Work from home:Benefits and Pitfalls among software employees

Introduction: Work from home is referred to as employees need not go to corporate companies, but instead perform their work at home using an internet connection, by satellite connection. The employees are happier working from home than in the office. Benefits of working from home is the employees can spend time with family, releasing travelling stress. Therefore, the aim of this study is to find work from home : benefits and pitfalls among the software employees Materials and methods: In this study sample size was 100 software employees between the age group of 20-50 years from software companies in Chennai, Tamil Nadu, India. The questionnaire comprising 21 questions were created in google forms and sent to 100 software employees through whats app. And the data is collected and analysed by spss version 23. Descriptive statistics was expressed by means of number and frequency and percentage and the chi square test was used to find out associated between variables. Levels of statistical significance will be P<0.05 Results: Out of the total 101 responses, 67% were males and 33% were females. 40.59% males said yes that their home is office silent and 26.73% said no. And females said 11.88% said yes that their home is office silent and 20.79%said no. 17.82% female said work from home time saving 2.97% said it is stressful. 0.99% males said time saving and 3.96% said stressful Conclusion: Based on the results of the present study, it can be concluded that work from home is found to be beneficial among the study participants

Knowledge, Awareness, And Practice of Complementary and Alternative Medicine for Oral Health Care Management Among Dental Students

Introduction: Oral health is a contemplation of social, psychological, and physiological factors which are important for our quality of life. CAM represents the group of various medical and health care practices, systems, and products which are not regarded to be a part of conventional medicine. It is considered to be a cheaper and much less side effect. Hence the aim of the study is to assess the knowledge, awareness, and practice of Complementary and Alternative medicine for oral health care management among dental students. Materials and method: Data collection was done by questionnaire survey.Study population contains 100 interns and postgraduates from four different dental colleges. Data was entered in Microsoft excel sheet after collection and was analysed using SPSS software. Descriptive statistics were expressed by means of number, frequency, and percentage. Chi-square test was used to find the association between year of study and Number of responses provided by the participants. Results: The present study reported that 30% of interns and 24% of postgraduates had knowledge regarding oriental medicine/CAM. 30% of interns and 19% of postgraduates knew that hypnosis dentistry can be used to treat anxious patients. 35% interns and 30% postgraduates knew acupuncture can be used as anesthetic and analgesic. Conclusion: Based on the results of the present study it can be concluded that there was more awareness among interns than post graduates, many studies conducted showed some similar and some opposing results to the present study

PROMINENT BACTERIAL ISOLATES FOR DECOLOURISATION OF DISTILLERY SPENT WASH

Molasses-based distilleries produce large volumes of spent wash, a major environmental pollutant due to its high organic load and dark brown color. This coloration is primarily caused by melanoidins, which form through the Maillard reaction, a non-enzymatic process between sugars and amino acids. In this study, eight promising bacterial strains were selected from 40 isolates and designated as S1, S2, S3, S4, S5, S6, S7, and S8. These isolates were screened for their ability to decolorize distillery spent wash using both qualitative and quantitative analyses. Among them, isolate S5 exhibited the highest decolorization potential across different spent wash concentrations (10%, 20%, and 40%). Notably, at a 10% concentration, isolate S5 achieved complete (100%) decolorization, making it the most efficient strain in this study. Based on preliminary characterization, isolate S5 was tentatively identified as Planococcus species. Its exceptional decolorization ability suggests that it holds significant potential for commercial application in the bioremediation of distillery wastewater. Further research on optimizing environmental conditions and scaling up the process could pave the way for an eco-friendly and cost-effective solution to mitigate the environmental impact of distillery effluents

Isolation of genomic DNA from acetone-dried Aspergillus mycelia

A simple acetone-drying protocol was adopted to replace the lyophilization step while isolating genomic DNA from Aspergillus mycelia. This DNA is suitable for PCR, restriction enzyme digestion and Southern blot analysis with digoxigenin-labeled DNA probes. Acetone drying/ preservation can be a useful method in the molecular analysis of fungal DNA samples

FACTS Controllers for Grid Connected Wind Energy Conversion Systems

In this paper, the dynamic performance of grid connected wind energy conversion system (WECS

GO NATURAL, SAY NO TO CHEMICALS - A SYSTEMATIC REVIEW ON EFFECTIVENESS OF GREEN TEA EXTRACT CONTAINING FORMULATIONS ON DENTAL CARIES

Objective: In recent years, the side effects encountered with the use of chemicals has led to the search for safe anticariogenic alternatives. Green tea is one such naturally occurring alternative which possesses anticariogenic activity through a direct bactericidal effect against cariogenic microorganisms. Therefore, the objective of this systematic review was to analyze the existing literature on the effectiveness of green tea extract containing formulations on dental caries. Methods: The databases of PubMed, Cochrane, Science Direct, Metapress, and Google Scholar were searched up to July 2015 for the related topic. References of the selected articles and relevant reviews were searched for any missed publications. Results: The systematic search revealed a total of 437 publications which were scrutinized based on eligibility criteria. Six publications fulfilled the criteria and 431 publications were excluded from the review. Out of six studies, three studies reported a statistically significant difference in favor of green tea while two studies showed no statistically significant difference between the groups. One study reported no statistically significant difference between the two groups; however, the reduction observed in chlorhexidine (control group) was slightly greater than green tea. Conclusion: With the available evidence, it can be concluded that green tea extract containing formulations are effective in reducing cariogenic microflora and caries increment

Splenic Hydatid Cyst- A Case Report

Asymptomatic hydatid cyst presents as an incidental finding. It is caused by Echinococcus granulosus. The liver is known to be involved organ, while the spleen is rarely involved. Hydatid cyst of the spleen should be considered as one of the differential diagnosis in patients presenting with left hypochondriac pain.This poses a clinical challenge. The decision on conservation or surgery is also a dilemma. To decrease incidence of Overwhelming Postsplenectomy Infection (OPSI) for elective splenectomy, vaccination protocol should be followed. It is important for the clinician to bear in mind the possibility of incidental asymptomatic splenic hydatid cyst and management protocols. Authors, hereby reports, a case of 26-year-old lady with complain of left hypochondriac pain, diagnosed with Ultrasound Sonography (USG) and Contrast Enhanced Computed Tomography (CECT) scan as splenic hydatid cyst. The patient underwent splenectomy after completion of vaccination to avoid OPSI. At six month follow-up the patient was asymptomatic

Treatment and outcomes of an Australian cohort of outpatients with bipolar 1 or schizoaffective disorder over twenty-four months : implications for clinical practice

Background The Bipolar Comprehensive Outcomes Study (BCOS) is a 2-year, prospective, non-interventional, observational study designed to explore the clinical and functional outcomes associated with &lsquo;real-world&rsquo; treatment of participants with bipolar I or schizoaffective disorder. All participants received treatment as usual. There was no study medication.Methods Participants prescribed either conventional mood stabilizers (CMS; n&thinsp;=&thinsp;155) alone, or olanzapine with, or without, CMS (olanzapine&thinsp;&plusmn;&thinsp;CMS; n&thinsp;=&thinsp;84) were assessed every 3&thinsp;months using several measures, including the Young Mania Rating Scale, 21-item Hamilton Depression Rating Scale, Clinical Global Impressions Scale &ndash; Bipolar Version, and the EuroQol Instrument. This paper reports 24-month longitudinal clinical, pharmacological, functional, and socioeconomic data.Results On average, participants were 42 (range 18 to 79) years of age, 58%; were female, and 73%; had a diagnosis of bipolar I. Polypharmacy was the usual approach to pharmacological treatment; participants took a median of 5 different psychotropic medications over the course of the study, and spent a median proportion of time of 100%; of the study on mood stabilizers, 90%; on antipsychotics, 9%; on antidepressants, and 5%; on benzodiazepines/hypnotics. By 24&thinsp;months, the majority of participants had achieved both symptomatic and syndromal remission of both mania and depression. Symptomatic relapse rates were similar for both the CMS alone (65%;) and the olanzapine&thinsp;&plusmn;&thinsp;CMS (61%;) cohorts.Conclusions Participants with bipolar I or schizoaffective disorder in this study were receiving complex medication treatments that were often discordant with recommendations made in contemporary major treatment guidelines. The majority of study participants demonstrated some clinical and functional improvements, but not all achieved remission of symptoms or syndrome.<br /

Phytosomes: A Novel Drug Delivery for Herbal Extracts

The term “phyto” means plant while “some” means cell-like. Phytosome is novel emerging technique applied to phyto-pharmaceutical which contains phytoconstituents to herbal extract surrounds and bound by lipids. Phytosome shows better absorption, hence produces better bioavailability than the conventional herbal extracts. Because of their improved pharmacological and pharmacokinetic properties. Phytosomes are herbal formulation which has enhanced the therapeutic effects of the plant extracts and herbal lead molecule by increasing bioavailability in the target site compared to conventional herbal extracts. This is improved forms of herbal formulation which contain the bioactive phytoconstituents of herb essence enclosed and bound by a lipid. Phytosomes demonstrated improved pharmacokinetic and pharmacodynamic response than customary botanical extracts.&nbsp; Keywords: Phytosomes; Bioavailability, Phospolipids, phytoconstituents.&nbsp;&nbsp;&nbsp

Potential Role of Aromatase over Estrogen Receptor Gene Polymorphisms in Migraine Susceptibility: A Case Control Study from North India

BACKGROUND: The present study was undertaken to find out the role of estrogen pathway related gene polymorphisms in susceptibility to migraine in Northern Indian population. Aromatase, CYP19A1 (rs10046 and rs4646); estrogen receptors, ESR1 (rs2234693, rs1801132, rs2228480 and rs9340799) and ESR2 (rs1271572 and rs1256049) polymorphisms were selected for the present study. METHODOLOGY/PRINCIPAL FINDINGS: The patients were recruited in two cohorts - primary (207) and replicative (127) along with 200 healthy controls and genotyped for various polymorphisms. Logistic regression analysis was applied for statistical analyses. The results were validated in the replicative cohort and pooled by meta analysis using Fisher's and Mantel-Haenszel test. Furthermore, Benjamini - Hochberg false discovery rate test was used to correct for multiple comparisons. CYP19A1 rs10046 and CYP19A1 rs4646 polymorphisms were found to confer risk and protective effect, respectively. Out of four ESR1 polymorphisms, only rs2234693 variant allele was significantly associated in migraine with aura. No significant associations were observed for ESR2 polymorphisms. Significant haplotypes were identified for CYP19A1 and ESR1 polymorphisms. Gene- gene interactions of genotypes as well as haplotypes were observed for CYP19A1- ESR1 showing both risk and protective combinations. CONCLUSION: We strongly suggest CYP19A1 polymorphisms to be the major contributing factors in migraine susceptibility instead of genetic variants of estrogen receptors