2,842 research outputs found
Traumatic Myiasis Caused by an Association of <i>Sarcophaga tibialis</i> (Diptera: Sarcophagidae) and <i>Lucilia sericata</i> (Diptera: Calliphoridae) in a Domestic Cat in Italy
received: 2015-05-07 accepted: 2015-06-30 published: 2015-08-25© 2015, Korean Society for Parasitology and Tropical Medicine
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The attached file is the published version of the article.© 2015, Korean Society for Parasitology and Tropical Medicine
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The attached file is the published version of the article
A parallel pattern for iterative stencil + reduce
We advocate the Loop-of-stencil-reduce pattern as a means of simplifying the implementation of data-parallel programs on heterogeneous multi-core platforms. Loop-of-stencil-reduce is general enough to subsume map, reduce, map-reduce, stencil, stencil-reduce, and, crucially, their usage in a loop in both data-parallel and streaming applications, or a combination of both. The pattern makes it possible to deploy a single stencil computation kernel on different GPUs. We discuss the implementation of Loop-of-stencil-reduce in FastFlow, a framework for the implementation of applications based on the parallel patterns. Experiments are presented to illustrate the use of Loop-of-stencil-reduce in developing data-parallel kernels running on heterogeneous systems
La Fisica nel parco giochi fa bene anche al curriculum
Viene descritto un percorso didattico di fisica attraverso le attrazioni del parco di divertimenti di Mirabilandia (Ravenna). Viene in particolare illustrata un’esperienza di integrazione del percorso nel curriculum scolastico di fisica, condotta in una classe III di liceo scientifico, che ha avuto risultati positivi sull’apprendimento
Parâmetros biológicos dos estágios imaturos de Spodoptera eridania (Stoll, 1782) (Lepidoptera: Noctuidae), em condições controladas.
O gênero Spodoptera (Guenée, 1852) é cosmopolita e abriga grande parte das lagartas de importância agrícola. Spodoptera eridania (Stoll, 1782) é uma espécie polífaga que se alimenta de plantas de 57 famílias, incluindo muitas de importância econômica. Este estudo objetivou detalhar parâmetros biológicos de desenvolvimento dos estágios imaturos de S. eridania, em condições controladas (25 ± 1ºC, 70 ± 10% UR e fotofase de 14 horas). Foram avaliados 4.454 ovos provenientes de 16 posturas e 298 larvas neonatas, individualmente, alimentadas com dieta artificial modificada de Grenee et al. A viabilidade dos ovos, larvas, pré-pupas e pupas foi de 97,82; 93,62; 96,42; 97,03%, com duração de 4,00; 16,18; 1,58 e 9,17 dias, respectivamente. Observou-se que 93% das fêmeas e 100% dos machos passaram por seis e 7% das fêmeas passaram por sete instares larvais. A partir do quinto ínstar observou-se diferenciação no tamanho das cápsulas entre machos e fêmeas de seis instares e, entre fêmeas com as de sete instares, a diferenciação iniciou no quarto ínstar, com razão de crescimento menor que as demais, no entanto o tamanho final foi maior que nas larvas de seis instares, compensado pelo ínstar adicional. O tamanho final das cápsulas foi significativamente diferente entre fêmeas (2,64mm) e machos (2,50mm), bem como entre as fêmeas que passaram por seis (2,64mm) e sete ínstares (2,72mm). Nas larvas femininas e masculinas de seis instares a razão média de crescimento foi de 1,52 e 1,51, respectivamente; nas de sete ínstares foi de 1,44. As pupas femininas das larvas que passaram por seis instares foram significativamente maiores (377,53mg) do que os machos (329,45mg), porém, menores que as provenientes de larvas que passaram por sete ínstares (435,11mg). Tanto a metodologia de criação quanto a dieta larval foram adequadas, pois permitiram 85,87% de sobrevivência e um detalhamento muito maior das observações, especialmente, quando larvas
Activation of Serine One-Carbon Metabolism by Calcineurin A beta 1 Reduces Myocardial Hypertrophy and Improves Ventricular Function
Background In response to pressure overload, the heart develops ventricular hypertrophy that progressively decompensates and leads to heart failure. This pathological hypertrophy is mediated, among others, by the phosphatase calcineurin and is characterized by metabolic changes that impair energy production by mitochondria. Objectives The authors aimed to determine the role of the calcineurin splicing variant CnAβ1 in the context of cardiac hypertrophy and its mechanism of action. Methods Transgenic mice overexpressing CnAβ1 specifically in cardiomyocytes and mice lacking the unique C-terminal domain in CnAβ1 (CnAβ1Δi12 mice) were used. Pressure overload hypertrophy was induced by transaortic constriction. Cardiac function was measured by echocardiography. Mice were characterized using various molecular analyses. Results In contrast to other calcineurin isoforms, the authors show here that cardiac-specific overexpression of CnAβ1 in transgenic mice reduces cardiac hypertrophy and improves cardiac function. This effect is mediated by activation of serine and one-carbon metabolism, and the production of antioxidant mediators that prevent mitochondrial protein oxidation and preserve ATP production. The induction of enzymes involved in this metabolic pathway by CnAβ1 is dependent on mTOR activity. Inhibition of serine and one-carbon metabolism blocks the beneficial effects of CnAβ1. CnAβ1Δi12 mice show increased cardiac hypertrophy and declined contractility. Conclusions The metabolic reprogramming induced by CnAβ1 redefines the role of calcineurin in the heart and shows for the first time that activation of the serine and one-carbon pathway has beneficial effects on cardiac hypertrophy and function, paving the way for new therapeutic approaches
Efeito do tamanho e de múltiplos casais sobre o potencial reprodutivo de Spodoptera eridania (Stoll, 1782) (Lepidoptera: Noctuidae).
Entre os lepidópteros de importância agrícola, Spodoptera eridania (Stoll, 1782) tem despertado atenção por atingir níveis de dano econômico em culturas de importância como algodão e soja. Entretanto, existem poucos estudos detalhados de biologia, especialmente relacionados a aspectos reprodutivos. Visando determinar a capacidade máxima reprodutiva desta espécie avaliou-se o efeito do tamanho, empregando como parâmetro o peso pupal, e o número de casais por gaiola (um e três) sobre o número de cópulas, fecundidade e fertilidade. Os experimentos foram conduzidos em sala climatizada (25 ± 1ºC, 70 ± 10% UR e fotofase de 14 horas) com observações diárias. Adultos, emergidos no mesmo dia, classificados de acordo com a massa pupal, como pequenos, médios e grandes foram dispostos em gaiolas plásticas, (10 x 15cm), alimentados com dieta artificial e água estéril. Foram formadas 15 gaiolas com um casal cada, todos de tamanho médio, cinco gaiolas com 3 casais de tamanho pequeno e médio e 4 com três casais de tamanho grande. O número médio de cópulas dos casais de tamanho médio mantidos individualmente (1,13) foi significativamente menor do que o dos insetos pequenos (2,58), médios (2,47) e grandes (2,33),mantidos a três por gaiola. A fecundidade média dos casais individuais (1.398,00) também foi significativamente menor que a dos mantidos a três por gaiola, tanto de tamanho pequeno (1.709,07), médio (2.044,27) e grande (2.469,92). Entre estes últimos observou-se efeito positivo entre o tamanho da pupa e a fecundidade, com diferenças significativas entre todos os tamanhos. A fertilidade média dos casais individuais (67,45) foi muito inferior a observada para os casais pequenos (97,32%), médios (96,43%) e grandes (98,91%), mantidos a três por gaiola. Estes resultados indicam que em estudos que estimam o potencial reprodutivo devem ser utilizados pelo menos três casais por gaiola e que sejam descritos os pesos das pupas que originaram os adultos
GloPID-R report on chikungunya, o\u27nyong-nyong and Mayaro virus, part 5: Entomological aspects
The GloPID-R (Global Research Collaboration for Infectious Disease Preparedness) chikungunya (CHIKV), o\u27nyong-nyong (ONNV) and Mayaro virus (MAYV) Working Group has been established to investigate natural history, epidemiology and clinical aspects of infection by these viruses. Here, we present a report dedicated to entomological aspects of CHIKV, ONNV and MAYV. Recent global expansion of chikungunya virus has been possible because CHIKV established a transmission cycle in urban settings using anthropophilic vectors such as Aedes albopictus and Aedes aegypti. MAYV and ONNV have a more limited geographic distribution, being confined to Africa (ONNV) and central-southern America (MAYV). ONNV is probably maintained through an enzootic cycle that has not been characterized yet, with Anopheles species as main vectors and humans as amplification hosts during epidemics. MAYV is transmitted by Haemagogus species in an enzootic cycle using non-human primates as the main amplification and maintenance hosts, and humans becoming sporadically infected when venturing in or nearby forest habitats. Here, we focused on the transmission cycle and natural vectors that sustain circulation of these viruses in their respective locations. The knowledge of the natural ecology of transmission and the capacity of different vectors to transmit these viruses is crucial to understand CHIKV emergence, and to assess the risk that MAYV and ONNV will expand on wide scale using anthropophilic mosquito species not normally considered primary vectors. Finally, the experts identified knowledge gaps and provided adapted recommendations, in order to address future entomological investigations in the right direction
On an iteratively reweighted linesearch based algorithm for nonconvex composite optimization
In this paper we propose a new algorithm for solving a class of nonsmooth nonconvex problems, which is obtained by combining the iteratively reweighted scheme with a finite number of forward–backward iterations based on a linesearch procedure. The new method overcomes some limitations of linesearch forward–backward methods, since it can be applied also to minimize functions containing terms that are both nonsmooth and nonconvex. Moreover, the combined scheme can take advantage of acceleration techniques consisting in suitable selection rules for the algorithm parameters. We develop the convergence analysis of the new method within the framework of the Kurdyka– Lojasiewicz property. Finally, we present the results of a numerical experience on microscopy image super resolution, showing that the performances of our method are comparable or superior to those of other algorithms designed for this specific application
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