Generalized Hot Enhancons

We review what has been learnt and what remains unknown about the physics of hot enhancons following studies in supergravity. We recall a rather general family of static, spherically symmetric, non-extremal enhancon solutions describing D4 branes wrapped on K3 and discuss physical aspects of the solutions. We embed these solutions in the six dimensional supergravity describing Type IIA strings on K3 and generalize them to have arbitrary charge vector. This allows us to demonstrate the equivalence with a known family of hot fractional D0 brane solutions, to widen the class of solutions of this second type and to carry much of the discussion across from the D4 brane analysis. In particular we argue for the existence of a horizon branch for these branes.Comment: 25 pages, Late

A Systematic Review of the Efficacy of Motivational Interviewing on Occupational Performance

This systematic review aims to review the efficacy of MI to address such performance goals falling within the occupational therapy scope of practice

Efficacy of alternative seating on attention, in-seat behavior, and occupational performance in children with Attention Deficit Hyperactivity Disorder

Currently, there is one systematic review conducted by Gochenour and Poskey7 that synthesize current research evidence regarding alternative seating for students with attention difficulties. A limitation of this review, as noted by the authors, is a lack of a consistent definition of attention difficulty in the studies they included. A systematic review focused on a specific, well-defined diagnosis will better contribute to practice recommendations since these recommendations will be tailored to a clear and comprehensive understanding of the child’s attentional and occupational challenges. The review also included studies of children with autism spectrum disorder (ASD).7 While those with ASD may also have difficulties with attention, in-seat behavior and occupational performance, the underlying mechanism yielding these symptoms may be different than in children with ADHD. Thus, alternative seating may not work in the same way for children with ASD as it would for children with ADHD.7 Thus, a systematic review is needed to examine the evidence from all current studies regarding alternative seating on improving attention, in-seat behavior and occupational performance in students with ADHD to increase evidence-based practice in the field of occupational therapy

A Systematic Review: Light Therapy for Individuals with Dementia and Implications for Practice

This systematic review seeks to answer the question: is light therapy an effective intervention for sundowning symptoms experienced by individuals who have dementia

Interface Tension in Quenched QCD

We calculate the tension $\sigma$ of the interface between the confined and deconfined phases by the histogram method in SU(3) lattice gauge theory for temporal extents of 4 and 6 using the recent high-statistics data by QCDPAX collaboration. The results are $\sigma/T_c^3 = 0.0292(22)$ and 0.0218(33) for $N_t=4$ and 6, respectively. The ratio $\sigma/T_c^3$ shows a scaling violation similar to that already observed for the latent heat \latent. However, we find that the physically interesting dimensionless combinations (\sigma^{3}/\latent^2 T)^{1/2} and \sigma T/ \latent scale within the statistical errors.Comment: 13 pages with 2 PostScript figures, LaTeX, CERN-TH.6798/93, AZPH-TH/93-04, UTHEP-25

TLR7-mediated skin inflammation remotely triggers chemokine expression and leukocyte accumulation in the brain

Background: The relationship between the brain and the immune system has become increasingly topical as, although it is immune-specialised, the CNS is not free from the influences of the immune system. Recent data indicate that peripheral immune stimulation can significantly affect the CNS. But the mechanisms underpinning this relationship remain unclear. The standard approach to understanding this relationship has relied on systemic immune activation using bacterial components, finding that immune mediators, such as cytokines, can have a significant effect on brain function and behaviour. More rarely have studies used disease models that are representative of human disorders. Methods: Here we use a well-characterised animal model of psoriasis-like skin inflammation—imiquimod—to investigate the effects of tissue-specific peripheral inflammation on the brain. We used full genome array, flow cytometry analysis of immune cell infiltration, doublecortin staining for neural precursor cells and a behavioural read-out exploiting natural burrowing behaviour. Results: We found that a number of genes are upregulated in the brain following treatment, amongst which is a subset of inflammatory chemokines (CCL3, CCL5, CCL9, CXCL10, CXCL13, CXCL16 and CCR5). Strikingly, this model induced the infiltration of a number of immune cell subsets into the brain parenchyma, including T cells, NK cells and myeloid cells, along with a reduction in neurogenesis and a suppression of burrowing activity. Conclusions: These findings demonstrate that cutaneous, peripheral immune stimulation is associated with significant leukocyte infiltration into the brain and suggest that chemokines may be amongst the key mediators driving this response

The quantum structure of black holes

We give an elementary review of black holes in string theory. We discuss black hole entropy from string microstates and Hawking radiation from these states. We then review the structure of 2-charge microstates, and explore how `fractionation' can lead to quantum effects over macroscopic length scales of order the horizon radius.Comment: Review article, 58 pages, 2 figures; references added, note about topics covere

Effects of Slotted Water Control Structures on Nekton Movement within Salt Marshes

Water control structures (WCSs) restrict hydrological connectivity in salt marshes and thereby impede nekton movement within the greater habitat mosaic. Transient fishery species, which spawn outside salt marshes and must get past these barriers to reach spawning areas or salt-marsh nurseries, are especially vulnerable to these structures. Water control structures incorporating slots (narrow vertical openings spanning most of the water column) are thought to improve nekton passage; however, few studies have directly examined nekton passage through WCS slots. Dual-frequency identification sonar (DIDSON) acoustic imaging was used monthly (April-September 2010) on diurnal flood tides to examine nekton movement through 15-cm-wide slots at two identical WCSs located in Louisiana tidal marsh channels. Nekton behavior was compared between these WCSs and a nearby natural salt-marsh creek. Examination of 12 h of subsampled acoustic data revealed large concentrations of salt-marsh nekton at the WCSs (n = 2,970 individuals total), but passage rates through the slots were low (\u3c= 10% of total observed individuals migrated via the slots). Most migrating fish were observed leaving the managed area and swimming against a flood tide. The mean size of migrating individuals (similar to 25 cm TL) did not differ in relation to swimming direction (going into versus exiting the managed marsh) and was similar to that reported from other studies examining similar slot widths. Nekton formed congregations in the WCS channel, but no congregations were observed in the natural salt-marsh creek, even though nekton species composition and sizes were similar among sites. The WCSs in our study appear to function as ecological hot spots, where large individuals may encounter enhanced foraging opportunities but also fishing mortality and where smaller individuals may experience greater predation rates

Contributions of a global network of tree diversity experiments to sustainable forest plantations

The area of forest plantations is increasing worldwide helping to meet timber demand and protect natural forests. However, with global change, monospecific plantations are increasingly vulnerable to abiotic and biotic disturbances. As an adaption measure we need to move to plantations that are more diverse in genotypes, species, and structure, with a design underpinned by science. TreeDivNet, a global network of tree diversity experiments, responds to this need by assessing the advantages and disadvantages of mixed species plantations. The network currently consists of 18 experiments, distributed over 36 sites and five ecoregions. With plantations 1–15 years old, TreeDivNet can already provide relevant data for forest policy and management. In this paper, we highlight some early results on the carbon sequestration and pest resistance potential of more diverse plantations. Finally, suggestions are made for new, innovative experiments in understudied regions to complement the existing network

TRY plant trait database - enhanced coverage and open access

Plant traits-the morphological, anatomical, physiological, biochemical and phenological characteristics of plants-determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait-based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits-almost complete coverage for 'plant growth form'. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait-environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives