415 research outputs found

    Acculturation and oral health status among Tibetan immigrants residing in Bangalore City, India

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    Background: This study is the first of its kind conducted among Tibetans immigrants to Bangalore City, India to study the effects of acculturation on the oral health outcomes of less established group of individuals. Objectives: To determine the Acculturation and oral health status among Tibetan immigrants in Bangalore city and to assess the relationship between them. Materials and Methods: A random sample of 560 immigrants aged 18 years and above from different Tibetan centre of Bangalore city were included for the study. Acculturation was measured using modified Psychological-behavioral acculturation scale. Dental caries experience and periodontal status were recorded. Results: 49.1% of females and 50.9% of males were in highly accultured group. Bivariate analysis using Chi-square test was performed using 5% significance level. Logistic regression analysis demonstrated a strong association between DMFT and Ethnic factors, and periodontal status with language barrier and utilization of health care. Discussion: Reducing disparities in oral health status and in the use of dental services among Tibetan immigrants require attention to cultural factors such as language barrier and age at migration and immigrant’s degree of acculturation

    Glycemic control and its association with medication adherence among type 2 diabetes mellitus patients in Nepal - A hospital based cross-sectional study in Dhulikhel Hospital, Nepal

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    Background Diabetes is a medical condition characterized by high sugar level in blood caused due to impaired insulin production or function. It is steadily increasing everywhere around the world resulting in 1.5 million deaths due to diabetes in 2012 as per WHO report in 2016. The high mortality rate is due to a number of life-threatening health problems caused by uncontrolled glycemia. Medication adherence, among other factors such as diet control, exercise and life-style modification, is one of the necessary pre-conditions to have good glycemic control and therefore, to reduce burden of diabetes. Objectives The primary objectives of this study were (i) to determine the status of glycemic control, (ii) to determine the status of medication adherence for diabetes medicines and (iii) to identify the association between glycemic control and medication adherence. Secondary objectives were to identify the associated factors of medication adherence on diabetes medicines and to identify the association between attendance of diabetes counseling and medication adherence for both formally educated and not formally educated type 2 diabetes mellitus (DM) patients. Methods A hospital based cross sectional study was conducted at laboratory department of Dhulikhel Hospital among the patients visiting for their regular Fasting Blood Sugar (FBS) test from September to December 2016. Inclusion criteria were (i) type 2 DM patients (ii) under diabetes medication from at least past three months (iii) aged ≥18 years. Patients with FBS < 7 mmol/litre and glycated haemoglobin (HbA1c) < 7% were categorized as good glycemic control. The medication adherence was measured with Nepali version of 8 item Morisky Medication Adherence Scale (MMAS-8) (© 2007 Donald E. Morisky). Multivariate linear regression was applied to assess the association of glycemic control (FBS and HbA1c) and medication adherence and multivariate logistic regression to identify the associated factors of medication adherence of diabetes medicines. Both of them were adjusted for sociodemographic and clinical characteristics. Results A total of 343 eligible cases were recruited for the study. Mean age of respondents was 55.8 years, 54.2% were male and 49% belonged to Newar ethnicity. Average FBS was 147.9 (SD: 57.3) mg/dl [8.2 (SD: 3.2) mmol/L] and average HbA1c among 198 participants was 7.8 (SD: 1.8) %. Only 42% had good FBS control while 37.4% had good HbA1c control despite of having high mean MMAS-8 (© 2007 Donald E. Morisky) score of 7.4 (SD: 1) with 60.9% high adherence (score =8), 31.8% moderate adherence (score ≥6 and <8) and 7.3% low adherence (score <6). There was statistically significant association between FBS and medication adherence [β: -14.32 (95% CI: -28.47,-0.16), p=0.047] but no such association between HbA1c and medication adherence. High medication adherence was found to be significantly associated with formal education [AOR: 2.43 (95%CI: 1.34, 4.39), p=0.003] and attendance of diabetes counseling [AOR: 1.76 (95% CI: 1.02, 3.04), p=0.04]. There was no significant interaction between education and attendance of diabetes counseling [95% CI: 0.49, 4.25, p=0.51] in relation to medication adherence. Conclusion The glycemic control among the sample representing Nepalese type 2 DM population was not good though the proportion of high medication adherence was high. There was statistically significant association of glycemia (FBS) with high medication adherence. In addition, high medication adherence was statistically significant with formal education and attendance of diabetes counseling. For all the patients with formal or no formal education, medication adherence had significant association with attendance of diabetes counseling. Hence, we encourage that higher number of type 2 DM patients should take part in counseling program and constant training should be given to health care professionals to conduct diabetes counseling.Denne masteroppgaven vil bli tilgjengelig 29.05.202

    Indian Ocean moisture flux variations during summer monsoon and its relation with Indian rainfall

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    1971-1977In this article, we discussed about the variations of moisture flux (MF) over the Indian Ocean (IO) and successive Indian summer monsoon rainfall (ISMR). MF calculated over 1000-850 mb levels at five different sub regions over the IO during 2006-2014. In monsoons months (June through September), moisture transported from the southern IO through Arabian Sea (AS) via a low-level jet produces rainfall in Indian subcontinent. MF commences in May then increases through August and then decreases by September. We verified the relation of five sub regions MF with ISMR and found northwest IO (NWIO), Arabian Sea (AS) have positive relation. However, the Bay of Bengal (BOB) and the central IO (CIO) indicated negative relation. Strong positive relation observed with correlation coefficients (CC) of 0.81 and 0.72 between MF and ISMR over NWIO and AS respectively, however BOB and CIO reveal an inverse relation (CC of –0.34 and -0.7). During an El Nino year, MF deviations are negative over the NWIO and AS, indicating lower moisture transport to India and consecutive ISMR is low. MF during El Nino/La Nina/normal monsoon season over the NWIO and AS areas are important for ISMR

    Information needs and use of E-resources by the Govt.nursing students in the Digital Environment of Bhubaneswar,Odisha: An analysis

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    Like all other academic areas, nursing education has expanded both vertically and horizontally. There is a substantial body of literature in the chosen topic area, created using both traditional and modern techniques. Additionally, the methods used to produce knowledge in this particular profession have evolved, which has affected how nursing students throughout the world search for information. The current review\u27s objective is to examine several factors related to nursing students\u27 use of electronic resources for information seeking that have been researched by various researchers throughout the world over a range of time periods. The paper discusses a few key elements that are crucial for efficient access to, retrieval of, and transmission of electronic information. The study also analyses how nursing students\u27 information-seeking behaviours have evolved as a result of the altered information environment, particularly in light of the increased use of electronic sources by academia throughout the world with a focus on nursing

    Blood transfusions and its rational use in obstetrics

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    Background: Blood transfusion (BT) during or after delivery is a serious and sometimes a predictable event. This study helps to generate the information and knowledge regarding the various aspects of blood transfusions in obstetrics and its rational use and alternative strategies.Methods: This is retrospective study of 184 obstetric patients who had 288 blood transfusions during the month of March and April 2014 in the department of obstetrics in an urban tertiary care referral government teaching institute.Results: During this study period of 2 months from March to April 2014 there were 907 admissions in the labour room and 642 deliveries. Among these, 184 patients received blood transfusions. Numbers of blood transfused were 288. The main indication of blood transfusion was anaemia.Conclusions: As many as 56% of pregnant women are anaemic depending on the geographic and socio-economic group studies. Various strategies can be implemented to reduce the anaemia and decrease the number of blood transfusions so that patient will receive the maximum benefit with minimal risks

    Maternal mortality at a government teaching hospital: a six year duration study

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    Background: The studies were to help generate information and knowledge regarding the causes of maternal deaths in an urban tertiary health care government hospital and how they can be prevented in a developing country like ours to achieve millennium development goal 5 (MDGS) at reducing the MMR by 75% over the period of 1990-2015.Methods: A retrospective study done in the year of 2014 on 97 maternal deaths over a period of six years from January 2007 to December 2012.Results: During the study period there were 16,534 deliveries, and 97 maternal deaths, giving a maternal mortality rate of 586/100,000 live births. Haemorrhage was leading cause of death. Most women died within 24 hours of admission and most of them were admitted in shock. The majority of the death occurred in the age group 20-30 years and in multigravidas.Conclusions: The maternal mortality rate is much more than the national MMR. Haemorrhage was the leading cause of death followed by septicemia, both of them being preventable by adequate transfusion of blood and its components, delivery in a well-equipped hospital, early identification and prompt action, good antibiotic coverage, and early transportation

    Corrosion Classification, Rate And Corrosion Product Type: A Review

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    Corrosion is a slow process that occurs primarily on metal surfaces, but the corrosion related losses are of high order. When considering only the loss of metal, the damages cannot be measured. Except for the least active noble metals, corrosion occurs with all metals. The indirect losses are much higher. Consideration must also be given to the cost of fabrication and cost of preventing corrosion. Indirect losses are higher than the direct losses. When a structure such as building or bridge collapsed due to problems with corrosion the damage often involves the loss of human life and property and the cost of subsequent reconstruction and alternative solution. Corrosion is quite noticeable in some types of corrosion and is only seen when an accident occurs

    Synergistic Effects of Andrographolide on DNA Damage Repair Mechanism and Apoptosis in Breast Cancer Cells

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    Breast cancer is the second leading cause of cancer deaths in women. Several drugs including cisplatin and carboplatin have shown tremendous effectivity in reducing cancer; however development of drug resistance by breast cancer cells to overcome cytotoxic insults and recurrence of the disease is a major concern at the moment. Andrographolide is a diterpenoid with a potent anti-inflammatory and anti tumor activity and it’s usage in combination therapy would be ideal as it is proven for it’s apoptotic capability in varied number of cells. Antiproliferative and apoptotic activity of andrographolide in triple negative MDA-MB-231 cells was evaluated by clonogenic assay and flow cytometric analysis. Expression and phosphorylation of proteins were evaluated by immunoblotting. Our results revealed dose-dependent cytotoxic effects of andrographolide in MDA-MB-231 cells with and without carboplatin. It resulted in G2/M arrest of cells when treated alone, and further enhanced upon treatment in combination with carboplatin. Andrographolide alone and in combination with carboplatin enhanced apoptotic cells in early, mid and late stages and increased expression of DNA damage repair response proteins including FANCJ, FANCD2, RAD51, pRPA32 and p53. The present study strongly suggests that andrographolide inhibits breast cancer cell proliferation by apoptosis mediated through cell cycle arrest and up regulation of DNA damage repair response gene expression and shows synergistic effects upon usage in combination with carboplatin

    Deblurring of images using blind schemes

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    The thesis presents two blind deconvolution schemes for image blur removal. The two major types of blur has been worked out, namely, the gaussian blur and the motion blur. The image corrupted by the gaussian blur is reconstructed by Evolutionary algorithm using pseudo-wigner distribution. The second method deals with heuristically estimating the blur parameter of the image undergone motion blur. The gaussian effect is mostly observed in astronomical imaging. The image deblurring for motion blurred image is required due to hardware incapability of capturing the exact information of moving object or with moving camera. In this thesis, an observed image is assumed to be the two dimensional convolution of the true image with a linear-shift invariant blur, known as point-spread function, psf, and the additive noise is assumed to be zero. The Evolutionary algorithm has been implemented to remove gaussian blur. The atmospheric turbulence is mostly modelled by the gaussian psf. The algorithm proceeds by randomly generating the psf’s at each generation. The psf’s at each generation are used to estimate the true image. The best fitted images are then given as input to the next generation. After few generation, the most feasible images are chosen. These closer estimated images are fused using pseudo-wigner distribution to reconstruct the final required image. The inherent dynamic characteristic of the nature gives rise to motion blur. Whenever there is relative motion between the object to be captured and the imaging system, the image captured at that instant is suered by the type of blur known as motion blur. A new heuristic approach has been framed out with the purpose of estimating the motion blur parameter. This type of blur is characterised by its length and the motion direction. These parameters are then used to restore the image. The motion direction is estimated from the fourier domain of the observed motion blurred image. The length is then iteratively computed using Entropy and the RMSE as the quality metrics
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