4,023 research outputs found

    Movement of Spermatozoa in Viscous Environments

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    Observations of the effects of increased viscosity have been important in attempting to understand the mechanical forces and molecular mechanisms involved in cell motility. Berg & Turner (1979) have recently demonstrated that the movement of bacteria at increased viscosities depends on the nature of the macromolecules used to obtain increased viscosities. With methyl cellulose, an unbranched, long-chain polymer, decreases in rotation rates of tethered E. coli were much less than with Ficoll, a highly branched polymer, even though the viscosities measured at the macroscopic level were similar. At the microscopic level, methyl cellulose apparently forms a loose, quasi-rigid network in solution, which is easily penetrated by particles on the scale of bacteria and their flagella, but makes a substantial contribution to the macroscopic viscosity of the solution even at concentrations where 'non-Newtonian' behavior is minimal. This observation has led us to re-examine earlier measurements on the effects of viscosity on the movement of sperm flagella, which were made using methyl cellulose to increase the viscosity (Brokaw, 1966; Brokaw & Simonick, 1977)

    Color identification testing device

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    Testing device, which determines ability of a technician to identify color-coded electric wires, is superior to standard color blindness tests. It tests speed of wire selection, detects partial color blindness, allows rapid testing, and may be administered by a color blind person

    Organizational change and development : annotated and supplemental bibliography / 191

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    Includes bibliographical references (p. 48-80)

    Production/maintenance cooperative scheduling using multi-agents and fuzzy logic

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    Within companies, production is directly concerned with the manufacturing schedule, but other services like sales, maintenance, purchasing or workforce management should also have an influence on this schedule. These services often have together a hierarchical relationship, i.e. the leading function (most of the time sales or production) generates constraints defining the framework within which the other functions have to satisfy their own objectives. We show how the multi-agent paradigm, often used in scheduling for its ability to distribute decision-making, can also provide a framework for making several functions cooperate in the schedule performance. Production and maintenance have been chosen as an example: having common resources (the machines), their activities are actually often conflicting. We show how to use a fuzzy logic in order to model the temporal degrees of freedom of the two functions, and show that this approach may allow one to obtain a schedule that provides a better compromise between the satisfaction of the respective objectives of the two functions

    A Model for the Global Quantum Efficiency for a TPB-based Wavelength-Shifting System used with Photomultiplier Tubes in Liquid Argon in MicroBooNE

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    We present a model for the Global Quantum Efficiency (GQE) of the MicroBooNE optical units. An optical unit consists of a flat, circular acrylic plate, coated with tetraphenyl butadiene (TPB), positioned near the photocathode of a 20.2-cm diameter photomultiplier tube. The plate converts the ultra-violet scintillation photons from liquid argon into visible-spectrum photons to which the cryogenic phototubes are sensitive. The GQE is the convolution of the efficiency of the plates that convert the 128 nm scintillation light from liquid argon to visible light, the efficiency of the shifted light to reach the photocathode, and the efficiency of the cryogenic photomultiplier tube. We develop a GEANT4-based model of the optical unit, based on first principles, and obtain the range of probable values for the expected number of detected photoelectrons (NPEN_{\rm PE}) given the known systematic errors on the simulation parameters. We compare results from four measurements of the NPEN_{\rm PE} determined using alpha-particle sources placed at two distances from a TPB-coated plate in a liquid argon cryostat test stand. We also directly measured the radial dependence of the quantum efficiency, and find that this has the same shape as predicted by our model. Our model results in a GQE of 0.0055±0.00090.0055\pm0.0009 for the MicroBooNE optical units. While the information shown here is MicroBooNE specific, the approach to the model and the collection of simulation parameters will be widely applicable to many liquid-argon-based light collection systems.Comment: final version accepted for publication by JINS

    Physical Activity Measures in the Healthy Communities Study

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    The risk of obesity is reduced when youth engage in recommended levels of physical activity (PA). For that reason, public health organizations in the U.S. have encouraged communities to implement programs and policies designed to increase PA in youth, and many communities have taken on that challenge. However, the long-term effects of those programs and policies on obesity are largely unknown. The Healthy Communities Study is a large-scale observational study of U.S. communities that is examining the characteristics of programs and policies designed to promote healthy behaviors (e.g., increase PA and improve diet) and determining their association with obesity-related outcomes. The purpose of this paper is to describe the methods used to measure PA in children and the personal and community factors that may influence it. The study used both self-reported and objective measures of PA, and measured personal, family, and home influences on PA via three constructs: (1) PA self-schema; (2) parental support; and (3) parental rules regarding PA. Neighborhood and community factors related to PA were assessed using three measures: (1) child perceptions of the neighborhood environment; (2) availability of PA equipment; and (3) attributes of the child’s street segment via direct observation. School influences on children’s PA were assessed via three constructs: (1) school PA policies; (2) child perceptions of the school PA environment; and (3) school outdoor PA environment. These measures will enable examination of the associations between characteristics of community PA programs and policies and obesity-related outcomes in children and youth

    RNA-dependent RNA polymerase 1 in potato (Solanum tuberosum) and its relationship to other plant RNA-dependent RNA polymerases.

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    Cellular RNA-dependent RNA polymerases (RDRs) catalyze synthesis of double-stranded RNAs that can serve to initiate or amplify RNA silencing. Arabidopsis thaliana has six RDR genes; RDRs 1, 2 and 6 have roles in anti-viral RNA silencing. RDR6 is constitutively expressed but RDR1 expression is elevated following plant treatment with defensive phytohormones. RDR1 also contributes to basal virus resistance. RDR1 has been studied in several species including A. thaliana, tobacco (Nicotiana tabacum), N. benthamiana, N. attenuata and tomato (Solanum lycopersicum) but not to our knowledge in potato (S. tuberosum). StRDR1 was identified and shown to be salicylic acid-responsive. StRDR1 transcript accumulation decreased in transgenic potato plants constitutively expressing a hairpin construct and these plants were challenged with three viruses: potato virus Y, potato virus X, and tobacco mosaic virus. Suppression of StRDR1 gene expression did not increase the susceptibility of potato to these viruses. Phylogenetic analysis of RDR genes present in potato and in a range of other plant species identified a new RDR gene family, not present in potato and found only in Rosids (but apparently lost in the Rosid A. thaliana) for which we propose the name RDR7.LJRH was supported by a studentship co-funded by the James Hutton Institute (formerly Scottish Crop Research Institute) and the UK Biotechnological and Biological Sciences Research Council (BBSRC). Work in the JPC lab is funded by The Leverhulme Trust (RPG-2012-667), BBSRC (BB/D014376/1, BB/J011762/1) and the Cambridge University Newton Trust. SFB was funded by Leverhulme grant F/09-741/G to Professor Beverley Glover. KG was funded by an EMBO Short Term Fellowship. Work in the PP lab is funded by grant number NRF-2013R1A2A2A01016282 from the Korean National Research Foundation.This is the author accepted manuscript. The final version is available from Nature Publishing Group via https://doi.org/10.1038/srep2308

    Measurement of nuclide cross-sections of spallation residues in 1 A GeV 238U + proton collisions

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    The production of heavy nuclides from the spallation-evaporation reaction of 238U induced by 1 GeV protons was studied in inverse kinematics. The evaporation residues from tungsten to uranium were identified in-flight in mass and atomic number. Their production cross-sections and their momentum distributions were determined. The data are compared with empirical systematics. A comparison with previous results from the spallation of 208Pb and 197Au reveals the strong influence of fission in the spallation of 238U.Comment: 20 pages, 10 figures, background information at http://www-wnt.gsi.de/kschmidt

    Anisotropic optical response of the diamond (111)-2x1 surface

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    The optical properties of the 2×\times1 reconstruction of the diamond (111) surface are investigated. The electronic structure and optical properties of the surface are studied using a microscopic tight-binding approach. We calculate the dielectric response describing the surface region and investigate the origin of the electronic transitions involving surface and bulk states. A large anisotropy in the surface dielectric response appears as a consequence of the asymmetric reconstruction on the surface plane, which gives rise to the zigzag Pandey chains. The results are presented in terms of the reflectance anisotropy and electron energy loss spectra. While our results are in good agreement with available experimental data, additional experiments are proposed in order to unambiguously determine the surface electronic structure of this interesting surface.Comment: REVTEX manuscript with 6 postscript figures, all included in uu file. Also available at http://www.phy.ohiou.edu/~ulloa/ulloa.html Submitted to Phys. Rev.
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