683 research outputs found

    L’idée de justice sociale : le pluralisme en question

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    Il convient de résister à la critique positiviste et d’affirmer la nécessité de normes de justice universalisables. Ces dernières doivent s’ouvrir aux exigences du pluralisme tout en restant fidèles aux principes fondateurs des démocraties libérales.Note publiée sur le site du Cevipof "Elections 2012" In "Le recueil des notes du Cevipof - Les enjeux

    Survival rates associated with in vitro low-temperature storage of kutum (Rutilus kutum) eggs

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    To study the effects of post-stripping oocyte ageing at low temperatures on the viability of kutum (Rutilus kutum) oocytes, unfertilised eggs of five females were stored in ovarian fluid at temperatures of 4 and 7 degrees centigrade for 24 hours post stripping (HPS). The stored ova of five female kutum were separately fertilised at 0 (i.e., control eggs fertilised prior to storage), 4, 8, 12, 16, 20, and 24 HPS. The eyeing and hatching rates were recorded as indices of the egg quality. The results indicated that the maximum eyeing and hatching rates of the eggs (92% and 74%, respectively) were observed at 0 HPS, whereas the storage of the eggs at 4 °C for 24 HPS decreased the eyeing and hatching rates to 36% and 28%, respectively. The use of the higher storage temperature resulted in a more rapid decrease in the egg viability: eyeing and hatching rates of 9% and 2%, respectively, were obtained after storage at 7 °C for 24 HPS. The present study demonstrated that stripped kutum eggs that are stored in ovarian fluid at 4 and 7 degrees centigrade should be fertilised within 12 and 8 HPS, respectively, to obtain viability rates higher than 50%

    Synthesis and cellular uptake of superparamagnetic dextran-nanoparticles with porphyrinic motifs grafted by esterification

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    International audienceThis paper describes new superparamagnetic nanoparticles bearing dextran-grafted porphyrins with effective cellular uptake properties. They average 110 nm in diameter and are composed of a 5 nm iron oxide core coated with protoporphyrin grafted dextrans. These particles show good magnetic properties, are avidly incorporated into cultured cancer cell lines, and thus present a great potential for cellular imaging and photodynamic therapy applications

    Thank you for Not Grading

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    This paper presents opinions as to why letter grades should be discontinued as an assessment method for work completed in Student Development Administration graduate programs. It is the author’s opinion that letter grades are an inferior evaluative method when compared to more in-depth written evaluations from professors accompanied by personal reflections from graduate students. The paper is comprised of observations made as a graduate student and is augmented by observations of professionals practicing as student development administrators.

    THE FECUNDITY, TIME OF EGG DEVELOPMENT AND JUVENILE PRODUCTION IN SPINY-CHEEK CRAYFISH (ORCONECTES LIMOSUS) UNDER CONTROLLED CONDITIONS

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    We comprehensively describe the fecundity and time of embryonic development of the spiny-cheek crayfish (Orconectes limosus). Linear relationships between female size and ovarian fecundity, pleopodal fecundity, and production of juveniles at the 3rd stage, were confirmed. The ovarian fecundity was evaluated for the smallest as well as largest females in the sampled population (43-93 mm of body length); the number of oocytes (eggs) ranged widely, between 46 and 505. No significant difference was found between the ovarian and pleopodal fecundity observed just after egg laying. The value of the female gonadosomatic index just before laying was 4.2 ± 1.8% (0.8-7.7%). The mean diameter of eggs on female pleopods was 1.8 ± 0.2 mm (1.45-2.15 mm). A statistically significant difference was found between the numbers of eggs carried on individual pairs of pleopods. Mean time from laying to hatching was 46 ± 3.8 days (37-56 days), i.e. 647 ± 39.9 CTU (Celsius Temperature Units = degrees Celsius × days). Mean production of juveniles at the 3rd stage was found to be 135.7 ± 67.24 (15-243) juveniles. The early sexual maturation and also high number of juveniles at the 3rd stage per female gives this species a good predisposition for quick establishment in new localities

    Acute Hepatitis B and Acute HIV Coinfection in an Adult Patient: A Rare Case Report

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    Acute HIV and acute hepatitis B coinfection is extremely rare. A 23-year-old homosexual man was admitted to our hospital with 5-day history of fever, malaise, and back pain with initial laboratory values showing severe transaminitis. The clinical picture was initially suggestive of acute viral hepatitis, which on further testing revealed acute hepatitis B and acute HIV coinfection. Although the patient was asymptomatic, a decision was made to start antiretroviral therapy. At 2-month followup, liver function tests were normal with undetectable viral loads. The early treatment of acute HIV/HBV coinfections likely contributed to eventual seroconversion with immunity to HBV in a severely immunocompromised host. To the best of our knowledge, this is the first case report of acute Hepatitis B and acute HIV coinfection and its management. In conclusion, early treatment of acute hepatitis B in immunocompromised patients may be beneficial

    Astigmatism and cyclovergence

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    Vpráci je popsáno vyšetření astigmatismu a jeho vlivna spokojenost zákazníků storickou korekcí. Prácepopisuje astigmatismusa jeho dělení. Dáleshrne objektivní i subjektivní metody jeho vyšetřování. Vdalšíčásti zkoumá mechanismy pohybů očního bulbu apotíže storickou korekcí způsobené cyklotorzními kompenzačními pohyby oka. Tyto pohybynapomáhají jednoduchému binokulárnímuvidění při binokulární fixaci. V praktickéčásti jsou určeny rozdílymezi klasickým, monokulárním vyšetřením a vyšetřením astigmatismu za binokulárních podmínek. Výsledky analýzy jsoushrnuty a rozebrány zhlediska významu vlivu cyklotorzních pohybů na správnost výsledné korekce astigmatismuThe work describes the examination of astigmatism and its impact on customer satisfaction with toric correction. It describes the astigmatism and its divisions. Furthermore, recaps objective and subjective methods of its investigation. The next section examines the mechanism of the eyeballmovements and problems with toric correction caused by cyclotorsionalcompensatory eye movements. These movemementshelpssimple binocular vision during binocular fixation. In the practical section are examinated differences between classical, monocular examination and testing of astigmatism under binocular conditions. Results of the analysis are summarized and analyzed in light of the importanc e of the influence of cyclotorsionalmovements on the accuracy of the resulting astigmatism correction

    Karl Heinrich Heydenreich and His Prospect of "Kantian" Aesthetics before Critique of Judgement

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    Karl Heinrich Heydenreich a his Prospect of "Kantian" Aesthetics before the Critique of Judgment Dissertation Mgr. Antonín Policar Abstract The aim of my thesis is to provide an insight into the aesthetic thought of the German Enlightenment philosopher and professor at the Leipzig University Karl Heinrich Heydenreich (1764-1801). I will analyze his various attempts during the 1780s to adapt the German tradition of philosophical aesthetics to the newly emerging transcendental paradigm introduced to philosophy by Immanuel Kant. The main focus will be on the question if Heydenreich's aesthetic writings prior to 1790 can be justifiably considered (as it has been repeatedly, but without convincing arguments pointed out by historians of aesthetics) a predecessor, or even a parallel to Kant's Critique of Judgement.Karl Heinrich Heydenreich a jeho vize "kantovské" estetiky před Kritikou soudnosti Disertační práce Mgr. Antonín Policar Abstrakt Cílem mé disertace je zprostředkovat vhled do estetiky německého pozdně osvícenského filosofa Karla Heinricha Heydenreicha (1764-1801) a ukázat, jak se v jeho pojetí tato ve středoevropském německojazyčném prostoru tradičně ukotvená filosofická disciplína na konci 80. let 18. století vyrovnávala s novými výzvami souvisejícími s nástupem transcendentální filosofie Immanuela Kanta. Konkrétně budu hledat odpověď na otázku, nakolik a zda vůbec je možné Heydenreichovo estetické dílo před rokem 1790 považovat (tak, jak na to opakovaně, avšak bez pádných argumentů, poukazovala dosavadní literatura) za předchůdce, ba dokonce za srovnatelnou alternativu Kantovy Kritiky soudnosti.Katedra estetikyDepartment of AesteticsFaculty of ArtsFilozofická fakult

    Cymantrene, Cyrhetrene and Ferrocene Nucleobase Conjugates: Synthesis, Structure, Computational Study, Electrochemistry and Antitrypanosomal Activity

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    A series of cymantrene- and cyrhetrene-nucleobase derivatives together with the ferrocene-adenine conjugates have been prepared and characterized. The key step in synthesis of all compounds involved an N1-regioselective Michael addition of the respective nucleobase nucleophile to an in situ generated organometallic acryloyl electrophile reagent. The mechanism of this reaction was examined by DFT calculations. A single crystal X-ray diffraction study of cymantrene-adenine (5) were carried out and revealed that the plane of the adenine and the cyclopentadienyl group are almost perpendicular to each other. The cyclic voltammetry measurements on the cymantrenyl-nucleobases showed irreversible behavior for all compounds which can be explain by a ligand exchange of carbonyls with the donor functionality of the nucleobases. Cymantrene and cyrhetrene ketone nucleobases displayed significant in vitro activity against Trypanosoma brucei a causative parasite of sleeping sickness. They showed no cytotoxicity against human HL-60 cancer cells

    COMPARISON OF TRAP AND BAITED STICK CATCH EFFICIENCY FOR NOBLE CRAYFISH (ASTACUS ASTACUS L.) IN THE COURSE OF THE GROWING SEASON

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    Noble crayfish (Astacus astacus) were caught using traps and baited sticks in Svğtlohorská reservoir in the Czech Republic, and the catch efficiency and size and sex composition in catches were compared during the growing season (May-September). One trapping period per month (1.5 hour from 6-7: 30 pm) was applied. Trap catches were significantly higher in September compared to the other months, and baited stick catches were significantly higher in May, June and September. Baited sticks were significantly more effective than traps in all months except in July. Males dominated in all catches, except in September trap catches. Females were totally absent in traps in June, July and August. Baited sticks caught females more successfully than traps, especially females with eggs. Traps did not catch any females with eggs. Males and females caught by baited sticks were of larger size range (range of body length 60-125 mm) than those caught by traps (range of body length 75-120 mm) however, there were no significant differences in mean size. Due to high catch efficiency, baited sticks may be considered as an appropriate catching gear in crayfish monitoring projects, especially when a short-time catching effort is required
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