Binary Structuring Elements Decomposition Based on an Improved Recursive Dilation-Union Model and RSAPSO Method

This paper proposed an improved approach to decompose structuring elements of an arbitrary shape. For the model of this method, we use an improved dilation-union model, adding a new termination criterion, as the sum of 3-by-3 matrix should be less than 5. Next for the algorithm of this method, we introduced in the restarted simulated annealing particle swarm optimization method. The experiments demonstrate that our method can find better results than Park's method, Anelli's method, Shih's SGA method, and Zhang's MFSGA method. Besides, our method gave the best decomposition tree of different SE shapes including “ship,” “car,” “heart,” “umbrella,” “vase,” “tree,” “cat,” “V,” “bomb,” and “cup.

Tea Category Identification Using a Novel Fractional Fourier Entropy and Jaya Algorithm

This work proposes a tea-category identification (TCI) system, which can automatically determine tea category from images captured by a 3 charge-coupled device (CCD) digital camera. Three-hundred tea images were acquired as the dataset. Apart from the 64 traditional color histogram features that were extracted, we also introduced a relatively new feature as fractional Fourier entropy (FRFE) and extracted 25 FRFE features from each tea image. Furthermore, the kernel principal component analysis (KPCA) was harnessed to reduce 64 + 25 = 89 features. The four reduced features were fed into a feedforward neural network (FNN). Its optimal weights were obtained by Jaya algorithm. The 10 × 10-fold stratified cross-validation (SCV) showed that our TCI system obtains an overall average sensitivity rate of 97.9%, which was higher than seven existing approaches. In addition, we used only four features less than or equal to state-of-the-art approaches. Our proposed system is efficient in terms of tea-category identification

Comment on “An Investigation into the Performance of Particle Swarm Optimization with Various Chaotic Maps”

This paper researched three definitions of Gauss map and found that the definition of “Gauss map” in the paper of Arasomwan and Adewumi may be incoherent with other publications. In addition, we analyzed the difference of continuous Gauss map and the floating-point Gauss map, and we pointed out that the floating-point simulation behaved significantly differently from the continuous Gauss map

Multiple Sclerosis Identification by 14-Layer Convolutional Neural Network With Batch Normalization, Dropout, and Stochastic Pooling

Aim: Multiple sclerosis is a severe brain and/or spinal cord disease. It may lead to a wide range of symptoms. Hence, the early diagnosis and treatment is quite important.Method: This study proposed a 14-layer convolutional neural network, combined with three advanced techniques: batch normalization, dropout, and stochastic pooling. The output of the stochastic pooling was obtained via sampling from a multinomial distribution formed from the activations of each pooling region. In addition, we used data augmentation method to enhance the training set. In total 10 runs were implemented with the hold-out randomly set for each run.Results: The results showed that our 14-layer CNN secured a sensitivity of 98.77 ± 0.35%, a specificity of 98.76 ± 0.58%, and an accuracy of 98.77 ± 0.39%.Conclusion: Our results were compared with CNN using maximum pooling and average pooling. The comparison shows stochastic pooling gives better performance than other two pooling methods. Furthermore, we compared our proposed method with six state-of-the-art approaches, including five traditional artificial intelligence methods and one deep learning method. The comparison shows our method is superior to all other six state-of-the-art approaches

Duration of androgen deprivation therapy with postoperative radiotherapy for prostate cancer: a comparison of long-course versus short-course androgen deprivation therapy in the RADICALS-HD randomised trial

Background Previous evidence supports androgen deprivation therapy (ADT) with primary radiotherapy as initial treatment for intermediate-risk and high-risk localised prostate cancer. However, the use and optimal duration of ADT with postoperative radiotherapy after radical prostatectomy remains uncertain. Methods RADICALS-HD was a randomised controlled trial of ADT duration within the RADICALS protocol. Here, we report on the comparison of short-course versus long-course ADT. Key eligibility criteria were indication for radiotherapy after previous radical prostatectomy for prostate cancer, prostate-specific antigen less than 5 ng/mL, absence of metastatic disease, and written consent. Participants were randomly assigned (1:1) to add 6 months of ADT (short-course ADT) or 24 months of ADT (long-course ADT) to radiotherapy, using subcutaneous gonadotrophin-releasing hormone analogue (monthly in the short-course ADT group and 3-monthly in the long-course ADT group), daily oral bicalutamide monotherapy 150 mg, or monthly subcutaneous degarelix. Randomisation was done centrally through minimisation with a random element, stratified by Gleason score, positive margins, radiotherapy timing, planned radiotherapy schedule, and planned type of ADT, in a computerised system. The allocated treatment was not masked. The primary outcome measure was metastasis-free survival, defined as metastasis arising from prostate cancer or death from any cause. The comparison had more than 80% power with two-sided α of 5% to detect an absolute increase in 10-year metastasis-free survival from 75% to 81% (hazard ratio [HR] 0·72). Standard time-to-event analyses were used. Analyses followed intention-to-treat principle. The trial is registered with the ISRCTN registry, ISRCTN40814031, and ClinicalTrials.gov , NCT00541047 . Findings Between Jan 30, 2008, and July 7, 2015, 1523 patients (median age 65 years, IQR 60–69) were randomly assigned to receive short-course ADT (n=761) or long-course ADT (n=762) in addition to postoperative radiotherapy at 138 centres in Canada, Denmark, Ireland, and the UK. With a median follow-up of 8·9 years (7·0–10·0), 313 metastasis-free survival events were reported overall (174 in the short-course ADT group and 139 in the long-course ADT group; HR 0·773 [95% CI 0·612–0·975]; p=0·029). 10-year metastasis-free survival was 71·9% (95% CI 67·6–75·7) in the short-course ADT group and 78·1% (74·2–81·5) in the long-course ADT group. Toxicity of grade 3 or higher was reported for 105 (14%) of 753 participants in the short-course ADT group and 142 (19%) of 757 participants in the long-course ADT group (p=0·025), with no treatment-related deaths. Interpretation Compared with adding 6 months of ADT, adding 24 months of ADT improved metastasis-free survival in people receiving postoperative radiotherapy. For individuals who can accept the additional duration of adverse effects, long-course ADT should be offered with postoperative radiotherapy. Funding Cancer Research UK, UK Research and Innovation (formerly Medical Research Council), and Canadian Cancer Society