Securing a Quantum Key Distribution Network Using Secret Sharing

We present a simple new technique to secure quantum key distribution relay networks using secret sharing. Previous techniques have relied on creating distinct physical paths in order to create the shares. We show, however, how this can be achieved on a single physical path by creating distinct logical channels. The technique utilizes a random 'drop-out' scheme to ensure that an attacker must compromise all of the relays on the channel in order to access the key

Magnetic resonance imaging (MRI) of heavy-metal transport and fate in an artificial biofilm

Unlike planktonic systems, reaction rates in biofilms are often limited by mass transport, which controls the rate of supply of contaminants into the biofilm matrix. To help understand this phenomenon, we investigated the potential of magnetic resonance imaging (MRI) to spatially quantify copper transport and fate in biofilms. For this initial study we utilized an artificial biofilm composed of a 50:50 mix of bacteria and agar. MRI successfully mapped Cu2+ uptake into the artificial biofilm by mapping T2 relaxation rates. A calibration protocol was used to convert T2 values into actual copper concentrations. Immobilization rates in the artificial biofilm were slow compared to the rapid equilibration of planktonic systems. Even after 36 h, the copper front had migrated only 3 mm into the artificial biofilm and at this distance from the copper source, concentrations were very low. This slow equilibration is a result of (1) the time it takes copper to diffuse over such distances and (2) the adsorption of copper onto cell surfaces, which further impedes copper diffusion. The success of this trial run indicates MRI could be used to quantitatively map heavy metal transport and immobilization in natural biofilms

Extending the Reach of QKD Using Relays

One of the obstacles to deployment of QKD solutions has been the distance limitation. Solutions using relays have been proposed but these rely on link-by-link key establishment. We present a new technique to extend the distance of a quantum key distribution channel using an active relay. Each relay acts as an intercept/resend device and allows the establishment of an end-to-end key. It has been argued that such relays cannot be used to extend the distance, but we show that with a suitable adaptation of the protocol the effective key distribution distance can be increased

Metagenomic sequencing unravels gene fragments with phylogenetic signatures of O2-tolerant NiFe membrane-bound hydrogenases in lacustrine sediment

Many promising hydrogen technologies utilising hydrogenase enzymes have been slowed by the fact that most hydrogenases are extremely sensitive to O2. Within the group 1 membrane-bound NiFe hydrogenase, naturally occurring tolerant enzymes do exist, and O2 tolerance has been largely attributed to changes in iron–sulphur clusters coordinated by different numbers of cysteine residues in the enzyme’s small subunit. Indeed, previous work has provided a robust phylogenetic signature of O2 tolerance [1], which when combined with new sequencing technologies makes bio prospecting in nature a far more viable endeavour. However, making sense of such a vast diversity is still challenging and could be simplified if known species with O2-tolerant enzymes were annotated with information on metabolism and natural environments. Here, we utilised a bioinformatics approach to compare O2-tolerant and sensitive membrane-bound NiFe hydrogenases from 177 bacterial species with fully sequenced genomes for differences in their taxonomy, O2 requirements, and natural environment. Following this, we interrogated a metagenome from lacustrine surface sediment for novel hydrogenases via high-throughput shotgun DNA sequencing using the Illumina™ MiSeq platform. We found 44 new NiFe group 1 membrane-bound hydrogenase sequence fragments, five of which segregated with the tolerant group on the phylogenetic tree of the enzyme’s small subunit, and four with the large subunit, indicating de novo O2-tolerant protein sequences that could help engineer more efficient hydrogenases

Spherical Code Key Distribution Protocols for Qubits

Recently spherical codes were introduced as potentially more capable ensembles for quantum key distribution. Here we develop specific key creation protocols for the two qubit-based spherical codes, the trine and tetrahedron, and analyze them in the context of a suitably-tailored intercept/resend attack, both in standard form, and a ``gentler'' version whose back-action on the quantum state is weaker. When compared to the standard unbiased basis protocols, BB84 and six-state, two distinct advantages are found. First, they offer improved tolerance of eavesdropping, the trine besting its counterpart BB84 and the tetrahedron the six-state protocol. Second, the key error rate may be computed from the sift rate of the protocol itself, removing the need to sacrifice key bits for this purpose. This simplifies the protocol and improves the overall key rate.Comment: 4 pages revtex, 2 figures; clarified security analysis. Final version for publicatio

Dynamics of impurity, local and non-local information for two non identical qubits

From the separability point of view the problem of two atoms interact with a single cavity mode is investigated. The density matrix is calculated and used to discuss the entanglement and to examine the dynamics of the local and non-local information. Our examination concentrated on the variation in the mean photon number and the ratio of the coupling parameters. Furthermore, we have also assumed that the atomic system is initially in the ground states as well as in the intermediate states. It has been shown that the local information is transferred to non-local information when the impurity of one qubit or both is maximum

Tool construction for the British Airways SEE with the O<inf>2</inf> ODBMS

Software engineering environments (SEE) support the construction and maintenance of large-scale software systems. They integrate tools for the production and maintenance of documents such as requirements definitions, architecture definitions or user manuals. Very few SEE tools meet all the developers' requirements. Some requirements that are important in practice have not been appropriately addressed. These are inter-document consistency handling, version and configuration management and cooperative work. We claim that the reason for current tools not meeting these requirements is the fact that the required database support for maintaining documents is only now becoming available. The British Airways SEE meets these new requirements. Its tools were constructed using the O2 object database management system, which has been extended to become a database management system for software engineering. We discuss the experiences we made during tool construction for this SEE

Low pH enhances the action of maximin H5 against Staphylococcus aureus and helps mediate lysylated phosphatidylglycerol induced resistance

Maximin H5 (MH5) is an amphibian antimicrobial peptide specifically targeting Staphylococcus aureus. At pH 6, the peptide showed an increased ability to penetrate (∆П = 6.2 mN m-1) and lyse (lysis = 48 %) S. aureus membrane mimics, which incorporated physiological levels of lysylated phosphatidylglycerol (Lys-PG, 60 %) as compared to pH 7 (∆П = 5.6 mN m-1 and lysis = 40 % at pH 7) where levels of Lys-PG are lower (40 %). The peptide therefore appears to have optimal function at pH levels known to be optimal for the organism’s growth. MH5 killed S. aureus (minimum inhibitory concentration = 90 µM) via membranolytic mechanisms that involved the stabilization of α-helical structure (circa 45-50 %) and which showed similarities to the ‘Carpet’ mechanism based on its ability to increase the rigidity (Cs-1 = 109.94 mN m-1) and thermodynamic stability (∆Gmix = -3.0) of physiologically relevant S. aureus membrane mimics at pH 6. Based on theoretical analysis this mechanism may involve the use of a tilted peptide structure and efficacy was noted to vary inversely with the Lys-PG content of S. aureus membrane mimics for each pH studied (R2 circa 0.97), which led to the suggestion that under biologically relevant conditions, low pH helps mediate Lys-PG induced resistance in S. aureus to MH5 antibacterial action. The peptide showed a lack of haemolytic activity (< 2 % haemolysis) and merits further investigation as a potential template for development as an anti-staphylococcal agent in medically and biotechnically relevant areas