IsoDAR@Yemilab: Preliminary Design Report -- Volume I: Cyclotron Driver

This Preliminary Design Report (PDR) describes the IsoDAR electron-antineutrino source. Volumes I and II are site-independent and describe the cyclotron driver providing a 10~mA proton beam, and the medium energy beam transport line and target, respectively. Volume III describes the installation at the Yemilab underground laboratory in South Korea. The IsoDAR driver and target will produce a mole of electron-antineutrinos over the course of five years. Paired with a kton-scale liquid scintillator detector, it will enable an impressive particle physics program including searches for new symmetries, new interactions and new particles. Here in Volume I, we describe the driver, which includes the ion source, low energy beam transport, and cyclotron. The latter features radiofrequency quadrupole (RFQ) direct axial injection and represents the first accelerator purpose-built to make use of vortex motion.Comment: This PDR v0.9 is based on the preceding Conceptual Design Report (CDR) found here: arXiv:1511.05130. As is the nature of technical reports at various design stages (conceptual - preliminary), there is some overlap in tex

Top-down and bottom-up modulation in processing bimodal face/voice stimuli

<p>Abstract</p> <p>Background</p> <p>Processing of multimodal information is a critical capacity of the human brain, with classic studies showing bimodal stimulation either facilitating or interfering in perceptual processing. Comparing activity to congruent and incongruent bimodal stimuli can reveal sensory dominance in particular cognitive tasks.</p> <p>Results</p> <p>We investigated audiovisual interactions driven by stimulus properties (bottom-up influences) or by task (top-down influences) on congruent and incongruent simultaneously presented faces and voices while ERPs were recorded. Subjects performed gender categorisation, directing attention either to faces or to voices and also judged whether the face/voice stimuli were congruent in terms of gender. Behaviourally, the unattended modality affected processing in the attended modality: the disruption was greater for attended voices. ERPs revealed top-down modulations of early brain processing (30-100 ms) over unisensory cortices. No effects were found on N170 or VPP, but from 180-230 ms larger right frontal activity was seen for incongruent than congruent stimuli.</p> <p>Conclusions</p> <p>Our data demonstrates that in a gender categorisation task the processing of faces dominate over the processing of voices. Brain activity showed different modulation by top-down and bottom-up information. Top-down influences modulated early brain activity whereas bottom-up interactions occurred relatively late.</p

[Neurogenic bladder dysfunction a main disability of decompression sickness: a case report].

International audienceINTRODUCTION: Bladder dysfunction is common in the acute phase of decompression sickness and often precedes motor disorders. Few studies have reported the persistence of urinary problems, and no prior reports describe a neurogenic bladder in the primary presentation of decompression sickness. CASE REPORT: We report the case of a 21-year-old female scuba diver with no medical history. After two successive deep dives, dysbaric myelitis developed. The risk factors were foramen ovale and history of diving. The patient initially showed tetraparesia, which was quickly followed by paraparesia with urinary retention. Treatment consisted of recompression with high concentrations of inspired oxygen, aspirin administration and continuous drainage by an indwelling catheter. No lesion was found on 2 sessions of magnetic resonance imaging (MRI) (cerebral and spinal), and somatosensory-evoked potentials were normal. Motor-evoked potential onset latencies were delayed. Neuro-urodynamic investigations revealed detrusor sphincter dysynergia and detrusor overactivity. On quick, complete motor recovery, the patient returned to work and continued with sports (except scuba diving). A year later, she still had urinary and faecal urgencies which were not completely resolved with medication and altered her quality of life. CONCLUSION: Half of the cases of neurological decompression involve dysbaric myelitis. Venous ischemia is the most likely cause. Foramen ovale is an important risk factor, but the pathophysiology is obscure. Bladder problems, common in the acute phase of decompression sickness, may be the primary presentation, and may be prolonged

Somaesthetic perception of the vertical in spinal cord injured patients: A clinical study

AbstractPurposeThe perception of verticality results from the integration of vestibular, visual and somatosensory information. Spinal cord injured patients with complete paraplegia have total somatosensory deafferentation below a certain metameric segment. In our study, we were interested in the implication of somatosensory signal in the construction of verticality and in the possible effect of somatosensory loss on spatial representation.MethodWe analysed haptic and postural aspects of perceived verticality in 14 spinal cord injured patients with complete paraplegia and in an age- and gender-matched group of 13 controls. We also conducted a structured interview on the existence of vertigo or postural instability in daily life.ResultsThe spinal cord injured patients perceived verticality without any significant directional bias in the orientation of the vertical but with a greater uncertainty than control subjects, both in haptic and postural modalities. If paraplegic did not report vertigo, half described an altered spatial perception without vision.ConclusionThe present results confirm the importance of sensory input from the trunk and the lower limbs in the perception of the vertical. However, visual and vestibular information appear to compensate for somatosensory deafferentation

Capsulite rétractile de hanche : à propos de trois cas

Adhesivecapsulitisofthehip(ACH)isduetoretractionof thefibrousjointcapsuleofthehip.Despitethefact thatACH wasfirst describedbyCaroit et al. [2], therehavebeenfew publications on the condition since then [3,8,9,12] and its preciseaetiologyremainsunknown.Lequesneetal.described two kinds of ACH: idiopathicACH (due to diabetes, for example)andsecondaryACH(duetoosteochondromatosis,for example)[8,12].TheclinicalassessmentofACHissimilarto thatforadhesivecapsulitisoftheshoulder(ACS)andfeaturesa combinationof pain and restricted active andpassive joint motion. Thetreatmentcanbepharmacological,physicalorsurgical. Allincases,physiotherapyisessentialforlimitingdeficitsand functional impairments. Thepurposeofthispaperistoreviewthediagnosisofthis underestimated pathology [12] and examine therapeutic strategies.Wepresent threeclinicalcasereports