Primary cutaneous coccidioidomycosis and subsequent drug eruption to itraconazole in a dog

Three weeks after traveling to Arizona, a 13-month-old, female Labrador retriever developed draining tracts in the right hind limb. Primary cutaneous coccidioidomycosis was diagnosed. Initial treatment with itraconazole resulted in exacerbation of clinical signs. Histopathology was suggestive of a cutaneous drug eruption. Discontinuation of the itraconazole caused resolution of the drug eruption. Successful treatment of the fungal infection was achieved using ketoconazole.</jats:p

The Effects of Statutory Rape Laws on Nonmarital Teenage Childbearing

Many policy makers view the enforcement of statutory rape laws as a way to reduce teenage childbirths. This article considers whether unmarried teenage girls covered by a state statutory rape law are less likely to give birth than girls who are not covered by a statutory rape law. The presence of statutory rape laws is negatively correlated with nonmarital birthrates for white females but is not a significant predictor for black or Hispanic females. In contrast, the enforcement of statutory rape laws has a deterrent effect on teen childbearing for blacks and Hispanics but not for whites. (JEL J13,K14)AMS. No Keywords

Evaluation of day-to-day variability of serial blood glucose concentration curves in diabetic dogs

Objective - To evaluate day-to-day variability of serial blood glucose concentration curves in dogs with diabetes mellitus. Design - Prospective clinical study. Animals - 10 dogs with diabetes mellitus. Procedure - Paired 12-hour serial blood glucose concentration curves performed during 2 consecutive days were obtained on 3 occasions from each dog. Dogs received the same dose of insulin and meal every 12 hours on both days. For each pair of curves, comparison was made between the results of days 1 and 2. Results - Mean absolute difference (without regard to sign) between days 1 and 2 for each parameter was significantly > 0, disproving the hypothesis that there is minimal day-to-day variability of serial blood glucose concentration curves when insulin dose and meals are kept constant. Coefficient of variation of the absolute difference between days 1 and 2 for each parameter ranged from 68 to 103%. Evaluation of the paired curves led to an opposite recommendation for adjustment of the insulin dose on day 2, compared with day 1, on 27% of occasions. Disparity between dosage recommendations was more pronounced when glucose concentration nadir was < 180 mg/dL (10 mmol/L) on 1 or both days. In this subset of 20 paired curves, an opposite recommendation for dosage adjustment was made on 40% of occasions. Conclusions and Clinical Relevance - There is large day-to-day variation in parameters of serial blood glucose concentration curves in diabetic dogs. Day-to-day variability of serial blood glucose concentration curves has important clinical implications, particularly in dogs with good glycemic control

Capping Kids: The Family Cap and Nonmarital Childbearing

Welfare reform, Nonmarital childbearing, Family cap,