28 research outputs found
CARATTERISTICHE FARMACOTERAPEUTICHE DEL BENDAZAC E DEL BENDACORTONE
L'effetto biochimico più spiccato del bendazac è la stabilizzazione del colloide proteico, di cui previene la denaturazione. Il bendacortone riunisce in sè gli effetti atidegenerativi del bendazac e le proprità antireattive dei corticosteropidi
Idrogeli a base di policarbossilati sintetici e proteine per il rilascio controllato di farmaci e procedimento per la loro preparazione
Time course of ECG alterations in rats observed after myocardial lesions induced by isoprenaline
Synthetic polycarboxylates and proteins hydrogels for drug sustained release and process for the production thereof
New polymeric hydrogel formulations for the controlled release of protein drugs
Combinations of partial esters of alternating maleic anhydride/mono-methoxyoligoethyleneglycol vinyl ethers copolymers with human serum albumin have been found suitable to give transparent, flexible and coherent films that display a marked hydrogel character and safely pass preliminary "in vitro" and "in vivo" toxicity tests. They have been used in the fabrication of polymeric inserts containing alpha-interferon (IFN(alpha)) by a low temperature casting procedure. Water uptake, dissolution levels, and kinetic release profiles of the active principle from inserts are presented and analyzed in terms of the different extent of hydrophilic interactions of proteins with the synthetic component in the hybrid polymer matrices
