419 research outputs found
Léon Marillier and the veridical hallucination in late-nineteenth- and early-twentieth-century French psychology and psychopathology.
Recent research on the professionalization of psychology at the end of the nineteenth century shows how objects of knowledge which appear illegitimate to us today shaped the institutionalization of disciplines. The veridical or telepathic hallucination was one of these objects, constituting a field both of division and exchange between nascent psychology and disciplines known as 'psychic sciences' in France, and 'psychical research' in the Anglo-American context. In France, Leon Marillier (1862-1901) was the main protagonist in discussions concerning the concept of the veridical hallucination, which gave rise to criticisms by mental specialists and psychopathologists. After all, not only were these hallucinations supposed to occur in healthy subjects, but they also failed to correspond to the Esquirolian definition of hallucinations through being corroborated by their representation of external, objective events.Andreas Sommer’s contribution to this article was made possible through support by the Perrott-Warrick Fund, Trinity College, University of Cambridge, and Cedar Creek Institute, Charlottesville, VA.This is the author accepted manuscript. The final version is available from SAGE via http://dx.doi.org/10.1177/0957154X1456275
Dill extract induces elastic fiber neosynthesis and functional improvement in the ascending aorta of aged mice with reversal of age-dependent cardiac hypertrophy and involvement of lysyl oxidase-like-1
Elastic fibers (90% elastin, 10% fibrillin-rich microfibrils) are synthesized only in early life and adolescence mainly by the vascular smooth muscle cells through the cross-linking of its soluble precursor, tropoelastin. Elastic fibers endow the large elastic arteries with resilience and elasticity. Normal vascular aging is associated with arterial remodeling and stiffening, especially due to the end of production and degradation of elastic fibers, leading to altered cardiovascular function. Several pharmacological treatments stimulate the production of elastin and elastic fibers. In particular, dill extract (DE) has been demonstrated to stimulate elastin production in vitro in dermal equivalent models and in skin fibroblasts to increase lysyl oxidase-like-1 (LOXL-1) gene expression, an enzyme contributing to tropoelastin crosslinking and elastin formation. Here, we have investigated the effects of a chronic treatment (three months) of aged male mice with DE (5% or 10
3DSC - A New Dataset of Superconductors Including Crystal Structures
Data-driven methods, in particular machine learning, can help to speed up the
discovery of new materials by finding hidden patterns in existing data and
using them to identify promising candidate materials. In the case of
superconductors, which are a highly interesting but also a complex class of
materials with many relevant applications, the use of data science tools is to
date slowed down by a lack of accessible data. In this work, we present a new
and publicly available superconductivity dataset ('3DSC'), featuring the
critical temperature of superconducting materials additionally
to tested non-superconductors. In contrast to existing databases such as the
SuperCon database which contains information on the chemical composition, the
3DSC is augmented by the approximate three-dimensional crystal structure of
each material. We perform a statistical analysis and machine learning
experiments to show that access to this structural information improves the
prediction of the critical temperature of materials.
Furthermore, we see the 3DSC not as a finished dataset, but we provide ideas
and directions for further research to improve the 3DSC in multiple ways. We
are confident that this database will be useful in applying state-of-the-art
machine learning methods to eventually find new superconductors.Comment: 15 pages + 10 pages of supporting information; UPDATE: standardised
formatting, removed double dash from title & updated github link
Stiffness and thickness of the upper trapezius muscle increase after repeated climbing bouts in male climbers
Background Indoor climbing involves overloading the shoulder girdle, including the rotator cuff and upper trapezius muscles. This on the field study aimed to investigate the effects of repeated climbing bouts on morphological and mechanical measures of the upper trapezius muscle. Materials and Methods Fifteen experienced male climbers participated in the study. Rate of perceived exertion (RPE), blood lactate concentration ([La−]b), and stiffness and thickness over four points of the upper trapezius were assessed before and after a repeated climbing exercise. The procedure for the climbing exercise consisted of five climbs for a total time of 5-minutes per climb, followed by a 5-minute rest. Results The analysis showed an increase from baseline to after the 3rd climb (p ≤ 0.01) for RPE and after the 5th climb for [La−]b (p ≤ 0.001). Muscle stiffness and thickness increased at all points (1–2–3–4) after the 5th climb (p ≤ 0.01). We found spatial heterogeneity in muscle stiffness and thickness; muscle stiffness was the highest at Point 4 (p ≤ 0.01), while muscle thickness reached the highest values at points 1–2 (both p ≤ 0.01). Moreover, the analysis between the dominant and non-dominant shoulder showed greater stiffness after the 1st climb at Point 1 (p = 0.004) and after the 5th climb at Point 4 (p ≤ 0.001). Conclusions For muscle thickness, the analysis showed significant changes in time and location between the dominant and the non-dominant shoulder. Bilateral increases in upper trapezius muscle stiffness and thickness, with simultaneous increases in RPE and blood lactate in response to consecutive climbs eliciting fatigue
Measurement of the W mass in collisions at 183 GeV
The mass of the W boson is obtained from reconstructed invariant mass distributions in W-pair events. The sample of W pairs is selected from 57 pb collected with the ALEPH detector in 1997 at a centre-of-mass energy of 183 GeV. The invariant mass distributions of reweighted Monte Carlo events are fitted separately to the experimental distributions in the and all l\nuqqbar channels to give the following W masses: , where the theory error represents the possible effects of final state interactions. The combination of these two measurements, including the LEP energy calibration uncertainty, gives $m_{W} = 80.393 \pm 0.128(stat.)\pm 0.041(syst.) \pm 0.028(theory)\pm 0.021(LEP) GeV/c^2
Measurement of the tau lepton lifetime with the three-dimensional impact parameter method.
A new method is presented for the measurement of the mean lepton lifetime using events in which 's are pair-produced and both 's decay to hadrons and . Based on the correlation between the two 's produced at a symmetric collider, the 3DIP method relies on the three-dimensional information from a double-sided vertex detector and on kinematic constraints for the precise measurement of the decay angles. Using the data collected from 1992 to 1994 with the ALEPH detector at LEP, a lifetime of \fs is obtained from the sample in which both 's decay to one charged track, and \fs from the sample in which one decays to one prong and the other to three prongs. The results show small statistical correlations with those derived from other methods. When combined with the previously published ALEPH measurements, the resulting lifetime is \fs
Search for supersymmetric particles in collisions at centre-of-mass energies of 130 and 136 GeV
- …
