2,090 research outputs found

    The management of de-cumulation risks in a defined contribution environment

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    The aim of the paper is to lay the theoretical foundations for the construction of a flexible tool that can be used by pensioners to find optimal investment and consumption choices in the distribution phase of a defined contribution pension scheme. The investment/consumption plan is adopted until the time of compulsory annuitization, taking into account the possibility of earlier death. The effect of the bequest motive and the desire to buy a higher annuity than the one purchasable at retirement are included in the objective function. The mathematical tools provided by dynamic programming techniques are applied to find closed form solutions: numer-ical examples are also presented. In the model, the trade-off between the different desires of the individual regarding consumption and final annuity can be dealt with by choosing appropriate weights for these factors in the setting of the problem. Conclusions are twofold. Firstly, we find that there is a natural time-varying target for the size of the fund, which acts as a sort of safety level for the needs of the pensioner. Secondly, the personal preferences of the pensioner can be translated into optimal choices, which in turn affect the distribution of the consumption path and of the final annuity

    Measures of Niche Overlap, I

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    Many methods of measuring niche overlap have been proposed, such as those of Renkonen, Morisita, and Horn. In this paper, conditions are put forward which overlap indices should reasonably be expected to satisfy. A general description of a good index is given, which covers as special cases those of the well-known indices which satisfy all the conditions. A mixture of the Renkonen and van Belle & Ahmad indices is suggested, as it has many desirable properties. The problem of estimating overlap from data is discussed briefl

    Measures of Niche Overlap, II

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    An axiomatic basis for the construction of measures of niche overlap is analysed, and its implications are discussed, with particular reference to the more commonly used measures. A method of establishing that a measure of overlap complies with the axioms is put forward, making possible the construction of families of new measures. Certain extremal measures of overlap are also identifie

    Identification of Photorhabdus asymbiotica in cases of human infection

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    Two complete syntheses of (S)-aspartate semi-aldehyde and demonstration that Delta(2)-tetrahydroisophthalic acid is a non-competitive inhibitor of dihydrodipicolinate synthase

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    The document attached has been archived with permission from the publisher.We report, in full, two 3-step syntheses of (S)-aspartate semi-aldehyde, an important synthetic and biosynthetic precursor, from diprotected aspartic acid. The first synthesis proceeds via a thioester, the second via a Weinreb amide. Each route yields pure (S)-aspartate semi-aldehyde in excellent yield. The utility of (S)-aspartate semi-aldehyde prepared in this manner was demonstrated with an inhibition study of dihydrodipicolinate synthase, wherein Δ2- tetrahydroisophthalic acid is shown to be a non-competitive inhibitor with respect to both substrates.Sarah J. Roberts, Jonathan C. Morris, Renwick C.J. Dobson, Chris L. Baxter, and Juliet A. Gerrar

    Simulations of a lattice model of two-headed linear amphiphiles: influence of amphiphile asymmetry

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    Using a 2D lattice model, we conduct Monte Carlo simulations of micellar aggregation of linear-chain amphiphiles having two solvophilic head groups. In the context of this simple model, we quantify how the amphiphile architecture influences the critical micelle concentration (CMC), with a particular focus on the role of the asymmetry of the amphiphile structure. Accordingly, we study all possible arrangements of the head groups along amphiphile chains of fixed length N=12N=12 and 16 molecular units. This set of idealized amphiphile architectures approximates many cases of symmetric and asymmetric gemini surfactants, double-headed surfactants and boloform surfactants. Consistent with earlier results, we find that the number of spacer units ss separating the heads has a significant influence on the CMC, with the CMC increasing with ss for s<N/2s<N/2. In comparison, the influence of the asymmetry of the chain architecture on the CMC is much weaker, as is also found experimentally.Comment: 30 pages, 17 fgure
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