Honesty mediates the relationship between serotonin and reaction to unfairness

How does one deal with unfair behaviors? This subject has long been investigated by various disciplines including philosophy, psychology, economics, and biology. However, our reactions to unfairness differ from one individual to another. Experimental economics studies using the ultimatum game (UG), in which players must decide whether to accept or reject fair or unfair offers, have also shown that there are substantial individual differences in reaction to unfairness. However, little is known about psychological as well as neurobiological mechanisms of this observation. We combined a molecular imaging technique, an economics game, and a personality inventory to elucidate the neurobiological mechanism of heterogeneous reactions to unfairness. Contrary to the common belief that aggressive personalities (impulsivity or hostility) are related to the high rejection rate of unfair offers in UG, we found that individuals with apparently peaceful personalities (straightforwardness and trust) rejected more often and were engaged in personally costly forms of retaliation. Furthermore, individuals with a low level of serotonin transporters in the dorsal raphe nucleus (DRN) are honest and trustful, and thus cannot tolerate unfairness, being candid in expressing their frustrations. In other words, higher central serotonin transmission might allow us to behave adroitly and opportunistically, being good at playing games while pursuing self-interest. We provide unique neurobiological evidence to account for individual differences of reaction to unfairness

Direct thrust measurement of a permanent magnet helicon double layer thruster

Direct thrust measurements of a permanent magnet helicon double layer thruster have been made using a pendulum thrust balance and a high sensitivity laser displacement sensor. At the low pressures used (0.08 Pa) an ion beam is detected downstream of the thruster exit, and a maximum thrust force of about 3 mN is measured for argon with an rf input power of about 700 W. The measured thrust is proportional to the upstream plasma density and is in good agreement with the theoretical thrust based on the maximum upstream electron pressure

COMPARISON OF SINGLE- AND MULTILAYER MATERIALS USED AS DAMPENING ELEMENTS IN KNEE-PROTECTORS

The purpose of this study was to identify characteristics of protectors and materials used to assemble protectors, which can be used to create a ranking and proof that a protector has the effects wanted. Single layer neoprene of increasing material strength (n=7) was compared to prototype multilayer materials (n=18) and different commercially available knee protectors (n=18). The test object was attached to a realistic knee dummy, and a fall to the floor was recorded, both kinematically and kinetically. Maximum acceleration and pressure on a single sensor was calculated at the time of the impact, as well as the height of the first rebounce after impact. For single layer materials, results showed a linear correlation of material strength and all three measured parameters. While max. acceleration and pressure both decreased with growing material strength, bounce height increased. This behaviour cannot be observed in multilayer systems. For our test materials as well as fully assembled protectors, pressure values were almost identical, while bounce height varied in a wide range. Different protectors showed great difference in their effectiveness to reduce maximum acceleration

Easing the survey burden: Quantitative assessment of low-cost signal surveys for indoor positioning

© 2016 IEEE. Indoor positioning through signal fingerprinting is a popular choice since it requires little or no additional infrastructure. However, the initial creation and subsequent maintenance of the signal maps remains a challenge since traditional manual surveying is not scalable. In this work we look at the use of path surveys, which attempt to construct the signal maps from a sparse set of fingerprints collected while a person walks through a space. As such, the survey points rarely provide a uniform coverage of the space of interest. We quantitatively evaluate path surveys with reference to a detailed manual survey using smartphone-grade equipment. We compare both the individual maps (generated using Gaussian Process regression) and their collective positioning performance. Our results are for both WiFi and Bluetooth Low Energy signals. We show that a path survey can provide maps of equivalent quality to a manual survey if a series of guidelines we provide are followed

Projected sea level rise and changes in extreme storm surge and wave events during the 21st century in the region of Singapore

Singapore is an island state with considerable population, industries, commerce and transport located in coastal areas at elevations less than 2 m making it vulnerable to sea-level rise. Mitigation against future inundation events requires a quantitative assessment of risk. To address this need, regional projections of changes in (i) long-term mean sea level and (ii) the frequency of extreme storm surge and wave events have been combined to explore potential changes to coastal flood risk over the 21st century. Local changes in time mean sea level were evaluated using the process-based climate model data and methods presented in the IPCC AR5. Regional surge and wave solutions extending from 1980 to 2100 were generated using ~ 12 km resolution surge (Nucleus for European Modelling of the Ocean – NEMO) and wave (WaveWatchIII) models. Ocean simulations were forced by output from a selection of four downscaled (~ 12 km resolution) atmospheric models, forced at the lateral boundaries by global climate model simulations generated for the IPCC AR5. Long-term trends in skew surge and significant wave height were then assessed using a generalised extreme value model, fit to the largest modelled events each year. An additional atmospheric solution downscaled from the ERA-Interim global reanalysis was used to force historical ocean model simulations extending from 1980–2010, enabling a quantitative assessment of model skill. Simulated historical sea surface height and significant wave height time series were compared to tide gauge data and satellite altimetry data respectively. Central estimates of the long-term mean sea level rise at Singapore by 2100 were projected to be 0.52 m (0.74 m) under the RCP 4.5 (8.5) scenarios respectively. Trends in surge and significant wave height 2 year return levels were found to be statistically insignificant and/or physically very small under the more severe RCP8.5 scenario. We conclude that changes to long-term mean sea level constitute the dominant signal of change to the projected inundation risk for Singapore during the 21st century. We note that the largest recorded surge residual in the Singapore Strait of ~ 84 cm lies between the central and upper estimates of sea level rise by 2100, highlighting the vulnerability of the region

Investigation of the reactivity of AlCl3 and CoCl2 toward molten alkali-metal nitrates in order to synthesize CoAl2O4

Cobalt aluminate CoAl2O4 powder, constituted of nano-sized crystallites, is prepared, involving the reactivity of AlCl3 and CoCl2 with molten alkali-metal nitrates. The reaction at 450 °C for 2 h leads to a mixture of spinel oxide Co3O4 and amorphous γ-Al2O3. It is transformed into the spinel oxide CoAl2O4 by heating at 1000 °C. The powders are mainly characterized by XRD, FTIR, ICP, electron microscopy and diffraction, X-EDS and diffuse reflection. Their properties are compared to those of powders obtained by solid state reactions of a mechanical mixture of chlorides or oxides submitted to the same thermal treatment

Comparative effectiveness of dual-action versus single-action antidepressants for the treatment of depression in people living with HIV/AIDS

Background Depression is the most common psychiatric comorbidity among people living with HIV/AIDS (PLWHA). Little is known about the comparative effectiveness between different types of antidepressants used to treat depression in this population. We compared the effectiveness of dual-action and single-action antidepressants in PLWHA for achieving remission from depression. Methods We used data from the Centers for AIDS Research Network of Integrated Clinic Systems to identify 1175 new user dual-action or single-action antidepressant treatment episodes occurring from 2005 to 2014 for PLWHA diagnosed with depression. The primary outcome was remission from depression defined as a Patient Health Questionnaire-9 (PHQ-9) score <5. Mean difference in PHQ-9 depressive symptom severity was a secondary outcome. The main approach was an intent-to-treat (ITT) evaluation complemented with a per protocol (PP) sensitivity analysis. Generalized linear models were fitted to estimate treatment effects. Results In ITT analysis, 32% of the episodes ended in remission for both dual-action and single-action antidepressants. The odds ratio (OR) of remission was 1.02 (95%CI=0.63,1.67). In PP analysis, 40% of dual-action episodes ended in remission compared to 32% in single-action episodes. Dual-action episodes had 1.33 times the odds of remission (95%CI=0.55,3.21), however the result was not statistically significant. Non-significant differences were also observed for depressive symptom severity. Limitations Missing data was common but was addressed with inverse probability weights. Conclusions Results suggest that single-action and dual-action antidepressants are equally effective in PLWHA. Remission was uncommon highlighting the need to identify health service delivery strategies that aid HIV providers in achieving full remission of their patients’ depression

Bellrock: Anonymous Proximity Beacons from Personal Devices

Proximity beacons provide simple, low-cost location data. However, beacon deployments remain rare. In this paper we introduce Bellrock, a framework that repurposes static personal devices (phones, laptops, etc.) as proximity beacons without revealing the location of the device owners, and provides conventional beacons with access control. This is done by using mutable pseudo-anonymous identifiers that can be unmasked by a cloud service. We develop Bellrock as a general framework, describing the repurposing scheme and the anonymisation techniques, before applying it to Bluetooth Low Energy beacons. We implement and demonstrate the scalability of the de-anonymisation server, which uses a series of heuristics. We implement a Bellrock client on Android and demonstrate negligible impact on battery lifetime. We evaluate Bellrock using extensive real-world office worker movements. We find that Bellrock was able to provide proximity locations for 8,542 of the 21,796 failed locations that would have occurred without it. We further find that office workers were in range of one or more of their co-workers over 90\% of the time, indicating Bellrock can provide relative proximity information even in the absence of a conventional beacon deployment. Overall, we find that Bellrock is both feasible and practical, providing a beacon deployment where there was none, or supplementing existing deployments

Using Bibliometric Big Data to Analyze Faculty Research Productivity in Health Policy and Management

Bibliometric big data and social media tools provide new opportunities to aggregate and analyze researchers' scholarly impact. The purpose of the current paper is to describe the process and results we obtained after aggregating a list of public Google Scholar profiles representing researchers in Health Policy and Management or closely-related disciplines. We extracted publication and citation data on 191 researchers affiliated with health administration programs in the U.S. With these data, we created a publicly available listing of faculty that includes each person's name, affiliation, year of first citation, total citations, h-index, and i-10 index. The median of total citations per individual faculty member was 700, while the maximum was 46,363. The median h-index was 13, while the maximum was 91. We plan to update these statistics and add new faculty to our public listing as new Google Scholar profiles are created by faculty members in the field. This listing provides a resource for students and faculty in our discipline to easily compare productivity and publication records of faculty members in their own and other departments. Similarly, this listing provides a resource for faculty, including department chairs and deans, who desire discipline-specific context for promotion and tenure processes