Role of clobetasol propionate 0.025% topical therapy in various dermatoses

The anti-inflammatory and vasoconstrictive properties of topical corticosteroids (TCs) contribute in providing therapeutic benefits in several skin conditions, including atopic eczema, localized vitiligo, psoriasis, and chronic hand eczema. Clobetasol propionate (CP) is the most common topical agent used for psoriasis management and demonstrates an efficacy superior to other TCs. A new CP 0.025% cream formulation has demonstrated hypoallergenic effects due to the absence of known contact allergens, such as propylene glycol, short-chain alcohols, and sorbitol-based emulsifiers. Lower CP serum levels and less hypothalamic–pituitary–adrenal axis suppression with CP 0.025% cream formulation than with CP 0.05% ensure better safety. The present case series discusses the clinical experience of using CP 0.025% cream in various dermatological conditions

Spectrum of sensitive skin in India: a collaborative expert position statement

IntroductionSensitive skin poses a significant dermatological concern in India, influenced by diverse climatic conditions, cultural practices, and pollution levels. These factors contribute to the prevalence of sensitive skin, which is characterized by symptoms such as redness, itching, and dryness. Sensitive skin is better understood as a distinct syndrome rather than a linear progression from dry skin to conditions like acne, atopic dermatitis, and rosacea. The condition impacts the overall quality of life of affected individuals, making it crucial to understand its spectrum and management.MethodsA panel of 12 dermatologists from various regions of India provided expert insights into the characterization of sensitive skin. The dermatologists discussed the spectrum of sensitive skins and provided strategies for managing the condition. Their recommendations emphasized the importance of individualized skincare regimens tailored to the specific needs of patients.ResultsSeveral studies have discussed the heterogeneity of sensitive skin, indicating the complexity of its diagnosis and management. The market is saturated with a variety of cosmeceuticals aimed at addressing sensitive skin. However, there are no established guidelines for using these products, leading to the adoption of individualized skincare regimens as the most common approach.DiscussionThis expert paper highlights the necessity of recommending cosmeceuticals in managing sensitive skin and emphasizes the importance of personalized skincare regimens. By comprehensively addressing the spectrum of sensitive skin, clinicians can prevent the progression to severe dermatological conditions, thereby safeguarding the skin barrier and improving the overall quality of life for individuals affected by sensitive skin

Role of clobetasol propionate 0.025% topical therapy in various dermatoses

The anti-inflammatory and vasoconstrictive properties of topical corticosteroids (TCs) contribute in providing therapeutic benefits in several skin conditions, including atopic eczema, localized vitiligo, psoriasis, and chronic hand eczema. Clobetasol propionate (CP) is the most common topical agent used for psoriasis management and demonstrates an efficacy superior to other TCs. A new CP 0.025% cream formulation has demonstrated hypoallergenic effects due to the absence of known contact allergens, such as propylene glycol, short-chain alcohols, and sorbitol-based emulsifiers. Lower CP serum levels and less hypothalamic–pituitary–adrenal axis suppression with CP 0.025% cream formulation than with CP 0.05% ensure better safety. The present case series discusses the clinical experience of using CP 0.025% cream in various dermatological conditions.</jats:p