aircraft, such as unmanned or military ones, although some design requirements can be clearly different. The estimation of the fatigue life extension of a structural joint (wing lower skin-stringer), located close to the wing root, has been estimated by showing the expected benefit to be gained from the adoption of such a maneuvering load control system

The Genome Sequence of Leishmania (Leishmania) amazonensis: Functional Annotation and Extended Analysis of Gene Models

We present the sequencing and annotation of the Leishmania (Leishmania) amazonensis genome, an etiological agent of human cutaneous leishmaniasis in the Amazon region of Brazil. L. (L.) amazonensis shares features with Leishmania (L.) mexicana but also exhibits unique characteristics regarding geographical distribution and clinical manifestations of cutaneous lesions (e.g. borderline disseminated cutaneous leishmaniasis). Predicted genes were scored for orthologous gene families and conserved domains in comparison with other human pathogenic Leishmania spp. Carboxypeptidase, aminotransferase, and 3'-nucleotidase genes and ATPase, thioredoxin, and chaperone-related domains were represented more abundantly in L. (L.) amazonensis and L. (L.) mexicana species. Phylogenetic analysis revealed that these two species share groups of amastin surface proteins unique to the genus that could be related to specific features of disease outcomes and host cell interactions. Additionally, we describe a hypothetical hybrid interactome of potentially secreted L. (L.) amazonensis proteins and host proteins under the assumption that parasite factors mimic their mammalian counterparts. the model predicts an interaction between an L. (L.) amazonensis heat-shock protein and mammalian Toll-like receptor 9, which is implicated in important immune responses such as cytokine and nitric oxide production. the analysis presented here represents valuable information for future studies of leishmaniasis pathogenicity and treatment.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Universidade Federal de São Paulo, EPM UNIFESP, Escola Paulista Med, Dept Microbiol Imunol & Parasitol, BR-04023062 São Paulo, BrazilLNBio CNPEM, Lab Nacl Biociencias, Campinas, SP, BrazilLGE UNICAMP, Lab Genom & Expressao, Campinas, SP, BrazilInst Agron Campinas, Ctr Pesquisa & Desenvolvimento Recursos Geneti Ve, Campinas, SP, BrazilUniv Calif San Diego, Sch Med, Dept Pediat, San Diego, CA 92103 USAUniversidade Federal de São Paulo, UNIFESP, Dept Ciencia & Tecnol, Sao Jose Dos Campos, BrazilUniv N Carolina, Sch Med, Dept Genet, Chapel Hill, NC USAUniv Fed Minas Gerais, ICB UFMG, Inst Ciencias Biol, Dept Biol Geral, Belo Horizonte, MG, BrazilUniversidade Federal de São Paulo, EPM UNIFESP, Escola Paulista Med, Dept Microbiol Imunol & Parasitol, BR-04023062 São Paulo, BrazilUniversidade Federal de São Paulo, UNIFESP, Dept Ciencia & Tecnol, Sao Jose Dos Campos, BrazilFAPESP: 07/50551-2FAPESP: 10/19335-4Web of Scienc

Multi-step Multi-camera View Planning for Real-Time Visual Object Tracking

Abstract. We present a new method for planning the optimal next view for a probabilistic visual object tracking task. Our method uses a variable number of cameras, can plan an action sequence several time steps into the future, and allows for real-time usage due to a computation time which is linear both in the number of cameras and the number of time steps. The algorithm can also handle object loss in one, more or all cameras, interdependencies in the camera’s information contribution, and variable action costs. We evaluate our method by comparing it to previous approaches with a prere-corded sequence of real world images. From K. Franke et al., Pattern Recognition, 28th DAGM Symposium, Springer, 2006, (pp. 536–545).