Effect of probiotics fermentation on antioxidant property of oat milk

The live microorganisms which provide health benefits to our body by maintaining and enhancing the intestinal microbial balance are called probiotics. They are considered to be very useful for its effectiveness against a range of gastrointestinal diseases and disorders. A prebiotic is defined as a non digestible food ingredient that beneficially affects the host body by selectively stimulating the activity or growth of one or a limited number of bacteria in the colon and thus improves host health. A synbiotic is a combination of probiotics and prebiotics that beneficially affects the host by improving the survival of live microbial dietary supplements in the gastrointestinal tract. They stimulate the growth of health promoting bacteria. The microbiota management of probiotics, prebiotics and synbiotics have been developed and commercialized over the past few decades with the expressed need of increasing numbers of bifidobacteria and lactobacilli within the gastrointestinal tract. In the present work the antioxidant property of the synbiotic product made by fermentation of different probiotic strains and oats were studied. The prebiotic source oats was fermented with different strains of lactic acid bacteria to obtain a drink, combining the health benefits of probiotic culture with oat prebiotic beta glucan having antioxidant property. The antioxidant activity of the fermented oat product was studied by DPPH radical scavenging activity

The Role of Green Spaces in Mitigating Urban Heat Island Effects and Promoting Community Health

Introduction: This study aimed to explore how green spaces contribute to reducing urban heat island effects and enhancing public health. The heat island effect is the tendency for urban areas to be warmer than rural areas, leading to environmental and health consequences. Green spaces, including parks, gardens, and trees, may counteract some of these effects by providing shade and cooling and by encouraging residents of cities to be physically active and to enjoy better mental health.Methods: A literature review was made to collect information on the advantages of green spaces in cities. Past researches which explored how green spaces help to reduce urban heat island effects and increase community health were obtained and examined. They also looked at case studies of cities that have implemented such initiatives, and examined their efficacy.Results: The results of this study indicated that green spaces can be useful in reducing the urban heat island effect. Trees and other vegetation can lower surface temperatures in urban areas, provide shade, and enhance air quality. In addition, green spaces have been shown to contribute to community health by offering spaces for exercise, calming anxiety, and acting as a hub for socializing.Conclusions: To sum up, the findings of the study provide evidence that green spaces are crucial in reducing the negative impacts of urban heat islands and enhance the well-being of communities. Vertical gardening, terrace gardening, etc. This highlights the need for urban planners and policymakers to prioritize the development and preservation of green spaces in cities to counteract the negative effects of urbanization and foster healthy, sustainable communities

Delusional disorder of snake infestation – A diagnostic dilemma

Delusional infestation is a condition where one believes that he or she has a large parasitic infestation. We present a case with delusion of snake infestation as the only psychotic symptom without any primary psychotic or mood disorder. The site of infestation and the type of parasite involved makes it an unusual clinical presentation

An Examination of How Robots, Artificial Intelligence, and Machinery Learning are Being Applied in the Medical and Healthcare Industries

Machine learning techniques are associated with diagnostics systems to apply methods that enable computers to link patient data to earlier data and give instructions to correct the disease.In recent years, researchers have promoted two or three data mining based techniques for disease diagnosis. Each function in machine learning and data mining techniques is built through characteristics and features.As a part of prognosis, information must be separated from patient data and information retrieved in stored databases and comparative records. For any disease, early diagnosis or diagnosis will determine the chances of a correct recovery. Disease prediction therefore becomes a more important task to support physicians in delivering efficient treatment to people.In health care, data is being created and disposed of at an extraordinary rate compared to the health care sectors. Data for medical profiling is often found in a variety of sources such as electronic health records, lab and imaging systems, doctor notes and accounts. The medical records database will then contain irrelevant data sourced from multiple sources. Preprocessing data and eliminating irrelevant data then immediately opening it up for predictive analysis is one of the significant difficulties of the health care industry

Spinterface Mediated Magnetic Properties of Co20Fe60B20/Alq3 Heterostructures

Organic semiconductors (OSCs) are suitable materials for spintronics applications as they form a spinterface when placed next to a ferromagnet, which in turn leads to novel functionalities. The evolution of spinterface can tune the global magnetic anisotropy, magnetization reversal, magnetization dynamics, etc. Planar tris-(8-hydroxyquinoline)aluminum (Alq3) OSC has shown tremendous potential for spintronics applications, thanks to its efficient spin-polarized current transport ability. Here, we establish the spinterface when the Alq3 molecules are deposited on amorphous ferromagnet Co20Fe60B20(CFB). The $\pi$-d hybridization in CFB/Alq3 enhances the coercive field and significantly modifies the shape and size of the magnetic domains. A $\sim$100% increase in uniaxial anisotropic energies and a reduction in magnetic damping are also evident owing to the strong interfacial hybridization

PREVALENCE OF DIABETIC RETINOPATHY IN TYPE 2 DIABETES MELLITUS: AN OBSERVATIONAL STUDY IN SOUTHERN INDIA

  Objectives: In India, 69.1 million are diabetics as of 2015 compared to 18 million in 1995. Pan India prevalence study in diabetics carried out at 194 centers by All India Ophthalmological Society reported the prevalence of diabetic retinopathy (DR) among diabetics as 21.8%. DR is of two types, non-proliferative diabetic retinopathy (NPDR), and proliferative diabetic retinopathy (PDR). The severity of NPDR depends on microaneurysms, hemorrhages, cotton wool spots, and beading of veins and can progress to PDR. Inherit characteristic of PDR is neovascularization. The aim of this observational prevalence study is to study the prevalence of diabetic retinopathy in Type 2 diabetic patients attending diabetic clinic and to study the distribution of diabetic retinopathy with respect to age, sex, and duration of disease in a tertiary care hospital in southern India.Methods: This is a retrospective observational study. Age above 20 years and patients diagnosed with Type 2 diabetes mellitus (DM) and examined by the ophthalmologist were included and others excluded. Data documented were analyzed using statistical software SPSS version 16.Results: About 52.07% of patients with Type 2 DM for more than 10 years had diabetic retinopathy and 13.07 % of patients with Type 2 DM for more than 5 years have diabetic retinopathy.Conclusion: India being the diabetic capital of the world and DR being the most common cause for visual impairment and blindness and it becomes empirical to assess the factors for its rising prevalence, which will significantly contribute in reducing the progression of DR

Tensile and Flexural Properties of Chopped Strand E-glass Fibre Mat Reinforced CNSL-Epoxy Composites.

Glass fibres have the principal advantages such as high tensile strength, high chemical resistance, low cost, and excellent insulating properties which makes them an important constituent in fibre reinforced plastic and composite industry. In this study, E-glass fibre in the form of Chopped Strand Mat (CSM) with different weight fractions such as 15%, 30%, and 45% were used as reinforcement in CNSL-epoxy resin composites. Fabrication of the composites was done by hand layup technique. Micro-hardness, tensile and flexural properties were investigated for all the composite panels of different compositions. The results clearly indicated an improvement in micro hardness, tensile and flexural properties with the increase in fibre content

Informal Providers—Ground Realities in South Asian Association for Regional Cooperation Nations: Toward Better Cancer Primary Care: A Narrative Review

PurposeSouth Asian Association for Regional Cooperation (SAARC) nations are a group of eight countries with low to medium Human Development Index values. They lack trained human resources in primary health care to achieve the WHO-stated goal of Universal Health Coverage. An unregulated service sector of informal health care providers (IPs) has been serving these underserved communities. The aim is to summarize the role of IPs in primary cancer care, compare quality with formal providers, quantify distribution in urban and rural settings, and present the socioeconomic milieu that sustains their existence.MethodsA narrative review of the published literature in English from January 2000 to December 2021 was performed using MeSH Terms Informal Health Care Provider/Informal Provider and Primary Health Care across databases such as Medline (PubMed), Google Scholar, and Cochrane database of systematic reviews, as well as World Bank, Center for Global Development, American Economic Review, Journal Storage, and Web of Science. In addition, citation lists from the primary articles, gray literature in English, and policy blogs were included. We present a descriptive overview of our findings as applicable to SAARC.ResultsIPs across the rural landscape often comprise more than 75% of primary caregivers. They provide accessible and affordable, but often substandard quality of care. However, their network would be suitable for prompt cancer referrals. Care delivery and accountability correlate with prevalent standards of formal health care.ConclusionAcknowledgment and upskilling of IPs could be a cost-effective bridge toward universal health coverage and early cancer diagnosis in SAARC nations, whereas state capacity for training formal health care providers is ramped up simultaneously. This must be achieved without compromising investment in the critical resource of qualified doctors and allied health professionals who form the core of the rural public primary health care system

NANO-LM: An updated scorecard for the clinical assessment of patients with leptomeningeal metastases

Background There are no validated tools for the clinical neurological assessment of patients with leptomeningeal metastases (LM). However, clinical examination during the course of the disease guides medical management and is part of response assessment in clinical trials. Because neuroimaging may not always be obtained owing to rapid clinical deterioration, clinical neurological assessment of LM is essential, and standardization is important to minimize rater disagreement. Methods The Response Assessment in Neuro-oncology-LM group launched a 2-step process, aiming at improving and standardizing the clinical assessment of patients with LM. We report here on the first step the establishment of a consensus scorecard. The task force had 9 virtual meetings to define general recommendations on neurological assessment and selected domains of interest that should be tested. Results Fourteen domains of neurological symptoms and signs were selected: level of consciousness, cognition, nausea and vomiting, vision, eye movement, facial strength, hearing, swallowing, speech, limb strength, limb ataxia, walking, and bladder bowel functions. For each item, a clear instruction on how to perform the assessment is provided with scoring criteria between 0 and 2. The general clinical status of the patient and use of steroids, pain medications, and antiemetics should be documented. Neurological sequelae from previous brain metastases or cancer treatment should be rated at the baseline evaluation; it should be specified when symptoms or signs may be related to a condition other than LM. Discussion A revised Neurological Assessment in Neuro-Oncology-LM consensus scorecard for clinical assessment has been established. An international prospective validation study of the proposal is currently ongoing (NCT06417710)

Histopathological spectrum of lesions of upper gastrointestinal tract – A study of endoscopic biopsies

Background: Gastrointestinal (GI) disorders are one of the most commonly encountered health problems in routine clinical practice. Dietary, environmental, geographic, and genetic factors are some of the key reasons contributing to the prevalence of these diseases. A wide spectrum of lesions is observed on histopathological examination of the upper GI tract (GIT). Aims and Objective: The study was carried out to determine the histopathological spectrum of upper GIT lesions and to compare the lesions with demographic and clinical data. Materials and Methods: The study was conducted on all consecutive upper GI endoscopic biopsies received in the Department of Pathology, Narendra Modi Medical College, Ahmedabad during the period from August 2020 to October 2022. Results: Non-neoplastic lesions were observed in 91.3% of all upper GI biopsies. Among these, gastric lesions (63.3%) were the most common followed by duodenal lesions (21.3%) and esophageal lesions (6.6%). The most commonly observed non-neoplastic lesions from the esophagus, stomach, and duodenum were reflux esophagitis with its consequence Barrett’s esophagus, chronic gastritis, and chronic duodenitis, respectively. Neoplastic lesions were observed in 8.7% of all upper GI biopsies; out of which 4% were esophageal, 3.3% were gastric and 1.3% were duodenal. The most commonly observed neoplastic lesions from the esophagus, stomach, and duodenum were squamous cell carcinoma of the esophagus, adenocarcinoma of the stomach, and adenocarcinoma of duodenum, respectively. Conclusion: Endoscopic biopsy examination followed by histopathologic assessment is a convenient procedure and current gold standard for the accurate diagnosis of patients with upper GIT lesions