Compact 20-kiloampere pulse-forming-network capacitor bank

Bank uses commercially available high-energy-density capacitors for energy storage and silicon-controlled rectifiers for switching. Low voltage design employing solid-state switching is utilized in lieu of conventional gas discharge switching

On the dynamical behavior of the ABC model

We consider the ABC dynamics, with equal density of the three species, on the discrete ring with $N$ sites. In this case, the process is reversible with respect to a Gibbs measure with a mean field interaction that undergoes a second order phase transition. We analyze the relaxation time of the dynamics and show that at high temperature it grows at most as $N^2$ while it grows at least as $N^3$ at low temperature

Search for Periodic Gravitational Wave Sources with the Explorer Detector

We have developped a procedure for the search of periodic signals in the data of gravitational wave detectors. We report here the analysis of one year of data from the resonant detector Explorer, searching for pulsars located in the Galactic Center (GC). No signals with amplitude greater than $\bar{h}= 2.9~10^{-24}$, in the range 921.32-921.38 Hz, were observed using data collected over a time period of 95.7 days, for a source located at $\alpha=17.70 \pm 0.01$ hours and $\delta=-29.00 \pm 0.05$ degrees. Our procedure can be extended for any assumed position in the sky and for a more general all-sky search, even with a frequency correction at the source due to the spin-down and Doppler effects.Comment: One zipped file (Latex+eps figures). 33 pages, 14 figures. This and related material also at http://grwav3.roma1.infn.it

Microservice Transition and its Granularity Problem: A Systematic Mapping Study

Microservices have gained wide recognition and acceptance in software industries as an emerging architectural style for autonomic, scalable, and more reliable computing. The transition to microservices has been highly motivated by the need for better alignment of technical design decisions with improving value potentials of architectures. Despite microservices' popularity, research still lacks disciplined understanding of transition and consensus on the principles and activities underlying "micro-ing" architectures. In this paper, we report on a systematic mapping study that consolidates various views, approaches and activities that commonly assist in the transition to microservices. The study aims to provide a better understanding of the transition; it also contributes a working definition of the transition and technical activities underlying it. We term the transition and technical activities leading to microservice architectures as microservitization. We then shed light on a fundamental problem of microservitization: microservice granularity and reasoning about its adaptation as first-class entities. This study reviews state-of-the-art and -practice related to reasoning about microservice granularity; it reviews modelling approaches, aspects considered, guidelines and processes used to reason about microservice granularity. This study identifies opportunities for future research and development related to reasoning about microservice granularity.Comment: 36 pages including references, 6 figures, and 3 table

An algebraic scheme associated with the noncommutative KP hierarchy and some of its extensions

A well-known ansatz (`trace method') for soliton solutions turns the equations of the (noncommutative) KP hierarchy, and those of certain extensions, into families of algebraic sum identities. We develop an algebraic formalism, in particular involving a (mixable) shuffle product, to explore their structure. More precisely, we show that the equations of the noncommutative KP hierarchy and its extension (xncKP) in the case of a Moyal-deformed product, as derived in previous work, correspond to identities in this algebra. Furthermore, the Moyal product is replaced by a more general associative product. This leads to a new even more general extension of the noncommutative KP hierarchy. Relations with Rota-Baxter algebras are established.Comment: 59 pages, relative to the second version a few minor corrections, but quite a lot of amendments, to appear in J. Phys.

Efectos de la endogamia en los rasgos fenotípicos en el caballo Hispano-Árabe

Our study investigates the influence of genetic parameters related to inbreeding in the Hispano-Arabian horse, focusing on coat color patterns. A total of 11,010 horses born between 1900 and 2019 were analyzed. Fourteen coat colors were studied: Chestnut/Sorrel, Black, Bay, Dun, Grey, Isabelline, Overo, Palomino, Cremello, Pearl, Piebald, Roan, Smokey Cream, and White. These coats were categorized into two groups: pure coats (Chestnut/ Sorrel, Bay and Black) and diluted coats (Dun, Grey, Isabelline, Cremello, Overo, Palomino, Pearl, Piebald, Roan, Smokey Cream, and White). Using Bayesian analysis, we determined that inbreeding levels are higher in pure coat colors compared to diluted ones. The highest average inbreeding value was found in the bay coat (4.5%), while the lowest values were observed in white and piebald coats (0%). These findings highlight the need for careful management of breeding programs to preserve genetic diversity and minimize inbreeding in the Hispano-Arabian horse

Antiangiogenic Tyrosine Kinase Inhibitors Have Differential Efficacy in Clear Cell Renal Cell Carcinoma in Bone

Clear cell renal cell carcinoma (ccRCC) is the most prevalent kidney neoplasm; bone metastasis (BM) develops in 35% to 40% of metastatic patients and results in substantial morbidity and mortality, as well as medical costs. A key feature of ccRCC is the loss of function of the von Hippel-Lindau protein, which enhances angiogenesis via vascular endothelial growth factor release. Consequently, antiangiogenic tyrosine kinase inhibitors (TKI) emerged as a treatment for ccRCC. However, limited data about their efficacy in BM is available, and no systematic comparisons have been performed. We developed mouse models of bone and lung ccRCC tumors and compared their anticancer efficacy, impact on mouse survival, and mechanisms of action, including effects on tumor cells and both immune and nonimmune (blood vessels and osteoclasts) bone stromal components. This approach elucidates the efficacy of TKIs in ccRCC bone tumors to support rational interrogation and development of therapies. Significance: TKIs showed different efficacy in synchronous bone and lung metastases and did not eradicate tumors as single agents but induced extensive reprogramming of the BM microenvironment. This resulted in a significant decrease in neoangiogenic blood vessels, bone remodeling, and immune cell infiltration (including CD8 T cells) with altered spatial distribution

The Simons Observatory: science goals and forecasts for the enhanced Large Aperture Telescope

We describe updated scientific goals for the wide-field, millimeter-wave survey that will be produced by the Simons Observatory (SO). Significant upgrades to the 6-meter SO Large Aperture Telescope (LAT) are expected to be complete by 2028, and will include a doubled mapping speed with 30,000 new detectors and an automated data reduction pipeline. In addition, a new photovoltaic array will supply most of the observatory's power. The LAT survey will cover about 60% of the sky at a regular observing cadence, with five times the angular resolution and ten times the map depth of the Planck satellite. The science goals are to: (1) determine the physical conditions in the early universe and constrain the existence of new light particles; (2) measure the integrated distribution of mass, electron pressure, and electron momentum in the late-time universe, and, in combination with optical surveys, determine the neutrino mass and the effects of dark energy via tomographic measurements of the growth of structure at redshifts z ≲ 3; (3) measure the distribution of electron density and pressure around galaxy groups and clusters, and calibrate the effects of energy input from galaxy formation on the surrounding environment; (4) produce a sample of more than 30,000 galaxy clusters, and more than 100,000 extragalactic millimeter sources, including regularly sampled AGN light-curves, to study these sources and their emission physics; (5) measure the polarized emission from magnetically aligned dust grains in our Galaxy, to study the properties of dust and the role of magnetic fields in star formation; (6) constrain asteroid regoliths, search for Trans-Neptunian Objects, and either detect or eliminate large portions of the phase space in the search for Planet 9; and (7) provide a powerful new window into the transient universe on time scales of minutes to years, concurrent with observations from the Vera C. Rubin Observatory of overlapping sky

The Simons Observatory: science goals and forecasts for the enhanced Large Aperture Telescope

We describe updated scientific goals for the wide-field, millimeter-wave survey that will be produced by the Simons Observatory (SO). Significant upgrades to the 6-meter SO Large Aperture Telescope (LAT) are expected to be complete by 2028, and will include a doubled mapping speed with 30,000 new detectors and an automated data reduction pipeline. In addition, a new photovoltaic array will supply most of the observatory's power. The LAT survey will cover about 60% of the sky at a regular observing cadence, with five times the angular resolution and ten times the map depth of Planck. The science goals are to: (1) determine the physical conditions in the early universe and constrain the existence of new light particles; (2) measure the integrated distribution of mass, electron pressure, and electron momentum in the late-time universe, and, in combination with optical surveys, determine the neutrino mass and the effects of dark energy via tomographic measurements of the growth of structure at z < 3; (3) measure the distribution of electron density and pressure around galaxy groups and clusters, and calibrate the effects of energy input from galaxy formation on the surrounding environment; (4) produce a sample of more than 30,000 galaxy clusters, and more than 100,000 extragalactic millimeter sources, including regularly sampled AGN light-curves, to study these sources and their emission physics; (5) measure the polarized emission from magnetically aligned dust grains in our Galaxy, to study the properties of dust and the role of magnetic fields in star formation; (6) constrain asteroid regoliths, search for Trans-Neptunian Objects, and either detect or eliminate large portions of the phase space in the search for Planet 9; and (7) provide a powerful new window into the transient universe on time scales of minutes to years, concurrent with observations from Rubin of overlapping sky