Sleep and inflammation in resilient aging.

Sleep quality is important to health, and increasingly viewed as critical in promoting successful, resilient aging. In this review, the interplay between sleep and mental and physical health is considered with a focus on the role of inflammation as a biological pathway that translates the effects of sleep on risk of depression, pain and chronic disease risk in aging. Given that sleep regulates inflammatory biologic mechanisms with effects on mental and physical health outcomes, the potential of interventions that target sleep to reduce inflammation and promote health in aging is also discussed

Angular correlations between LBQS and APM: Weak Lensing by the Large Scale Structure

We detect a positive angular correlation between bright, high-redshift QSOs and foreground galaxies. The QSOs are taken from the optically selected LBQS Catalogue, while the galaxies are from the APM Survey. The correlation amplitude is about a few percent on angular scales of over a degree. It is a function of QSO redshift and apparent magnitude, in a way expected from weak lensing, and inconsistent with QSO-galaxy correlations being caused by physical associations, or uneven obscuration by Galactic dust. The correlations are ascribed to the weak lensing effect of the foreground dark matter, which is traced by the APM galaxies. The amplitude of the effect found here is compared to the analytical predictions from the literature, and to the predictions of a phenomenological model, which is based on the observed counts-in-cells distribution of APM galaxies. While the latter agree reasonably well with the analytical predictions (namely those of Dolag & Bartelmann 1997, and Sanz et al. 1997), both under-predict the observed correlation amplitude on degree angular scales. We consider the possible ways to reconcile these observations with theory, and discuss the implications these observations have on some aspects of extragalactic astronomy.Comment: 9 pages; MNRAS, in pres

Mindfulness meditation and improvement in depressive symptoms among Spanish- and English speaking adults: A randomized, controlled, comparative efficacy trial.

ObjectiveLatino immigrants experience acculturative stress and increased depression risk. Mindfulness meditation improves depressive symptoms, yet the vast majority of research has focused on English speaking populations.MethodsIn this randomized clinical trial with 2 parallel treatment groups, adults with moderate levels of perceived stress (n = 76) were recruited from the Los Angeles community from October 2015 to March 2016, stratified into Spanish- (n = 36) and English speaking (n = 40) language groups, and randomized for 6 weeks of treatment with standardized mindful awareness practices (MAPs) or health education (HE). Main outcome measure was depressive symptoms, measured by the Beck Depression Inventory.ResultsUsing an intent-to-treat analysis, the primary outcome, depressive symptoms as indexed by the Beck Depression Inventory, showed greater improvement in MAPs vs. HE, with a between-group post-intervention mean difference of -2.2 (95% CI -4.4 - -0.07) and effect size of 0.28; similar effect sizes were found in the the Spanish- (0.29) and English speaking (0.30) groups. MAPs showed significant improvement relative to HE on secondary outcome of mindfulness with between group difference of 10.7 (95% CI4.5-16.9), but not perceived stress.ConclusionThe comparable efficacy of Spanish and English formats of mindfulness meditation in improving depressive symptoms suggests that this community based intervention may mitigate depression risk in Latino adults who are experiencing social adversity.Trial registrationClinicalTrials.gov NCT03545074

THE EFFECTS OF FUTURES TRADING BY LARGE HEDGE FUNDS AND CTAS ON MARKET VOLATILITY

This study uses the newly available data from the CFTC to investigate the market impact of futures trading by large hedge funds and CTAs. Regression results show that there is a positive relationship between the trading volume of large hedge funds and CTAs and market volatility. However, a positive relationship between hedge fund and CTA trading volume and market volatility is consistent with either a private information or noise trader hypothesis. Three additional tests are conducted to distinguish between the private information hypothesis and the noise trader hypothesis. The first test consisted of identifying the noise component exhibited in return variances over different holding periods. The variance ratio tests provide little support for the noise trader hypothesis. The second test examined whether positive feedback trading characterized large hedge fund and CTA trading behavior. These results suggest that trading decisions by large hedge funds and CTAs, although influenced in small part by past price changes, are not driven by past price changes. The third test consists of estimating the profits and losses associated with the open interest positions of large hedge funds and CTAs. This test is based on the argument that speculative trading can only be destabilizing if speculators buy when prices are high and sell when prices are low, which in turn, implies that destabilizing speculators lose money. Across all thirteen markets, the profit for large hedge funds and CTAs is estimated to be just under $400 million. This implies that the trading decisions are likely based on valuable private information. Overall, the evidence presented in this study suggests trading by large hedge funds and CTAs is based on private fundamental information. These findings imply large hedge funds and CTAs benefit market efficiency by bringing valuable, fundamental information to the market through their trading.hedge fund, commodity trading advisor, volatility, market efficiency, futures markets, Marketing,

A numerical approach to controller design for the ACES facility

In recent years the employment of active control techniques for improving the performance of systems involving highly flexible structures has become a topic of considerable research interest. Most of these systems are quite complicated, using multiple actuators and sensors, and possessing high order models. The majority of analytical controller synthesis procedures capable of handling multivariable systems in a systematic way require considerable insight into the underlying mathematical theory to achieve a successful design. This insight is needed in selecting the proper weighting matrices or weighting functions to cast what is naturally a multiple constraint satisfaction problem into an unconstrained optimization problem. Although designers possessing considerable experience with these techniques have a feel for the proper choice of weights, others may spend a significant amount of time attempting to find an acceptable solution. Another disadvantage of such procedures is that the resulting controller has an order greater than or equal to that of the model used for the design. Of course, the order of these controllers can often be reduced, but again this requires a good understanding of the theory involved

Generic advertising impacts on demands for orange juice in fifty Nielsen metropolitan regions

Agribusiness, Demand and Price Analysis,

Earthsongs: ecopoetics, Heidegger and dwelling

This paper discusses the notion of ecopoetics in relation to the work of Martin Heidegger and his concept of dwelling. Our aim, broadly stated, is to respond to the question: "What frame of mind could bring about sustainability - and how might we develop it?" In the first part of the paper, we comment on Jonathan Bate's notion of ecopoetics and his discussion of Heidegger. Crucial here is the question of whether we can ever approach Nature in an non-ideological way or are all attempts to capture Nature, theoretically or poetically or narratively, nothing more than our own peculiar appropriation of it? Ecopoetics might be conceived as a response to this question, although we dispute Bate's view. In the second part of the paper, following Micheal Haar's perceptive reading, we elaborate the four senses that Heidegger gives to Nature, and in the third section, we make some concluding comments about the notion of sustainability that might be explicated in relation to Heidegger's four senses of Nature