MQTT and ROC Based Hybrid Robot as a Service (RaaS) Platform

Robots are rapidly evolving from factory work-horses to robot-companions. The future of robots will be as companions in the workplace functioning as interactive salespeople. In order to support this transition, it is important to combine service-oriented architecture and robotics. Service-oriented architecture and cloud computing have become dominant computing paradigms, and adding an RaaS (Robot as a Service) unit as a part of this system will help the companies manage and develop robots more efficiently. The major components of RaaS will be the integration of RMS (Robot Management System) and ROC (Robot Operation Center). As more and more robots are increasing in the service industry, the inter-robot communication is very critical. This communication can be achieved by ROC and the robots can be monitored remotely or locally via RMS. The RaaS platform will comply with all the standards of SOA (Service Oriented Architecture) like the development platform and execution unit, thereby creating a flexible and more development-friendly process

Complex Multifunctional Polymer/Carbon-Nanotube Composites

A methodology for developing complex multifunctional materials that consist of or contain polymer/carbon-nanotube composites has been conceived. As used here, "multifunctional" signifies having additional and/or enhanced physical properties that polymers or polymer-matrix composites would not ordinarily be expected to have. Such properties include useful amounts of electrical conductivity, increased thermal conductivity, and/or increased strength. In the present methodology, these properties are imparted to a given composite through the choice and processing of its polymeric and CNT constituents

RELATIVE QUANTITATION OF PEPTIDES BY INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY

Currently, the detection/quantitation of biomolecules using Inductively Coupled Plasma Mass Spectrometry (ICR-MS) is focused on heteroatom containing (e.g. S. P, Se, Cu) compounds. This limits the scope of ICP-MS as a routine analytical tool in the bioanalytical sciences. To increase this scope novel strategies to incorporate elemental labels have been developed. Chemical derivatisation is one such strategy. Cyclic diethylenetriaminepentaacetic acid anhydride (cDTPA), a bifunctional chelating agent (BFCA), is reacted with N-terminal amines and is subsequently chelated with trivalent metals. This allows the detection of peptides that contained no heteroatom using liquid chromatography (LC)-ICP-MS. The derivatisation efficiency, optimised using LC-UV/vis detection, is approximately 99%. The derivatisation and chelation reactions products are characterised using LC-electrospray ionisation tandem mass spectrometry (ESI-MS-MS). The labelling procedure allowed the relative quantitation of peptides, by differential isotopic labelling. Two individually derivatised peptide samples are chelated with natural isotopic abundance and isotopically enriched 151Eu respectively. The Eu labelled peptides were combined and analysed by LC-ICP-MS. The resulting 153EU:151EU ratio, measured using the pseudo steady state approach for transient signals; is then used to calculate the original peptide proportions using a modified isotope dilution equation. The ICP-MS measured peptide ratio was within 2.8% of the theoretical peptide ratio. The absolute detection limit for the relative quantitation of Eu labelled bradykinin was 5 pmol, which is comparable to current ESI-MS methods. When cDTPA derivatisation was applied to a complex sample multiple by-products were observed in the LC-UV/vis chromatogram. However, the corresponding LC-ICP-MS chromatogram suggested that only singly derivatised peptides were chelated with the metal. To overcome by-product formation monoreactive BFCAs, namely isothiocyanate-benzyl- EDTA (SCN-Bz-EDTA) and isothiocyanate-benzyl-DTPA (SCN-Bz-DTPA). were evaluated as derivatisation reagents. Solid phase analytical derivatisation (SPAD) and solid phase extraction (SPE) were also evaluated for speed and ease of use. The monoreactive nature of SCN-Bz-EDTA and SCN-Bz-DTPA gave singly derivatised peptides when applied to complex samples. However, the resulting derivatisation efficiency was low and no significant improvement in efficiency was noted when SPAD was used. SCN-Bz-EDTA derivatised peptides could not be chelated to trivalent metals, whilst chelation occurred with SCN-Bz-DTPA derivatised peptides. Eu labelled peptides were isolated and selectively extracted by SPE for relative quantitation by LC-ICP-MS. However, due to the instability of the isothiocyanate reagent and instrumental effects the relative error on the measured peptide ratio was greater than 45% when compared to the theoretical ratio. Although the peptide ratio obtained using the SPE method agreed with the ratio from the non extracted sample

A study of access and compliance of iron and folic acid tablets for prevention and cure of anaemia among adolescent age group females in Ahmedabad district of India surveyed under multi indicator cluster survey 2011

Objective The knowledge and utilization of Iron and folic acid tablets supplementation of the adolescent girls in Ahmedabad district. Setting The study was conducted over a time span of 20 weeks period, from April 2011 till Aug 2011 in selected areas of Ahmedabad district, which has an approximate population of 15,94,010 as per census 2001. Study design Cross sectional observational study. Participants All the adolescent girls in the population surveyed by MICS 2011. Methodology 30 clusters sampling method based on PPS (Probability Proportional to Size) for cluster selection. Results 431 adolescent girls were included in the survey of total population of 6076. The result showed that 51.5% (222) girls went to school and only 36.2% (156) received IFA tablets. Out of them 66% (103) girls stopped taking these tablets due to one or other side effects of the tablets. Nearly 47.4% (74) girls were unaware of the positive effects of these tablets on their health

Strength Training to Enhance Early Recovery after Hematopoietic Stem Cell Transplantation

Intensive cancer treatment followed by hematopoietic stem cell transplantation (HCT) results in moderate to severe fatigue and physical inactivity, leading to diminished functional ability. The purpose of this study was to determine the efficacy of an exercise intervention, strength training to enhance early recovery (STEER), on physical activity, fatigue, muscle strength, functional ability, and quality of life after HCT. This single-blind, randomized clinical trial compared strength training (n = 33) to usual care plus attention control with health education (UC + AC with HE) (n = 34). Subjects were stratified by type of transplantation and age. STEER consisted of a comprehensive program of progressive resistance introduced during hospitalization and continued for 6 weeks after hospital discharge. Fatigue, physical activity, muscle strength, functional ability, and quality of life were assessed before HCT hospital admission and after intervention completion. Data were analyzed using split-plot analysis of variance. Significant time × group interactions effects were noted for fatigue (P = .04). The STEER group reported improvement in fatigue from baseline to after intervention whereas the UC + AC with HE group reported worsened fatigue from baseline to after intervention. Time (P < .001) and group effects (P = .05) were observed for physical activity. Physical activity declined from baseline to 6 weeks after hospitalization. The STEER group was more physically active. Functional ability tests (timed stair climb and timed up and go) resulted in a significant interaction effect (P = .03 and P = .05, respectively). Subjects in the UC + AC with HE group were significantly slower on both tests baseline to after intervention, whereas the STEER group's time remained stable. The STEER group completed both tests faster than the UC + AC with HE group after intervention. Study findings support the use of STEER after intensive cancer treatment and HCT. Strength training demonstrated positive effects on fatigue, physical activity, muscle strength, and functional ability. The exact recovery patterns between groups and over time varied; the STEER group either improved or maintained their status from baseline to after intervention (6 weeks after hospital discharge) whereas the health education group generally declined over time or did not change

Identification and Parsing of SQL Query Command by Implementation of JSON

In today’s world mobile devices have become a necessity for many people. These devices have ability to keep in touch with family members and business partners. It is also used to share information in real time.But some time people don’t like to input text on a small mobile device which may lead to error, compared to text input via full-sized keyboard on desktop computer system. In this paper we are going to present how SQL database query can be input using voice and technically parsed using JSON data storage. Here we use Pocketsphinx for Android and Google voice API to convert speech to text and create database query by processing text which return SQL query by processing JSON

DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR DETERMINATION OF HYDROCHLOROTHIAZIDE, OLMESARTAN MEDOXOMIL AND THEIR RELATED SUBSTANCES IN COMBINED TABLET DOSAGE FORM

Objective: Development of RP-HPLC method for determination of Hydrochlorothiazide (HCTZ), Olmesartan medoxomil (OLM) and their related substances in combined tablet dosage form and validation of the developed method. Methods: Gradient mobile phase system was used for estimation of drug contents and their related substances. Mobile phase A contained the mixture of Acetonitrile and 15 mM Phosphate buffer (pH adjusted to 3.4 with orthophosphoric acid) in the ratio of 20:80. Mobile phase B contained the same mixture in the ratio of 80:20. Chromatographic separation was carried out at the mobile phase flow rate of 0.8 mL/min using C18 Phenomenax inplace of Enable (250 × 4.6 mm) 5 μm column and detection was made at 254 nm. Results: The linearity of developed method was tested in the range of 62.5-187.5 μg/mL for Hydrochlorothiazide, 100-300 μg/mL for Olmesartan medoxomil, 1-1.8 μg/mL for Hydrochlorothiazide. The % recovery was found to be 99.88-100.67 % (HCTZ), 99.14-99.91 % (OLM), 99.11-100.71% (HCTZ-IMP) and 98.13-100.83% (OLM-IMP). The assay of marketed formulation was found to be 99.78% (HCTZ) and 99.26% (OLM). Conclusion: A simple, precise and accurate RP-HPLC method was developed for determination of Hydrochlorothiazide, Olmesartan medoxomil and their related substances

Antioxidative and physiological studies onColocasia esculentum in response to arsenic stress

The current study was undertaken to determine the effects of arsenic on Colocasia esculentum. Rhizomes were grown in pots containing 2.5 kg of garden soil with increasing concentration of arsenic. Arsenic  accumulation was more in shoots compared to roots at higher concentrations. High arsenic concentration  caused reduction in plant growth along with induction of few antioxidants. C. esculentum has a strong  antioxidative and physiological defense mechanism. Under arsenic stress, an increase in catalase, peoxidase,  few non-enzymatic antioxidants and an induction of few stress induced protein were observed, along with  some anatomical changes in roots. The increase in antioxidant stress enzyme activities in response to arsenic  exposure may be taken as evidence for an enhanced detoxification capacity of C. esculentum, a  herbaceous monocot plant, towards reactive oxygen species (and derivatives) that might be generated in the stressed plants.Key words: Arsenic, Colocasia esculentum, antioxidant, metal, root

SYNTHESIS AND ANTIMICROBIAL SCREENING OF SOME IMIDAZOLIDINE DERIVATIVES OF ISONICOTINAMIDE

New series of N (2-alkyl/aryl-5-oxo-imidazolidine-1-yl) isonicotinamide derivatives were synthesized by the reaction of Schiff base with amino acetic acid in the presence of 1:4 dioxane. Synthesized compounds were evaluated for their Anti-bacterial activity against Staphylococcus aureus and Echerichia coli, Antifungal activity against Candida Albicans and Anti-tubercular activity against Mycobacterium tuberculosis. Synthesized compounds show significant activity against bacterial, fungal and mycobacterium strains. Their structures were established on the basis of elemental analysis, IR, 1H NMR and Mass Spectral data