Pressure Pump Power Control in the Primary Circuit of the Heat Exchange System

In this paper we consider the problem of speed in hot water systems where highly efficient plate heat exchanger is used. Especially marked the problem which is connected with long transition drive of constant speed exceeding the time of the heat exchanger accumulative tank emptying more than twice. As a regulating element in the heat exchange system there was proposed to use asynchronous electric drive of pressure pump in the primary circuit of the heat exchanger. For correct use of such electric drive we solved the problem of control object mathematical model synthesis, which has non-linear properties, in particular, the transfer coefficient of the circuit can vary in more than 6 times. At the same time there was revealed the dependence of the transfer coefficient on the motor speed, which must be considered in the controller synthesis. In conclusion we suggested the solutions of regulators synthesis tasks with customizable settings for speed and switchable structure between relay [lambda] and PI regulators

Moment conditions in strong laws of large numbers for multiple sums and random measures

The validity of the strong law of large numbers for multiple sums $S_n$ of independent identically distributed random variables $Z_k$, $k\leq n$, with $r$-dimensional indices is equivalent to the integrability of $|Z|(\log^+|Z|)^{r-1}$, where $Z$ is the typical summand. We consider the strong law of large numbers for more general normalisations, without assuming that the summands $Z_k$ are identically distributed, and prove a multiple sum generalisation of the Brunk--Prohorov strong law of large numbers. In the case of identical finite moments of irder $2q$ with integer $q\geq1$, we show that the strong law of large numbers holds with the normalisation $\|n_1\cdots n_r\|^{1/2}(\log n_1\cdots\log n_r)^{1/(2q)+\varepsilon}$ for any $\varepsilon>0$. The obtained results are also formulated in the setting of ergodic theorems for random measures, in particular those generated by marked point processes.Comment: 15 page

Atypical antipsychotic therapy in Parkinson's disease psychosis: A retrospective study.

ObjectiveParkinson's disease psychosis (PDP) is a frequent complication of idiopathic Parkinson's disease (iPD) with significant impact on quality of life and association with poorer outcomes. Atypical antipsychotic drugs (APDs) are often used for the treatment of PDP; however, their use is often complicated by adverse drug reactions (ADRs). In this study, we present patients with PDP who were treated with the most commonly used atypical antipsychotic agents and review their respective ADRs.MethodsA retrospective study was carried out to include a total of 45 patients with iPD who visited a movement disorders clinic between 2006 and 2015. All PDP patients treated with atypical APDs were included in the analysis for their specific ADRs.ResultsForty-five iPD patients (mean age of onset: 62.67 ± 9.86 years) were included, of those 10 patients had psychosis (mean age of onset: 76.80 ± 4.61 years). Of the 45 patients, 22.2% were found to have psychotic symptoms, of whom 70% had hallucinations, 20% had delusions, and 10% illusions. Seventy percent of psychotic symptoms occurred after ten or more years from diagnosis of iPD. PDP patients were treated with quetiapine, olanzapine, and risperidone separately or in combination, all of which were found to have certain ADRs.LimitationsThis study was limited by its retrospective study design and small sample size and with likely selection bias.ConclusionsThe prevalence of PDP is relatively high in older patients with iPD. The uses of the currently available atypical APDs in this patient population are often complicated by ADRs. The selective 5-HT 2A inverse agonist, pimavanserin, could be a better alternative in the treatment of PDP

Information Super-Diffusion on Structured Networks

We study diffusion of information packets on several classes of structured networks. Packets diffuse from a randomly chosen node to a specified destination in the network. As local transport rules we consider random diffusion and an improved local search method. Numerical simulations are performed in the regime of stationary workloads away from the jamming transition. We find that graph topology determines the properties of diffusion in a universal way, which is reflected by power-laws in the transit-time and velocity distributions of packets. With the use of multifractal scaling analysis and arguments of non-extensive statistics we find that these power-laws are compatible with super-diffusive traffic for random diffusion and for improved local search. We are able to quantify the role of network topology on overall transport efficiency. Further, we demonstrate the implications of improved transport rules and discuss the importance of matching (global) topology with (local) transport rules for the optimal function of networks. The presented model should be applicable to a wide range of phenomena ranging from Internet traffic to protein transport along the cytoskeleton in biological cells.Comment: 27 pages 7 figure

Kronecker's Double Series and Exact Asymptotic Expansion for Free Models of Statistical Mechanics on Torus

For the free models of statistical mechanics on torus, exact asymptotic expansions of the free energy, the internal energy and the specific heat in the vicinity of the critical point are found. It is shown that there is direct relation between the terms of the expansion and the Kronecker's double series. The latter can be expressed in terms of the elliptic theta-functions in all orders of the asymptotic expansion.Comment: REVTeX, 22 pages, this is expanded version which includes exact asymptotic expansions of the free energy, the internal energy and the specific hea

Electron transport and optical properties of shallow GaAs/InGaAs/GaAs quantum wells with a thin central AlAs barrier

Shallow GaAs/InGaAs/GaAs quantum well structures with and without a three monolayer thick AlAs central barrier have been investigated for different well widths and Si doping levels. The transport parameters are determined by resistivity measurements in the temperature range 4-300 K and magnetotransport in magnetic fields up to 12 T. The (subband) carrier concentrations and mobilities are extracted from the Hall data and Shubnikov-de Haas oscillations. We find that the transport parameters are strongly affected by the insertion of the AlAs central barrier. Photoluminescence spectra, measured at 77 K, show an increase of the transition energies upon insertion of the barrier. The transport and optical data are analyzed with help of self-consistent calculations of the subband structure and envelope wave functions. Insertion of the AlAs central barrier changes the spatial distribution of the electron wave functions and leads to the formation of hybrid states, i.e. states which extend over the InGaAs and the delta-doped layer quantum wells.Comment: 14 pages, pdf fil

Multifractality in Time Series

We apply the concepts of multifractal physics to financial time series in order to characterize the onset of crash for the Standard & Poor's 500 stock index x(t). It is found that within the framework of multifractality, the "analogous" specific heat of the S&P500 discrete price index displays a shoulder to the right of the main peak for low values of time lags. On decreasing T, the presence of the shoulder is a consequence of the peaked, temporal x(t+T)-x(t) fluctuations in this regime. For large time lags (T>80), we have found that C_{q} displays typical features of a classical phase transition at a critical point. An example of such dynamic phase transition in a simple economic model system, based on a mapping with multifractality phenomena in random multiplicative processes, is also presented by applying former results obtained with a continuous probability theory for describing scaling measures.Comment: 22 pages, Revtex, 4 ps figures - To appear J. Phys. A (2000

MUCORMYCOSIS EXPERIENCE OF THE OTORHINOLARYNGOLOGY DEPARTMENT OF THE REPUBLICAN CLINICAL HOSPITAL

Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, Chişinău, Republica MoldovaIntroducere. Mucormicoza reprezintă o infecție fungică invaziva ce afectează preponderent persoanele imunocompromise. Asocierea diabetului zaharat necontrolat si a infecției COVID-19 a avut consecință creșterea numărului de adresări cu mucormicoza în forma rinocerebrala și evoluție severa. Scopul lucrării. Analiza cazurilor de mucormicoza rinocerebrala tratate în clinica ORL a SCR. Material și Metode. Datele anamnestice, clinice și paraclinice au fost prelevate din fișele medicale. Pacienții au fost investigați prin radiografie pulmonară, tomografie computerizată cerebrala și pulmonară, examenul histopatologic a țesuturilor necrotice. A fost studiată literatura privind cazurile similare. Rezultate. În perioada 2020-2022, in clinica ORL s-au adresat 6 cazuri de mucormicoza rinocerebrala clinica tratate combinat: chirurgical și medicamentos. 83.3% au avut în anamnestic infecția COVID-19 in forma grava, cu adresarea în mediu peste 25 de zile de la debutul bolii. 100% din pacienți au fost diagnosticați anterior cu diabet zaharat tip 2 decompensat cu valorile medii ale glicemiei de 18.1mmol/l la adresare. 66% au manifestat complicații oculare, iar 33% au fost diagnosticați cu cecitate. Doar 33% cazuri au fost confirmate histopatologic si au beneficiat de tratament cu amfotericina-B cu vindecare ulterioara, pe când ceilalți au beneficiat de tratament simptomatic, respectiv 16% au avut o evoluție stagnantă, iar 50% au decedat. Concluzii. Mucormicoza dezvoltata pe fundalul imunosupresiei date de infecția COVID-19 si diabet zaharat decompensat necesită tratament chirurgical și medicamentos cu Amfotericina-B administrata precoce, încă de la etapa diagnosticului clinic pentru a reduce numărul deceselor.Background. Mucormycosis is an invasive fungal infection that mainly affects immunocompromised individuals. The combination of uncontrolled diabetes and COVID-19 infection has resulted in an increase in the number of cases of rhinocerebral mucormycosis with severe evolution. Objective of the study. Analysis of cases of rhinocerebral mucormycosis treated in the ENT clinic of SCR. Material and Methods. Anamnestic, clinical and paraclinical data were taken from medical records. Patients were investigated by lung radiography, computed tomography of the brain and lungs, histopathological examination of necrotic tissues. The literature on similar cases has been studied. Results. In the 20202022 period, in the ENT clinic were admitted six cases of clinical rhinocerebral mucormycosis and combination treatment consisting of surgery and drug-therapy was used. 83.3% had a severe COVID-19 infection, with an average of 25 days before the onset of the disease. 100% of patients were previously diagnosed with decompensated type II diabetes with mean blood glucose values of 18.1 mmol/l at admission. 66% had eye complications and 33% were diagnosed with blindness. Only 33% of cases were histopathologically confirmed and received treatment with amphotericin-B with subsequent recovery, while the others received symptomatic treatment, respectively 16% had a stagnant evolution, and 50% died. Conclusion. Mucormycosis developed on the background of immunosuppression caused by COVID-19 infection and decompensated diabetes requires early administered surgical and drug treatment with Amphotericin-B, from the clinical establishment of diagnosis in order to reduce the number of deaths

Decoherence produces coherent states: an explicit proof for harmonic chains

We study the behavior of infinite systems of coupled harmonic oscillators as t->infinity, and generalize the Central Limit Theorem (CLT) to show that their reduced Wigner distributions become Gaussian under quite general conditions. This shows that generalized coherent states tend to be produced naturally. A sufficient condition for this to happen is shown to be that the spectral function is analytic and nonlinear. For a rectangular lattice of coupled oscillators, the nonlinearity requirement means that waves must be dispersive, so that localized wave-packets become suppressed. Virtually all harmonic heat-bath models in the literature satisfy this constraint, and we have good reason to believe that coherent states and their generalizations are not merely a useful analytical tool, but that nature is indeed full of them. Standard proofs of the CLT rely heavily on the fact that probability densities are non-negative. Although the CLT generally fails if the probability densities are allowed to take negative values, we show that a CLT does indeed hold for a special class of such functions. We find that, intriguingly, nature has arranged things so that all Wigner functions belong to this class.Comment: Final published version. 17 pages, Plain TeX, no figures. Online at http://astro.berkeley.edu/~max/gaussians.html (faster from the US), from http://www.mpa-garching.mpg.de/~max/gaussians.html (faster from Europe) or from [email protected]

Force Measurements in Magnetic Suspension and Balance System

The description of an infrared telemetry system for measurement of drag forces in Magnetic Suspension and Balance Systems (MSBS) is presented. This system includes a drag force sensor, electronic pack and transmitter placed in the model which is of special construction, and receiver with a microprocessor-based measuring device, placed outside of the test section. Piezosensitive resonators as sensitive elements and non-magnetic steel as the material for the force sensor are used. The main features of the proposed system for load measurements are discussed and the main characteristics are presented