Prognostic role of minimal residual disease before and after hematopoietic stem cell transplantation in childhood acute lymphoblastic leukemia

More than 80% of children with acute lymphoblastic leukemia (ALL) can be cured through intensive and risk-oriented chemotherapy protocols. Allogeneic hematopoietic stem cell transplantation (HSCT) is considered bene\ufb01cial for approximately 10% of the patients who are at veryhigh risk at frontline therapy and for the majority of patients after relapse. Consequently, it is critically important to identify prognostic factors in this group of patients in order to tailor risk-adapted therapy. In this retrospective study, we aimed to assess the prognostic role of minimal residual disease (MRD) before HSCT and at di\ufb00erent time points after transplantation in children with ALL

Voice and movement in circle with body percussion. Facilitation in learning observed in voice BAPNE® method and in circlesongs teaching

The proposal of this study reported here by Elisa Pezzuto, currently post graduate student in ethnomusicology, and by Alberto Quarello, teacher and manager of the vocal department of the voice BAPNE® method inside of BAPNE® method, is about music education; this study highlights how the use of a choral activity called circlesinging can help giving, in a really short time, the comprehension of many technical factors both in vocal and musical field increasing at the same time the rapidity in learning and enhancing the attention level using specific exercises to stimulate the development of multiple intelligence on the basis of Howard Gardner theory. The scientific basis in wich this argument has been observed is provided by the direct experience of Alberto Quarello, who led many workshops about this since 2006 until now meeting and working with more than five thousand people with deeply different backgrounds. Because this study is essentially about choral didactics, it is also fundamental the contribution of the musicological and ethnomusicological research about the analysis on the development of musical intelligence

The Unpublished Working Drawings for the Nineteenth-Century Restoration of the Double Structure of the Real Chiesa di San Lorenzo in Torino

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