617 research outputs found
No means no - but when does yes mean yes? : the legal validity of a voluntarily intoxicated consent to sex
Le Peneroplidi dei sedimenti recenti del Mediterraneo e del Golfo Persico
Questa nota riguarda lo studio di popolazioni differenti di Peneroplidi
e le loro variazioni morfologiche individuali. I campioni sono stati prelevati,
sempre a debole profondità, vicino alla costa. In Sardegna lungo la
spiaggia di Golfo Aranci, nel Golfo Persico lungo la spiaggia di Aziziyah
(a 1O Km circa a Sud di Alkhobar) e nella laguna interna Rawhat as Sayh
Abundance, diversity and distribution of macrophyte communities in neighboring lakes of different trophic states and morphology in north-central Greece
The role of aquatic vegetation in wetland ecosystems is closely related with their abundance, diversity and distribution, which in turn represents synergy of various environmental factors. The floristic composition of the aquatic vegetation in two neighboring lakes (Vegoritida and Petron) in north-central Greece was investigated by means of 160 relevés, which were recorded using the Braun-Blanquet method. The analysis of relevés based on TWINSPAN clustering showed the existence of 10 plant communities from the Lemnetea, Potametea, Phragmito-Magnocaricetea and Juncetea maritimi classes. The most important environmental factors for the vegetation differentiation in the study area, according to the ordination diagram, are light intensity and water depth of the habitats. The plant species diversity was quantified with species richness, Shannon Diversity and evenness indices at a scale of each relevé, with a sampling size of 20 m2. There was a clear differentiation between the relevés at the more eutrophic Petron Lake and those at Vegoritida Lake. The mean plot diversity was also calculated for each plant community, to enable comparison of the diversity indices among the communities at the plot level
MIDDLE EOCENE TO EARLY MIOCENE FORAMINIFERAL BIOSTRATIGRAPHY IN THE EPILIGURIAN SUCCESSION (NORTHERN APENNINES, ITALY)
A quantitative biostratigraphical study was performed on the foraminiferal assemblages from 15 stratigraphic sections of the Epiligurian Succession (Middle Eocene-Early Miocene, Northern Apennines, Italy). This study enabled us to identify the presence of some of the standard bioevents and to note that other bioevents are absent or show a different chronostratigraphic range. Other additional bioevents, identified throughout the area, have therefore been utilised to improve the biostratigraphical resolution of the Epiligurian sediments. These bioevents include the massive extinction of the muricate species at the Bartonian/Priabonian boundary; the increasing abundance of Paragloborotalia opima opima near Subzone P21a/P21b and the Rupelian/Chattian boundaries; and the FO of Globoquadrina dehiscens at the Subzone N4a/N4b boundary. 
Early detection of gastric cancer using global, genome-wide and IRF4, ELMO1, CLIP4 and MSC DNA methylation in endoscopic biopsies
Clinically useful molecular tools to triage gastric cancer patients are not currently available. We aimed to develop a molecular tool to predict gastric cancer risk in endoscopy-driven biopsies obtained from high-risk gastric cancer clinics in low resource settings.We discovered and validated a DNA methylation biomarker panel in endoscopic samples obtained from 362 patients seen between 2004 and 2009 in three high-risk gastric cancer clinics in Lima, Perú, and validated it in 306 samples from the Cancer Genome Atlas project ( TCGA ). Global, epigenome wide and gene-specific DNA methylation analyses were used in a Phase I Biomarker Development Trial to identify a continuous biomarker panel that combines a Global DNA Methylation Index (GDMI) and promoter DNA methylation levels of IRF4, ELMO1, CLIP4 and MSC.We observed an inverse association between the GDMI and histological progression to gastric cancer, when comparing gastritis patients without metaplasia (mean = 5.74, 95% CI, 4.97-6.50), gastritis patients with metaplasia (mean = 4.81, 95% CI, 3.77-5.84), and gastric cancer cases (mean = 3.38, 95% CI, 2.82-3.94), respectively (p \u3c 0.0001). Promoter methylation of IRF4 (p \u3c 0.0001), ELMO1 (p \u3c 0.0001), CLIP4 (p \u3c 0.0001), and MSC (p \u3c 0.0001), is also associated with increasing severity from gastritis with no metaplasia to gastritis with metaplasia and gastric cancer.Our findings suggest that IRF4, ELMO1, CLIP4 and MSC promoter methylation coupled with a GDMI\u3e4 are useful molecular tools for gastric cancer risk stratification in endoscopic biopsies
Stepi podobna traviška vegetacija na hribih okoli jezer Vegoritida in Petron v severno centralni Grčiji
The present paper describes the floristic composition and synecology of steppe-like dry grasslands occurring in a Natura 2000 site in North-Central Greece around the two karstic lakes of Vegoritida and Petron. In total, 245 relevés of vascular plant species composition and abundance were sampled and subjected to cluster analysis and ordination analysis. Passive explanatory variables, including environmental parameters as well as indicator values, were used to support the ecological interpretation. Four plant communities were distinguished in the area, namely Artemisia campestris-Dasypyrum villosum, Chrysopogon gryllus-Bothriochloa ischaemum, Satureja montana-Artemisia alba and Stipa capillata-Koeleria macrantha. All communities were classified within the Festuco-Brometea class and the Astragalo-Potentilletalia order. Soil properties (soil reaction, moisture and nutrient content) and meso-climate factors (temperature variation along topographic gradients) were identified as the main factors determining the floristic differentiation among the four communities. The dry grasslands harbor a number of species associated with steppic habitats. We discuss the relict character of the steppe-like vegetation.V članku opisujemo floristično sestavo in sinekologijo stepi podobnih suhih travišč, ki se pojavljajo v Natura 2000 območju v severni centralni Grčiji okoli dveh kraških jezer Vegoritida in Petron. Vzorčili smo 245 vegetacijskih popisov in jih analizirali s klastrsko in ordinacijsko analizo. Rastišče smo interpretirali s pasivnimi pojasnjevalnimi spremenljivkami, kamor smo vključili okoljske spremenljivke in indikatorske vrednosti. Na raziskovanem območju smo ločili štiri rastlinske združbe: Artemisia campestris-Dasypyrum villosum, Chrysopogon gryllus-Bothriochloa ischaemum, Satureja montana-Artemisia alba in Stipa capillata-Koeleria macrantha. Vse združbe smo uvrstili v razred Festuco-Brometea in red Astragalo-Potentilletalia. Lastnosti tal (reakcija tal) in mezo klimatski dejavniki (spreminjanje temperature vzdolž topografskih gradientov) so glavni dejavniki, ki vplivajo na floristične razlike med štirimi rastlinskimi združbami. V suhih traviščih najdemo številne vrste stepskih habitatov. V članku razpravljamo o reliktnem značaju stepi podobne vegetacije
Research into tutoring: exploring agency and intersubjectivity
This thesis explores the notions of agency and intersubjectivity, using knowledge communication in research into high school tutoring as an example. Both agency and intersubjectivity are central to communication, but thus far, empirically applicable theoretical and methodological tools to investigate these notions have been lacking. This thesis attempts to fill this gap.
Using multimodal (inter)action analysis as the underlying theoretical and methodological framework and recorded tutoring research sessions as the data, this thesis develops three theoretical/methodological tools:
1. Primary agency; 2. Handing primary agency from one social actor to another; and 3. Tiers of intersubjectivity.
The analytical part of the thesis comprises four analysis chapters and one discussion chapter. The first three analysis chapters establish the new theoretical/methodological tools; the fourth analysis chapter showcases what these tools have to offer; and the discussion chapter entails some further analysis in order to engage with and critically examine current literature.
First, the thesis demonstrates that one social actor often expresses primary agency over a co-produced higher-level action. Primary agency is recognisable through an identification of agency over the most relevant meditational means, and thus becomes an applicable methodological tool. The thesis proposes that successful knowledge communication may rely on a social actor producing an action with primary agency.
Second, the thesis develops the notion of co-production by showing that social actors hand primary agency to one another during dyadic and triadic interaction. By linking semantic/pragmatic means that indicate shifts in attention/awareness to the notion of handing of primary agency, handing (or taking on) primary agency becomes a methodological tool.
Third, the thesis illustrates how students establish intersubjectivity with tutors. Here, it is theorised that social actors in interaction first establish a stable and adjustable intersubjectivity, before going on to establish more fleeting intersubjectivity. By taking the notion of modal configurations as the starting point, these three levels of intersubjectivity build an empirically applicable methodological tool, i.e.: tiers of intersubjectivity.
Fourth, the theoretical and methodological tools are then utilised to analyse how novel objects are taken up in tutoring, and how mediational means are used for knowledge communication. Here, the thesis demonstrates that successful knowledge communication requires coherence between the social actor, the mediational means and the knowledge to be communicated.
The thesis contributes to the theoretical/methodological framework of multimodal (inter)action analysis as well as to the field of knowledge communication. Empirically, the thesis contributes to our understanding of dyadic and triadic interaction and to tutoring as knowledge communication
Distributed Information Systems and Data Mining in Self-Organizing Networks
The diffusion of sensors and devices to generate and collect data is capillary. The infrastructure that envelops the smart city has to react to the contingent situations and to changes in the operating environment. At the same time, the complexity of a distributed system, consisting of huge amounts of components fixed and mobile, can generate unsustainable costs and latencies to ensure robustness, scalability, and reliability, with type architectures middleware. The distributed system must be able to self-organize and self-restore adapting its operating strategies to optimize the use of resources and overall efficiency. Peer-to-peer systems (P2P) can offer solutions to face the requirements of managing, indexing, searching and analyzing data in scalable and self-organizing fashions, such as in cloud services and big data applications, just to mention two of the most strategic technologies for the next years.
In this thesis we present G-Grid, a multi-dimensional distributed data indexing able to efficiently execute arbitrary multi-attribute exact and range queries in decentralized P2P environments. G-Grid is a foundational structure and can be effectively used in a wide range of application environments, including grid computing, cloud and big data domains.
Nevertheless we proposed some improvements on the basic structure introducing a bit of randomness by using Small World networks, whereas are structures derived from social networks and show an almost uniform traffic distribution. This produced huge advantages in efficiency, cutting maintenance costs, without losing efficacy. Experiments show how this new hybrid structure obtains the best performance in traffic distribution and it a good settlement for the overall performance on the requirements desired in the modern data systems
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