MI RISK ASSESSMENT IN PATIENS USING EZ-CVD RISK ASESSMENT TOOL

BACKGROUND: MI is one of the leading causes of the mortality. Early detection of MI Risk prevents morbidity and mortality. Aim of this study is to assess the future risk of MI in individuals with risk factors and prevent further complications by using EZ-CVD risk assessment tool. OBJECTIVE:  To assess the risk of MI among individuals in the productive age group using EZ-CVD risk assessment tool. METHOD: This is a prospective observational and interventional study conducted over a period of 6 months after obtaining the institutional human ethics committee approval. EZ-CVD risk assessment tool was used in this study which includes 6 self-reporting questionaries’ such as age, gender, history of diabetes, history of smoking, history of hypertention, family history of heart attack at the age of 60 or younger. A score of 6 or greater is considered as patients are at high risk of having MI. RESULTS: Sixty subjects were enrolled in to this study using the inclusion criteria. Among them, 36 were males and 24 individuals were females. Out of sixty recruited, 23 found having high risk for MI attack and 37 were at low risk of having chances of further MI. CONCLUSION: The study concludes that EZ-CVD risk assessment tool was found useful to predict the occurrence of future MI

Exploring the Bioactive Components of Stevia Essential Oil and Their Versatile Applications in the Food, Cosmetic, and Agricultural Domains

The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link. Review paper, contributions from: Department of Chemistry, Baba Farid College, Bathinda, Punjab, India Department of Biotechnology, Baba Farid College, Bathinda, Punjab, India Department of Paramedical Sciences, Baba Farid College of Engineering and Technology, Bathinda, Punjab, India Department of Pharmacy, Biological and Health Sciences Center, Federal University of Maranhão, São Luís, Maranhão, Brazil Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, United KingdomEssential oils have become popularized in various sectors due to their numerous beneficial effects. The global prominence of essential oils is attributed to the synergistic impact of their bioactive constituents. To meet the ever rising demand, industries are looking for the new renewable and natural sources of essential oils or their components. Stevia, primarily known as a natural- sweetener, also contains essential oils that possess various biological properties. Different parts of Stevia plant possess essential oils and their components vary depending on the extraction method and physical or geographical conditions. The volatile oil obtained fromStevia contains several active components including aromatics, aldehydes, monoterpenes, and sesquiterpenes with antioxidant and antimicrobial activities, which are important in food preservation. The constituents of Stevia essential oil hold promising potential for application in the agricultural sector as anti-plasmodia, aphicidal, and insecticidal agents. In addition, their anti-inflammatory, antiaging, and skin-brightening effects make them valuable for use in cosmetic formulations. Evaluating the safety assessment of various components of Stevia essential oil is critical to support its potential use in various industries, highlighting its broad spectrum of applications

In(OTf)₃ assisted synthesis of β-carboline C-3 tethered imidazo[1,2-a]azine derivatives

Synthesis of β-carboline based natural products and synthetic derivatives is one of the frontier areas of research owing to their medicinal properties.</p

Epidemiological Determinants of Acute Respiratory Syndrome Coronavirus-2 Disease Pandemic and The Role of the Bacille-Calmette-Guerin Vaccine in Reducing Morbidity and Mortality

This study analyzed the determinants of morbidity, mortality, and case fatality rate (CFR) of the ongoing pandemic of severe acute respiratory syndrome coronavirus-2 disease 2019 (COVID-19). Data for 210 countries and territories available in public domains were analyzed in relation to mandatory vaccination with Bacille-Calmette-Guerin (BCG), population density, median age of the country population, health care expenditure per capita, life expectancy at birth, healthy life expectancy, literacy rate, per capita gross domestic production adjusted to purchasing power (PPP), burden of tuberculosis (TB), acquired immunodeficiency disease caused by human immunodeficiency virus (HIV-AIDS), malaria, cardiovascular disease (CVD), neoplasm, diabetes, deaths due to energy-protein (food) deficiency (EPD), and per capita government spending on safe water and sanitation. Mandatory BCG vaccination showed a highly significant (p<0.0001) negative correlation with COVID-19 morbidity (r = -0.62) and mortality (r = -0.58) rates, but no significant correlation with CFR. The median age of the nation showed a significant (p<0.0001) positive correlation with COVID-19 morbidity (r= 0.40) and mortality (r = 0.34) rates, but no significant correlation with CFR. The pandemic resulted in higher morbidity (r= 0.47, p<0.0001) and mortality (r= 0.25, p = 0.01) rates in countries with a higher PPP than in those with a lower PPP. COVID-19 CFR and morbidity and mortality rates showed no significant correlation with population density, the burden of malaria or diabetes, or the level of spending on safe water and sanitation. Only the burden of TB showed a positive correlation with CFR (r = 0.17, p = 0.05). However, COVID-19 morbidity showed a significant (p ≤0.05) negative correlation with the burden of TB, HIV-AIDS, CVD, and EPD. Mortality and morbidity in COVID-19 patients showed a positive correlation with per capita health expenditure, life expectancy, the burden of neoplasia, and PPP

Epidemiological Determinants of Acute Respiratory Syndrome Coronavirus-2 Disease Pandemic and The Role of the Bacille-Calmette-Guerin Vaccine in Reducing Morbidity and Mortality

This study analyzed the determinants of morbidity, mortality, and case fatality rate (CFR) of the ongoing pandemic of severe acute respiratory syndrome coronavirus-2 disease 2019 (COVID-19). Data for 210 countries and territories available in public domains were analyzed in relation to mandatory vaccination with Bacille-Calmette-Guerin (BCG), population density, median age of the country population, health care expenditure per capita, life expectancy at birth, healthy life expectancy, literacy rate, per capita gross domestic production adjusted to purchasing power (PPP), burden of tuberculosis (TB), acquired immunodeficiency disease caused by human immunodeficiency virus (HIV-AIDS), malaria, cardiovascular disease (CVD), neoplasm, diabetes, deaths due to energy-protein (food) deficiency (EPD), and per capita government spending on safe water and sanitation. Mandatory BCG vaccination showed a highly significant (p&lt;0.0001) negative correlation with COVID-19 morbidity (r = -0.62) and mortality (r = -0.58) rates, but no significant correlation with CFR. The median age of the nation showed a significant (p&lt;0.0001) positive correlation with COVID-19 morbidity (r= 0.40) and mortality (r = 0.34) rates, but no significant correlation with CFR. The pandemic resulted in higher morbidity (r= 0.47, p&lt;0.0001) and mortality (r= 0.25, p = 0.01) rates in countries with a higher PPP than in those with a lower PPP. COVID-19 CFR and morbidity and mortality rates showed no significant correlation with population density, the burden of malaria or diabetes, or the level of spending on safe water and sanitation. Only the burden of TB showed a positive correlation with CFR (r = 0.17, p = 0.05). However, COVID-19 morbidity showed a significant (p ≤0.05) negative correlation with the burden of TB, HIV-AIDS, CVD, and EPD. Mortality and morbidity in COVID-19 patients showed a positive correlation with per capita health expenditure, life expectancy, the burden of neoplasia, and PPP.</jats:p