Lobule-alveolar growth factor.

Publication authorized September 3, 1943.Digitized 2007 AES.Includes bibliographical references (pages 56-62)

METER, FEEL, AND PHRASING IN WEST AFRICAN BELL PATTERNS: THE EXAMPLE OF ASANTE KETE FROM GHANA

This article offers an analysis of west African bell patterns, positioning them as an entry to musical analysis of west African drumming. How can bell patterns be used as a tool by researchers to establish meter? What information do they provide about the “feel†of the music? And finally, how do these patterns interact with the underlying meter and feel, and what does this reveal about phrasing in west African music? To answer these questions, this article examines the case of the dawuro iron bell in Asante Kete drumming from Ghana. A close analysis of the Kete dawuro bell pattern reveals that the Kete pattern may be represented in an “African 12/8†or ternary-quadruple meter, emphasizes the importance of the half-time 2-feel embodying the Asante maxim of “not hurryingâ€, and demonstrates the highly motile and “goal-oriented†phrasing exemplified in Kete’s timeline patterns. To the broader west African and diasporic scholarly communities, this article presents a model for inferring meter, feel, and phrasing through close analysis of west African bell patterns

Proportional Reasoning in Middle School

The ability to reason proportionally is a foundational concept for students to master while in middle school, leading to increased understanding and deeper conceptualization of higher level mathematics and science in the later grades (Heller et al., 1989; Johnson, 2015; Lesh, Post, & Behr, 1988; Lobato & Ellis, 2010; Ellis, 2013; Carney et al., 2015). Yet mathematics education lacks research-based teaching strategies on developing proportional reasoning skills in middle school students. This study seeks to determine the influence that specific ratio relationships and models (diagrams) have on student thinking regarding a given proportional reasoning problem and its solution via cognitive interviews with 29 middle school students in Idaho. Results may inform teaching practices on proportional reasoning

Crack growth during brittle fracture in compression.

Massachusetts Institute of Technology. Dept. of Geology and Geophysics. Thesis. 1965. Ph.D.met/jhPh.D

Current & Future Applications of Artificial Intelligence in Occupational Therapy

There are three aims of this study: (1) to understand OTPs’ current use of AI within clinical settings, (2) to understand OTPs’ anticipated future integration of AI within clinical settings, and (3) to explore differences between and correlations regarding OTPs’ use of AI in practice. Research Question: How are occupational therapy practitioners using AI in their practice

Relations Between Stream Chemistry, Fish Diversity, and Land Use in the Upper Little Miami Watershed

Streams are susceptible to numerous threats to their water quality and biodiversity. In southwest Ohio a major driver of these impacts is associated with current agricultural practices and associated legacy effects. These structural and chemical impacts are known to affect biodiversity in these streams. The objective of this study was to document and examine relationships among land-use/land cover, stream chemistry, and fish diversity in the headwaters streams of the Little Miami Watershed. Three streams (Little Miami River, Massies Creek - North Fork, and Massies Creek - South Fork) were sampled in the upper headwaters as well as downstream. Air and water temperature, pH, dissolved oxygen, alkalinity, hardness and turbidity were measured in early September and late November. With the exception of temperature, the measurement of these parameters was generally consistent between sampling periods (CV \u3c 22). A total of 517 fish were collected using an electroshock backpack along 75m stretches at the sites (N = 6). In total 25 species were identified while individual sites yielded 7 - 12 species each. Fish diversity (Simpson’s Diversity, 1 - D) at our sites ranged between 0.77 and 0.86. A significant correlation (r = 0.918, p = 0.01) was found between fish diversity and the % of developed land in these watersheds. Our landscape analysis revealed that all six watersheds had 86 - 97% agricultural land use which had a negative (r = - 0.796), but not statistically significant correlation (p = 0.0581) impact on fish diversity. This work will serve as the baseline for future study of land use impacts on fish diversity, phylogeography, and water quality

Netrin-3 Peptide (C-19) is a Chemorepellent and a Growth Inhibitor in \u3cem\u3eTetrahymena thermophila\u3c/em\u3e

The netrins are a family of signaling proteins expressed throughout the animal kingdom. Netrins play important roles in developmental processes such as axonal guidance and angiogenesis. Netrin-1, for example, can act as either a chemoattractant or a chemorepellent for axonal growth cones depending upon the concentration of the protein as well as the cell type. Netrin-1 acts as a growth factor in some mammalian cell types and is also expressed by some tumor cells. Netrin-3 appears to share some signaling apparatus with netrin-1, but is less widely expressed, and its physiological roles are much less understood. Netrin-3 is also used as a biomarker for some cancers as well as traumatic kidney injury. Tetrahymena thermophila are free-living, eukaryotic, ciliated protozoas used as a model system for studying chemorepellents and chemoattractants because their swimming behavior is readily observable under a microscope. We have previously found that netrin-1 peptide acts as a chemorepellent in Tetrahymena thermophila at concentrations ranging from micromolar to nanomolar. However, netrin-1 peptide does not affect growth in Tetrahymena at these concentrations. In our current study, we have found that related peptides, netrin-3 peptide (H-19 and C-19; Santa Cruz Biotechnology), act as chemorepellents in Tetrahymena thermophila at concentrations at or below 1 μg/ml. The same concentration of netrin-3 peptide reduces growth of Tetrahymena cultures by approximately 75%. We are currently conducting further studies to determine the mechanism through which these peptides are signaling

Netrin-3 Avoidance and Mitotic Inhibition in \u3cem\u3eTetrahymena thermophila\u3c/em\u3e Involves Intracellular Calcium and Serine/Threonine Kinase Activity

Netrins are a family of signaling proteins ubiquitously expressed throughout the animal kingdom. While netrin-1 has been well characterized, other netrins, such as netrin-3, remain less well understood. In our current study, we characterize the behavior of two netrin-3 peptides, one derived from the N-terminal and one derived from the C-terminal of netrin-3. Both peptides cause avoidance behavior and mitotic inhibition in Tetrahymena thermophila at concentrations as low as 0.5 micrograms (μg) per milliliter. These effects can be reversed by addition of the calcium chelator, EGTA; the intracellular calcium chelator, BAPTA-AM, or the serine/threonine kinase inhibitor, apigenin. The broad spectrum tyrosine kinase inhibitor, genistein, has no effect on netrin-3 signaling, indicating that netrin-3 signaling in this organism uses a different pathway than the previously described netrin-1 pathway. Further studies will allow us to better describe the netrin-3 signaling pathway in this organism