Quantity and Quality of Dairy Product Intake and Their Relationship with Body Composition in Children and Adolescents from Mexico City

Background: The association between milk-derived or dairy product intake (DPI) and the body composition (BC) of children and adolescents continues to be controversial. Objective: This study sought to evaluate the association between the quantity and quality of DPI and the BC of Mexican children and adolescents. Methods: A secondary data analysis of a cross-sectional population-based sample of 2104 children and adolescents (aged 4–18 years) recruited from schools in Mexico City was performed. To assess the association between the quantity and quality of DPI, evaluated by questionnaire, and BC, dual X-ray densitometry (DXA) and surrogate parameters of the fat mass index (FMI) and lean mass index (LMI) were used. The adequacy of the quantity and quality of DPI was classified according to age-specific recommendations and the sugar, sodium and fat contents of the products consumed. Relationships were assessed by means of lineal regressions adjusted for age, sex, physical activity, sleep time and screen hours. Results: We included a total of 1840 participants aged 4.5–18 years, 52% of whom were female. Average daily DPI was 4.0 ± 2.4 servings/day, with a predominance of milk without sugar (42.7% of DPI). The quantity and quality of DPI significantly reduced the FMI (beta = −0.1 kg/m2, 95% CI −0.17 to −0.06, p < 0.001 and beta = −0.17 kg/m2, 95% CI −0.26 to −0.07, p < 0.001). No significant relationships were seen with the LMI. Conclusions: Higher quantities of good-quality DPI are associated with lower adiposity in Mexican children and adolescents

Barreras y acciones para mejorar la calidad y el impacto de Acta Pediátrica de México

Acta Pediátrica de México se publica desde 1980 de manera puntual e ininterrumpida; es el Órgano Oficial del Instituto Nacional de Pediatría. Es una publicación bimestral que tiene como propósito fundamental la difusión de evidencia científica y de información generada como producto de investigación original básica, clínica, epidemiológica y social en el campo de la pediatría, que permita generar y mejorar los modelos de atención a la salud durante la infancia y la adolescencia. Desde 2013, el equipo editorial de la revista se renovó y desde entonces hemos identificado barreras e implementado acciones para lograr mejorar su calidad e impacto

249 Risk Factors Associated to Mortality in Pediatric Patients with Hemophagocytic Lymphohistiocytosis

OBJECTIVE: Identify risk factors associated to mortality in pediatric patients with hemophagocytic lymphohistiocytosis. METHODS: Retrospective cross-sectional study of medical records with discharge diagnosis of Hemophagocytic syndrome/Hemophagocytic lymphohistiocytosis (ICD-10; D76.1/D76.2) from Jan2004-May2011 in a pediatric-tertiary-care-center. Descriptive and risk analysis were made on SPSS Statistics V17.0. RESULTS: Thirty medical records were analyzed. Median-for-age: 2 years 8 months, (range: 2 months-to-15 years). Sex distribution: 14 girls (47%), 16 boys (53%). Median of symptoms duration: 1 month (range: 3 days-to-7 years). Reported symptoms and physical signs at hospital admission: fever n = 28 (93%), asthenia/adynamia n = 11 (37%), skin findings n = 10 (33%), epistaxis n = 5 (17%), gastrointestinal bleeding n = 4 (13%), hepatomegaly n = 27 (90%), splenomegaly n = 21 (70%), lymphadenopathies n = 14 (47%), paleness n = 14 (47%), purpura n = 5 (17%). Laboratory findings: anemia n = 29 (97%), LDH elevation n = 28 (93%), hypoalbuminemia n = 27 (90%), thrombocytopenia n = 26 (87%), hypertransaminasemia n = 25 (83%), haemophagocytosis n = 22 (73%), hypertrigliceridemia n = 21 (70%), hypofibrinogenemia n = 20 (67%), leucopenia n = 19 (63%), hyperferritinemia n = 15(50%). In 18 patients (60%) active infection was evident at hospital admission: pneumonia n = 9(50%), gastroenteritis n = 2 (11%), meningitis n = 1 (5%), others n = 6 (33%). Epstein-Barr virus infection was diagnosed in 7 patients (23%). All patients were treated according to HLH-2004 guidelines. Overall mortality 63% (n = 19), 9(47%) died from septic-shock, 7 (36%) haemorraghic-shock, and 1(5%) with acute liver failure. Differences between non-survivours and survivours by (x(2)): hypofibrinogenemia (53%versus 13%; P = 0.039), epistaxis (17% versus 0%; P = 0.023), evident clinical infection (47%versus 13%; P = 0.044), elevated LDH levels (63% versus 30%; P = 0.039), hemophagocytosis (57% versus 17%; P = 0.024). Risk factors associated to mortality: history of epistaxis (OR = 1.78, 95% CI, 1.26-2.52; P = 0.023), evident clinical infection at hospital admission (OR = 2.41, 95% CI, 1.08-5.8; P = 0.044). Normal levels of LDH showed diminished mortality risk (OR = 0.32, 95%, CI, 0.18-0.55; P = 0.039). CONCLUSIONS: The present study describes the most common clinical, physical and laboratory findings in patients with haemophagocytic lymphohistiocytosis attended in our hospital. We were able to identify risk factors associated to mortality, and 1 protective factor

249 Risk Factors Associated to Mortality in Pediatric Patients with Hemophagocytic Lymphohistiocytosis

We propose a statistical measure for the degree of acceptability of light verb constructions, such as take a walk, based on their linguistic properties. Our measure shows good correlations with human ratings on unseen test data. Moreover, we find that our measure correlates more strongly when the potential complements of the construction (such as walk, stroll, or run) are separated into semantically similar classes. Our analysis demonstrates the systematic nature of the semi-productivity of these constructions

Adolescente femenino con granulomatosis de Wegener fulminante

Adolescente femenino de 13 años de edad, originaria de Guerrero, grupo étnico mixteco, padres analfabetos y con poco entendimiento del español. Sin otros antecedentes de importancia para el padecimiento. Inició un mes previo con la aparición de una pápula hipercrómica en párpado superior derecho que en los 10 días previos al ingreso aumentó de volumen generando proptosis. Al interrogatorio se negó dolor, lagrimeo, fiebre, o pérdida de peso. Ingresó con fiebre (39.0°C), palidez generalizada, proptosis derecha con exposición de córnea y conjuntiva, eritema periorbitario, movimientos oculares y agudeza visual disminuidos (i.e. contaba dedos a 1 m), pupila con tendencia a midriasis, hiperreactividad a la luz, y fondo de ojo con papila hiperémica edematosa y tortuosidad peripapilar. El resto de exploración no mostró datos relevantes. Se hospitalizó para iniciar tratamiento antimicrobiano parenteral de amplio espectro (i.e. ceftriaxona y vancomicina) y abordar proptosis unilateral