Role Models\u27 Influence On Smoking Reduction

Research on social influence has indicated that role models can motivate individuals to change their behaviors and strive for success in the domains of education, occupation, and health. Positive and negative role models have been shown as effective agents of social influence through different mechanisms. Although public health advocates argue that role models can influence smoking cessation, systematic research has yet to investigate the effects of social influence on quitting smoking. The present study investigated the effects of role model influence on smoking cessation. Participants read a story about one of four role models: positive health, negative health, positive social, and negative social role model. Participants then immediately reported willingness to reduce or cease smoking behaviors. These questions were repeated two weeks later. It was found that negative role models were more effective than positive role models in motivating individuals to stop smoking. The study shows important implications for future investigations examining social influence on health-relevant behaviors such that negative role models may be most effective at motivating young adults to reduce or refrain from negative health behaviors associated with detrimental outcomes

Convo: What does conversational programming need? An exploration of machine learning interface design

Vast improvements in natural language understanding and speech recognition have paved the way for conversational interaction with computers. While conversational agents have often been used for short goal-oriented dialog, we know little about agents for developing computer programs. To explore the utility of natural language for programming, we conducted a study ($n$=45) comparing different input methods to a conversational programming system we developed. Participants completed novice and advanced tasks using voice-based, text-based, and voice-or-text-based systems. We found that users appreciated aspects of each system (e.g., voice-input efficiency, text-input precision) and that novice users were more optimistic about programming using voice-input than advanced users. Our results show that future conversational programming tools should be tailored to users' programming experience and allow users to choose their preferred input mode. To reduce cognitive load, future interfaces can incorporate visualizations and possess custom natural language understanding and speech recognition models for programming.Comment: 9 pages, 7 figures, submitted to VL/HCC 2020, for associated user study video: https://youtu.be/TC5P3OO5ex

Foreign Direct Investment in Cambodia: The case of G.E.

Cambodia, a country located on the Southern tip of Asia between Vietnam and Thailand, has been subject to incredible controversy and strife in the past century. However, in the past decade the nation has made incredible strides in their efforts to become an attractive option for foreign direct investment.General Electric Company is an American multinational company that operates through four segments—Energy, Technology Infrastructure, Capital Finance, and the Consumer and Industrial segment—in more than 100 countries. One of which is Cambodia, a dynamic country that is situated in the Lower Mekong Region. The company first launched its presence in Cambodia in July 2007 in the Healthcare, Industrial Solutions and Home and Business Solutions sectors. Today, the company has continued growing rapidly at a rate of 20% annually in the ASEAN region

Lysophosphatidylcholine Modulates Neutrophil Oxidant Production through Elevation of Cyclic AMP

Abstract Lysophosphatidylcholine (LPC) is an oxidized phospholipid present in micromolar concentrations in blood and inflamed tissues. The effects of LPC on neutrophil functions remain incompletely understood, because conflicting reports exist for its stimulatory and inhibitory roles. We report in this study that LPC inhibits superoxide generation in fMLP- and PMA-stimulated neutrophils without affecting fMLP-induced Ca2+ mobilization and cell viability. This effect was observed with LPC dissolved in ethanol, but not with LPC stock solutions prepared in water or in BSA-containing aqueous solution with sonication. Under the same experimental conditions, platelet-activating factor primed neutrophils for superoxide generation. The inhibitory effect of LPC was observed within 30 s after its application and was maximal at LPC concentrations between 0.1 and 1 μM. Inhibition of superoxide generation was accompanied by a 2.5-fold increase in the intracellular cAMP concentration. In addition, LPC reduced fMLP-stimulated phosphorylation of ERK and Akt and membrane translocation of p67phox and p47phox. The protein kinase A inhibitors H-89 and adenosine 3′5′-cyclic monophosphorothioate Rp-isomer (Rp-cAMP) partially restored superoxide production in LPC-treated neutrophils, indicating involvement of protein kinase A in LPC-mediated inhibition. Using an ex vivo mouse lung perfusion model that measures lung weight change and capillary filtration coefficient, we found that LPC prevented lung vascular injury mediated by fMLP-activated neutrophils. Taken together, these results suggest that LPC-induced elevation of intracellular cAMP is partially responsible for its inhibition of neutrophil NADPH oxidase activation. A similar mechanism of inhibition may be used for the control of neutrophil-mediated tissue injury.</jats:p

The SmithVent Experience and a Framework for Collaborative Distributed Design and Fabrication

This paper addresses the collaborative journey of the SmithVent team, a 30-person distributed group of volunteers, who designed, fabricated, and tested a simplified and cost-efficient ventilator over a three-month period, and won the CoVent19 Challenge in July 2020. The paper first presents the SmithVent experience through a co-constructed narrative that describes the team’s approaches to collaborative distributed design and fabrication. The paper next reviews frameworks from five theoretical lenses and then details the process of extracting, synthesizing, and organizing relevant factors to create a new and emergent framework reflective of the SmithVent experience. Lastly, the paper discusses educational implications of the SmithVent experience and proposed framework, emphasizing that the team’s strategies provide a model for educational and industry settings for future collaborative and distributed design and fabrication