1,512 research outputs found
Dentro de Redoma de Vidro: o duplo no romance de Sylvia Plath
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Programa de Pós-Graduação em Literatura, Florianópolis, 2010Este trabalho tem por objetivo analisar o "duplo" em A Redoma de Vidro, único romance de Sylvia Plath que foi lançado, inicialmente, sob o pseudônimo de Victoria Lucas, espécie de alter-ego da escritora. Através de elementos da Teoria da Literatura associados à crítica psicanalítica e às estéticas culturais, procurou-se refletir sobre o tema do duplo e seus desdobramentos: alter-ego, dupla personalidade, pseudônimo, narcisismo, imagem e reflexo e alguns elementos místicos como o espelho e a máscara. Dessa forma, o trabalho é dividido em três grandes capítulos: Sylvia Plath - As faces de Lady Lazarus; O estudo sobre o duplo e seus desdobramentos e Por dentro da Redoma de Vidro: o duplo no romance. O desnudar d'A Redoma de Vidro perspassa por um processo simbólico através de um jogo de espelhos que trafega na narrativa, desdobra-se em traços subjetivos e metafóricos tecidos cuidadosamente para formar essa redoma tão bem construída por Sylvia Plath.This dissertation intends to analyze the .double. on .A Redoma de Vidro., Sylvia Plath´s only novel which was published, originally, under the pseudonym of Victoria Lucas, a kind of alter ego of the writer. Through elements of Literature Theory in association with the psychoanalytical critique and cultural aesthetics, the work saught to reflect on the "double" theme and its developments: alter ego, double personality, pseudonym, narcissism, image and reflex and some mythical elements such as the mirror and the mask. In this way the dissertation unveils itself in three major chapters: Sylvia Plath # Lady Lazarus´ faces, The Study on the Double and its Developments and .A Redoma de Vidro. from within: The Double on the Novel. The unveiling of .A Redoma de Vidro. is marked by a symbolic process through a set of mirrors which navigates the narrative, unfolds in subjective and metaphoric traces carefully woven together and form this redome so well constructed by Sylvia Plath
Dynamical membrane curvature instability controlled by intermonolayer friction
International audienceWe study a dynamical curvature instability caused by a local chemical modification of a phospholipid membrane. In our experiments, a basic solution is microinjected close to a giant unilamellar vesicle, which induces a local chemical modification of some lipids in the external monolayer of the membrane. This modification causes a local deformation of the vesicle, which then relaxes. We present a theoretical description of this instability, taking into account both the change of the equilibrium lipid density and the change of the spontaneous membrane curvature induced by the chemical modification. We show that these two types of changes of the membrane properties yield different dynamics. In contrast, it is impossible to distinguish them when studying the equilibrium shape of a vesicle subjected to a global modification. In our model, the longest relaxation timescale is related to the intermonolayer friction, which plays an important part when there is a change in the equilibrium density in one monolayer. We compare our experimental results to the predictions of our model by fitting the measured time evolution of the deformation height to the solution of our dynamical equations. We obtain good agreement between theory and experiments. Our fits enable us to estimate the intermonolayer friction coefficient, yielding values that are consistent with previous measurements
Stick-slip instability for viscous fingering in a gel
The growth dynamics of an air finger injected in a visco-elastic gel (a
PVA/borax aqueous solution) is studied in a linear Hele-Shaw cell. Besides the
standard Saffmann-Taylor instability, we observe - with increasing finger
velocities - the existence of two new regimes: (a) a stick-slip regime for
which the finger tip velocity oscillates between 2 different values, producing
local pinching of the finger at regular intervals, (b) a ``tadpole'' regime
where a fracture-type propagation is observed. A scaling argument is proposed
to interpret the dependence of the stick-slip frequency with the measured
rheological properties of the gel.Comment: 7 pages, 4 figures. Submitted to Europhysics Letter
Collapse of Flux Tubes
The dynamics of an idealized, infinite, MIT-type flux tube is followed in
time as the interior evolves from a pure gluon field to a
plasma. We work in color U(1). pair formation is evaluated
according to the Schwinger mechanism using the results of Brink and Pavel. The
motion of the quarks toward the tube endcaps is calculated by a Boltzmann
equation including collisions. The tube undergoes damped radial oscillations
until the electric field settles down to zero. The electric field stabilizes
the tube against pinch instabilities; when the field vanishes, the tube
disintegrates into mesons. There is only one free parameter in the problem,
namely the initial flux tube radius, to which the results are very sensitive.
Among various quantities calculated is the mean energy of the emitted pions.Comment: 16 pages plus 12 figures. RevTex3. DOE/ER/40427-160N9
Quantum Energies of Interfaces
We present a method for computing the one-loop, renormalized quantum energies
of symmetrical interfaces of arbitrary dimension and codimension using
elementary scattering data. Internal consistency requires finite-energy sum
rules relating phase shifts to bound state energies.Comment: 8 pages, 1 figure, minor changes, Phys. Rev. Lett., in prin
Primary prevention of beta-cell autoimmunity and type 1 diabetes - The Global Platform for the Prevention of Autoimmune Diabetes (GPPAD) perspectives.
OBJECTIVE: Type 1 diabetes can be identified by the presence of beta-cell autoantibodies that often arise in the first few years of life. The purpose of this perspective is to present the case for primary prevention of beta-cell autoimmunity and to provide a study design for its implementation in Europe. METHODS: We examined and summarized recruitment strategies, enrollment rates, and outcomes in published TRIGR, FINDIA and BABYDIET primary prevention trials, and the TEDDY intensive observational study. A proposal for a recruitment and implementation strategy to perform a phase II/III primary prevention randomized controlled trial in infants with genetic risk for developing beta-cell autoimmunity is outlined. RESULTS: Infants with a family history of type 1 diabetes (TRIGR, BABYDIET, TEDDY) and infants younger than age 3 months from the general population (FINDIA, TEDDY) were enrolled into these studies. All studies used HLA genotyping as part of their eligibility criteria. Predicted beta-cell autoimmunity risk in the eligible infants ranged from 3% (FINDIA, TEDDY general population) up to 12% (TRIGR, BABYDIET). Amongst eligible infants, participation was between 38% (TEDDY general population) and 97% (FINDIA). Outcomes, defined as multiple beta-cell autoantibodies, were consistent with predicted risks. We subsequently modeled recruitment into a randomized controlled trial (RCT) that could assess the efficacy of oral insulin treatment as adapted from the Pre-POINT pilot trial. The RCT would recruit infants with and without a first-degree family history of type 1 diabetes and be based on general population genetic risk testing. HLA genotyping and, for the general population, genotyping at additional type 1 diabetes susceptibility SNPs would be used to identify children with around 10% risk of beta-cell autoimmunity. The proposed RCT would have 80% power to detect a 50% reduction in multiple beta-cell autoantibodies by age 4 years at a two-tailed alpha of 0.05, and would randomize around 1160 infants to oral insulin or placebo arms in order to fulfill this. It is estimated that recruitment would require testing of between 400,000 and 500,000 newborns or infants. CONCLUSION: It is timely and feasible to establish a platform for primary prevention trials for type 1 diabetes in Europe. This multi-site European infrastructure would perform RCTs, supply data coordination and biorepository, provide cohorts for mechanistic and observational studies, and increase awareness for autoimmune diabetes.This work was supported by The Leona M. & Harry B. Helmsley Charitable Trust Grants #2015PG-T1D072 and #2015PG-T1D071.This is the final version of the article. It first appeared from Elsevier via http://dx.doi.org/10.1016/j.molmet.2016.02.00
The utility of hypercoordination and secondary bonding for the synthesis of a binary organoelement oxo cluster
A strategy for the preparation of the otherwise difficult to obtain binary organometallic oxides containing two heavy main group elements is described and exemplified by the synthesis of [(p-MeOC6H4)2Te(OSnt-Bu2OH)2]2.<br /
Two-dimensional dilute Bose gas in the normal phase
We consider a two-dimensional dilute Bose gas above its superfluid transition
temperature. We show that the t-matrix approximation corresponds to the leading
set of diagrams in the dilute limit, provided the temperature is sufficiently
larger than the superfluid transition temperature. Within this approximation,
we give an explicit expression for the wave vector and frequency dependence of
the self-energy, and calculate the corrections to the chemical potential and
the effective mass arising from the interaction. We also argue that the
breakdown of the t-matrix approximation, which occurs upon lowering the
temperature, provides a simple criterion to estimate the superfluid critical
temperature for the two-dimensional dilute Bose gas. The critical temperature
identified by this criterion coincides with earlier results obtained by Popov
and by Fisher and Hohenberg using different methods. Extension of this
procedure to the three-dimensional case gives good agreement with recent Monte
Carlo data.Comment: 9 pages, 3 Figure
Local exchange-correlation vector potential with memory in Time-Dependent Density Functional Theory: the generalized hydrodynamics approach
Using Landau Fermi liquid theory we derive a nonlinear non-adiabatic
approximation for the exchange-correlation (xc) vector potential defined by the
xc stress tensor. The stress tensor is a local nonlinear functional of two
basic variables - the displacement vector and the second-rank tensor which
describes the evolution of momentum in a local frame moving with Eulerian
velocity. For irrotational motion and equilibrium initial state the dependence
on the tensor variable reduces to that on a metrics generated by a dynamical
deformation of the system.Comment: RevTex, 5 pages, no figures. Final version published in PR
Static Response Function for Longitudinal and Transverse Excitations in Superfluid Helium
The sum rule formalism is used to evaluate rigorous bounds for the density
and current static response functions in superfluid helium at zero temperature.
Both lower and upper bounds are considered. The bounds are expressed in terms
of ground state properties (density and current correlation funtions) and of
the interatomic potential. The results for the density static response
significantly improve the Feynman approximation and turn out to be close to the
experimental (neutron scattering) data. A quantitative prediction for the
transverse current response is given. The role of one-phonon and multi-particle
excitations in the longitudinal and transverse channels is discussed.
(Phys.Rev.B, in press)Comment: 19 pages (plain TeX) and 3 Figures (postscript), UTF-26
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