Etching of aluminum for bonding Patent

Etching aluminum alloys with aqueous solution containing sulfuric acid, hydrofluoric acid, and an alkali metal dischromate for adhesive bondin

High-concentration Er:YAG single-crystal fibers grown by laser-heated pedestal growth technique

High-concentration Er:YAG single-crystal fibers have been grown using the laser-heated pedestal growth technique. Instability in the melt and concomitant opacity of fibers were observed at source concentrations higher than 15 mol.%. Spectroscopic examination shows that broadening of the linewidth of the I<sub>13/2</sub>4→I<sub>15/2</sub>4 transition is strongly dependent on Er<sup>3+</sup> concentration

Stratospheric aerosol modification by supersonic transport operations with climate implications

The potential effects on stratospheric aerosois of supersonic transport emissions of sulfur dioxide gas and submicron size soot granules are estimated. An interactive particle-gas model of the stratospheric aerosol is used to compute particle changes due to exhaust emissions, and an accurate radiation transport model is used to compute the attendant surface temperature changes. It is shown that a fleet of several hundred supersonic aircraft, operating daily at 20 km, could produce about a 20% increase in the concentration of large particles in the stratosphere. Aerosol increases of this magnitude would reduce the global surface temperature by less than 0.01 K

VLBI Polarimetry of 177 Sources from the Caltech-Jodrell Bank Flat-spectrum Survey

We present VLBA observations and a statistical analysis of 5 GHz VLBI polarimetry data from 177 sources in the Caltech-Jodrell Bank flat-spectrum (CJF) survey. The CJF survey, a complete, flux-density-limited sample of 293 extragalactic radio sources, gives us the unique opportunity to compare a broad range of source properties for quasars, galaxies and BL Lacertae objects. We focus primarily on jet properties, specifically the correlation between the jet axis angle and the polarization angle in the core and jet. A strong correlation is found for the electric vector polarization angle in the cores of quasars to be perpendicular to the jet axis. Contrary to previous claims, no correlation is found between the jet polarization angle and the jet axis in either quasars or BL Lac objects. With this large, homogeneous sample we are also able to investigate cosmological issues and AGN evolution.Comment: Accepted to the Astrophysical Journal: 37 pages, 14 figure

Adsorption and two-body recombination of atomic hydrogen on 3^3He-4^4He mixture films

We present the first systematic measurement of the binding energy $E_a$ of hydrogen atoms to the surface of saturated $^3$He-$^4$He mixture films. $E_a$ is found to decrease almost linearly from 1.14(1) K down to 0.39(1) K, when the population of the ground surface state of $^3$He grows from zero to $6\times10^{14}$ cm$^{-2}$, yielding the value $1.2(1)\times 10^{-15}$ K cm$^2$ for the mean-field parameter of H-$^3$He interaction in 2D. The experiments were carried out with overall $^3$He concentrations ranging from 0.1 ppm to 5 % as well as with commercial and isotopically purified $^4$He at temperatures 70...400 mK. Measuring by ESR the rate constants $K_{aa}$ and $K_{ab}$ for second-order recombination of hydrogen atoms in hyperfine states $a$ and $b$ we find the ratio $K_{ab}/K_{aa}$ to be independent of the $^3$He content and to grow with temperature.Comment: 4 pages, 4 figures, all zipped in a sigle file. Submitted to Phys. Rev. Let

The EU and Asia within an evolving global order: what is Europe? Where is Asia?

The papers in this special edition are a very small selection from those presented at the EU-NESCA (Network of European Studies Centres in Asia) conference on "the EU and East Asia within an Evolving Global Order: Ideas, Actors and Processes" in November 2008 in Brussels. The conference was the culmination of three years of research activity involving workshops and conferences bringing together scholars from both regions primarily to discuss relations between Europe and Asia, perceptions of Europe in Asia, and the relationship between the European regional project and emerging regional forms in Asia. But although this was the last of the three major conferences organised by the consortium, it in many ways represented a starting point rather than the end; an opportunity to reflect on the conclusions of the first phase of collaboration and point towards new and continuing research agendas for the future

Carbon Free Boston: Technical Summary

Part of a series of reports that includes: Carbon Free Boston: Summary Report; Carbon Free Boston: Social Equity Report; Carbon Free Boston: Buildings Technical Report; Carbon Free Boston: Transportation Technical Report; Carbon Free Boston: Waste Technical Report; Carbon Free Boston: Energy Technical Report; Carbon Free Boston: Offsets Technical Report; Available at http://sites.bu.edu/cfb/OVERVIEW: This technical summary is intended to argument the rest of the Carbon Free Boston technical reports that seek to achieve this goal of deep mitigation. This document provides below: a rationale for carbon neutrality, a high level description of Carbon Free Boston’s analytical approach; a summary of crosssector strategies; a high level analysis of air quality impacts; and, a brief analysis of off-road and street light emissions.Published versio

Antibody-Based Ticagrelor Reversal Agent in Healthy Volunteers.

BACKGROUND: Ticagrelor is an oral P2Y12 inhibitor that is used with aspirin to reduce the risk of ischemic events among patients with acute coronary syndromes or previous myocardial infarction. Spontaneous major bleeding and bleeding associated with urgent invasive procedures are concerns with ticagrelor, as with other antiplatelet drugs. The antiplatelet effects of ticagrelor cannot be reversed with platelet transfusion. A rapid-acting reversal agent would be useful. METHODS: In this randomized, double-blind, placebo-controlled, phase 1 trial, we evaluated intravenous PB2452, a monoclonal antibody fragment that binds ticagrelor with high affinity, as a ticagrelor reversal agent. We assessed platelet function in healthy volunteers before and after 48 hours of ticagrelor pretreatment and again after the administration of PB2452 or placebo. Platelet function was assessed with the use of light transmission aggregometry, a point-of-care P2Y12 platelet-reactivity test, and a vasodilator-stimulated phosphoprotein assay. RESULTS: Of the 64 volunteers who underwent randomization, 48 were assigned to receive PB2452 and 16 to receive placebo. After 48 hours of ticagrelor pretreatment, platelet aggregation was suppressed by approximately 80%. PB2452 administered as an initial intravenous bolus followed by a prolonged infusion (8, 12, or 16 hours) was associated with a significantly greater increase in platelet function than placebo, as measured by multiple assays. Ticagrelor reversal occurred within 5 minutes after the initiation of PB2452 and was sustained for more than 20 hours (P\u3c0.001 after Bonferroni adjustment across all time points for all assays). There was no evidence of a rebound in platelet activity after drug cessation. Adverse events related to the trial drug were limited mainly to issues involving the infusion site. CONCLUSIONS: In healthy volunteers, the administration of PB2452, a specific reversal agent for ticagrelor, provided immediate and sustained reversal of the antiplatelet effects of ticagrelor, as measured by multiple assays. (Funded by PhaseBio Pharmaceuticals; ClinicalTrials.gov number, NCT03492385.)

Three-dimensional Calculations of High and Low-mass Planets Embedded in Protoplanetary Discs

We analyse the non-linear, three-dimensional response of a gaseous, viscous protoplanetary disc to the presence of a planet of mass ranging from one Earth mass (1 M$_e$) to one Jupiter mass (1 M$_J$) by using the ZEUS hydrodynamics code. We determine the gas flow pattern, and the accretion and migration rates of the planet. The planet is assumed to be in a fixed circular orbit about the central star. It is also assumed to be able to accrete gas without expansion on the scale of its Roche radius. Only planets with masses M \gsim 0.1 M$_J$ produce significant perturbations in the disc's surface density. The flow within the Roche lobe of the planet is fully three-dimensional. Gas streams generally enter the Roche lobe close to the disc midplane, but produce much weaker shocks than the streams in two-dimensional models. The streams supply material to a circumplanetary disc that rotates in the same sense as the planet's orbit. Much of the mass supply to the circumplanetary disc comes from non-coplanar flow. The accretion rate peaks with a planet mass of approximately 0.1 M$_J$ and is highly efficient, occurring at the local viscous rate. The migration timescales for planets of mass less than 0.1 M$_J$, based on torques from disc material outside the planets' Roche lobes, are in excellent agreement with the linear theory of Type I (non-gap) migration for three-dimensional discs. The transition from Type I to Type II (gap) migration is smooth, with changes in migration times of about a factor of 2. Starting with a core which can undergo runaway growth, a planet can gain up to a few M$_J$ with little migration. Planets with final masses of order 10 M$_J$ would undergo large migration, which makes formation and survival difficult.Comment: Accepted by MNRAS, 18 pages, 13 figures (6 degraded resolution). Paper with high-resolution figures available at http://www.astro.ex.ac.uk/people/mbate