Donor and recipient sex in allogeneic stem cell transplantation: what really matters Donor and recipient sex in allogeneic stem cell transplantation: what really matters

Publisher's Disclaimer. E-publishing ahead of print is increasingly important for the rapid dissemination of science. Haematologica is, therefore, E-publishing PDF files of an early version of manuscripts that AUTHOR CONTRIBUTIONS H. T. K. designed the research, analyzed the data and wrote the paper. M-J.Z. analyzed the data, and reviewed the paper. A. E. W. reviewed the paper. A. S. reviewed the paper J. C. reviewed the paper W. S. reviewed the paper M. A. P. reviewed the paper P. A. designed the research, analyzed the data, and wrote the paper. M. E. designed the research, reviewed the paper. CONFLICT OF INTEREST DISCLOSURES The authors have no relevant conflicts of interest to disclose. relative increase compared with female recipients with male donors (p=0.0003). In addition, male recipients with female donors showed a 21% relative increase in the subdistribution hazard of chronic GVHD (p<0.0001) compared with female recipients with male donors. Donor sex had no effect on outcomes for female recipients. Transplantation of grafts from male and female donors was associated with inferior overall survival and progression-free survival in male recipients with differing patterns of failure. Recipient sex is an important prognostic factor independent of donor sex