628 research outputs found

    Innovations in Cover Song Detection: A Lyrics-Based Approach

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    Cover songs are alternate versions of a song by a different artist. Long being a vital part of the music industry, cover songs significantly influence music culture and are commonly heard in public venues. The rise of online music platforms has further increased their prevalence, often as background music or video soundtracks. While current automatic identification methods serve adequately for original songs, they are less effective with cover songs, primarily because cover versions often significantly deviate from the original compositions. In this paper, we propose a novel method for cover song detection that utilizes the lyrics of a song. We introduce a new dataset for cover songs and their corresponding originals. The dataset contains 5078 cover songs and 2828 original songs. In contrast to other cover song datasets, it contains the annotated lyrics for the original song and the cover song. We evaluate our method on this dataset and compare it with multiple baseline approaches. Our results show that our method outperforms the baseline approaches.Comment: 6 pages, 3 figure

    Prevalence of Disorders Recorded in Dogs Attending Primary-Care Veterinary Practices in England

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    Purebred dog health is thought to be compromised by an increasing occurence of inherited diseases but inadequate prevalence data on common disorders have hampered efforts to prioritise health reforms. Analysis of primary veterinary practice clinical data has been proposed for reliable estimation of disorder prevalence in dogs. Electronic patient record (EPR) data were collected on 148,741 dogs attending 93 clinics across central and south-eastern England. Analysis in detail of a random sample of EPRs relating to 3,884 dogs from 89 clinics identified the most frequently recorded disorders as otitis externa (prevalence 10.2%, 95% CI: 9.1-11.3), periodontal disease (9.3%, 95% CI: 8.3-10.3) and anal sac impaction (7.1%, 95% CI: 6.1-8.1). Using syndromic classification, the most prevalent body location affected was the head-and-neck (32.8%, 95% CI: 30.7-34.9), the most prevalent organ system affected was the integument (36.3%, 95% CI: 33.9-38.6) and the most prevalent pathophysiologic process diagnosed was inflammation (32.1%, 95% CI: 29.8-34.3). Among the twenty most-frequently recorded disorders, purebred dogs had a significantly higher prevalence compared with crossbreds for three: otitis externa (P = 0.001), obesity (P = 0.006) and skin mass lesion (P = 0.033), and popular breeds differed significantly from each other in their prevalence for five: periodontal disease (P = 0.002), overgrown nails (P = 0.004), degenerative joint disease (P = 0.005), obesity (P = 0.001) and lipoma (P = 0.003). These results fill a crucial data gap in disorder prevalence information and assist with disorder prioritisation. The results suggest that, for maximal impact, breeding reforms should target commonly-diagnosed complex disorders that are amenable to genetic improvement and should place special focus on at-risk breeds. Future studies evaluating disorder severity and duration will augment the usefulness of the disorder prevalence information reported herein

    Practice of ultrasound-guided arthrocentesis and joint injection, including training and implementation, in Europe: results of a survey of experts and scientific societies

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    Objectives. To document the practice and training opportunities of US-guided arthrocentesis and joint injection (UGAJ) among rheumatologists in the member countries of the European League Against Rheumatism (EULAR). Methods. An English-language questionnaire, containing questions on demographics, clinical and practical aspects of UGAJ, training options in UGAJ for rheumatologists, UGAJ education in the rheumatology training curriculum and other structured education programmes in UGAJ was sent to three different groups: (i) all national rheumatology societies of EULAR; (ii) all national societies of the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB); and (iii) 22 senior rheumatologists involved in EULAR musculoskeletal US training from 14 European countries, who were also asked to circulate the questionnaire among relevant colleagues. Results. Thirty-three (75%) of 44 countries responded to the questionnaire (61.3% of national rheumatology societies, 25% of the national US societies and 100% of expert ultrasonographers). In the majority of countries (85%) 80%) rate of rheumatologists performing conventional joint injection in most of the surveyed countries. The reported variations in practice and the lack of available structured training programmes for trainees in most countries indicates the need for standardization in areas including training guideline

    An End-to-End Performance Comparison of Seven Permissioned Blockchain Systems

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    The emergence of more and more blockchain solutions with innovative approaches to optimising performance, scalability, privacy and governance complicates performance analysis. Reasons for the difficulty of benchmarking blockchains include, for example, the high number of system parameters to configure and the effort to deploy a blockchain network. In addition, performance data, which mostly comes from system vendors, is often intransparent. We investigate and evaluate the performance of seven permissioned blockchain systems using different parameter settings in a reproducible manner. We employ an end-to-end approach, where the clients sending the transactions are fully involved in the data collection approach. Our results highlight the peculiarities and limitations of the systems under investigation. Due to the insights given, our work forms the basis for continued research to optimise the performance of blockchain systems.Comment: 14 pages, 5 figures, 20 tables, Middleware Conferenc

    Recent approaches in the development and enhancement of self-regulated learning

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    Bedingungen heutiger Schule und heutigen Studiums bringen eine erhebliche Zunahme des außerschulischen Lernens außerhalb von Präsenzphasen mit sich, was eine erhebliche Lernbelastung für Schüler und Studenten bedeutet. Für die Unterstützung und Förderung der Kompetenz zu selbstgesteuertem Lernen wurden in neuerer Zeit einige Programme entwickelt, die hier in ihren wesentlichsten Prinzipien knapp dargestellt und kritisch danach bewertet werden sollen, ob sie tatsächlich eine eigenständige Lernweggestaltung und Lernüberprüfung ermöglichen können. (DIPF/Orig.)Conditions and context of contemporary schooling and studying lead to a considerable increase in intensity and amount of learning beyond school or university. College and university students thus are confronted with operations beyond capacity. Some recent work has focussed on the development of remedial and supportive learning and schooling programs to foster and assist self-guided study. Some of these programs are sketched in their main principles. The programs are further evaluated for their factual assistance and impact on the planning, checking and control of learning by means of independent learner-guided self-regulation

    Innovations in Cover Song Detection: A Lyrics-Based Approach

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    Cover songs are alternate versions of a song by a different artist. Long being a vital part of the music industry, cover songs significantly influence music culture and are commonly heard in public venues. The rise of online music platforms has further increased their prevalence, often as background music or video soundtracks. While current automatic identification methods serve adequately for original songs, they are less effective with cover songs, primarily because cover versions often significantly deviate from the original compositions. In this paper, we propose a novel method for cover song detection that utilizes the lyrics of a song. We introduce a new dataset for cover songs and their corresponding originals. The dataset contains 5078 cover songs and 2828 original songs. In contrast to other cover song datasets, it contains the annotated lyrics for the original song and the cover song. We evaluate our method on this dataset and compare it with multiple baseline approaches. Our results show that our method outperforms the baseline approaches

    Nicotinic acetylcholine receptors modulate osteoclastogenesis

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    Background: Our aim was to investigate the role of nicotinic acetylcholine receptors (nAChRs) in in-vitro osteoclastogenesis and in in-vivo bone homeostasis. Methods: The presence of nAChR subunits as well as the in-vitro effects of nAChR agonists were investigated by ex vivo osteoclastogenesis assays, real-time polymerase chain reaction, Western blot and flow cytometry in murine bone marrow-derived macrophages differentiated in the presence of recombinant receptor activator of nuclear factor kappa B ligand (RANKL) and macrophage colony-stimulating factor (M-CSF). The bone phenotype of mice lacking various nAChR subunits was investigated by peripheral quantitative computed tomography and histomorphometric analysis. Oscillations in the intracellular calcium concentration were detected by measuring the Fura-2 fluorescence intensity. Results: We could demonstrate the presence of several nAChR subunits in bone marrow-derived macrophages stimulated with RANKL and M-CSF, and showed that they are capable of producing acetylcholine. nAChR ligands reduced the number of osteoclasts as well as the number of tartrate-resistant acidic phosphatase-positive mononuclear cells in a dose-dependent manner. In vitro RANKL-mediated osteoclastogenesis was reduced in mice lacking α7 homomeric nAChR or β2-containing heteromeric nAChRs, while bone histomorphometry revealed increased bone volume as well as impaired osteoclastogenesis in male mice lacking the α7 nAChR. nAChR ligands inhibited RANKL-induced calcium oscillation, a well-established phenomenon of osteoclastogenesis. This inhibitory effect on Ca2+ oscillation subsequently led to the inhibition of RANKL-induced NFATc1 and c-fos expression after long-term treatment with nicotine. Conclusions: We have shown that the activity of nAChRs conveys a marked effect on osteoclastogenesis in mice. Agonists of these receptors inhibited calcium oscillations in osteoclasts and blocked the RANKL-induced activation of c-fos and NFATc1. RANKL-mediated in-vitro osteoclastogenesis was reduced in α7 knockout mice, which was paralleled by increased tibial bone volume in male mice in vivo. © 2016 Mandl et al
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