Transitional Interface: Concept, Issues and Framework

Transitional Interfaces have emerged as a new way to interact and collaborate between different interaction spaces such as Reality, Virtual Reality and Augmented Reality. In this paper we explore this concept further. We introduce a descriptive model of the concept, its collaborative aspect and how it can be generalized to describe natural and continuous transitions between contexts (e.g. across space, scale, viewpoint, and representation)

How well do computer-generated faces tap face expertise?

The use of computer-generated (CG) stimuli in face processing research is proliferating due to the ease with which faces can be generated, standardised and manipulated. However there has been surprisingly little research into whether CG faces are processed in the same way as photographs of real faces. The present study assessed how well CG faces tap face identity expertise by investigating whether two indicators of face expertise are reduced for CG faces when compared to face photographs. These indicators were accuracy for identification of own-race faces and the other-race effect (ORE)-the well-established finding that own-race faces are recognised more accurately than other-race faces. In Experiment 1 Caucasian and Asian participants completed a recognition memory task for own- and other-race real and CG faces. Overall accuracy for own-race faces was dramatically reduced for CG compared to real faces and the ORE was significantly and substantially attenuated for CG faces. Experiment 2 investigated perceptual discrimination for own- and other-race real and CG faces with Caucasian and Asian participants. Here again, accuracy for own-race faces was significantly reduced for CG compared to real faces. However the ORE was not affected by format. Together these results signal that CG faces of the type tested here do not fully tap face expertise. Technological advancement may, in the future, produce CG faces that are equivalent to real photographs. Until then caution is advised when interpreting results obtained using CG faces

Western men and Eastern arts: The significance of Eastern martial arts disciplines in British men's narratives of masculinity

Previous Western sociological research on Eastern martial arts has identified a tension between ‘traditional’ Eastern forms of practice and ‘modernized’ Western methods of training and competition. In particular, the ‘sportization’ of Eastern styles, where combat-centred arts based upon moral philosophies have transformed more or less into competitive activities following Western models of rationalized sport, has been an important theme. However, it is also suggested that Eastern martial arts hold special significance in the West for their seemingly esoteric nature. In this regard, such martial arts are considered significant because they are not ‘sports’, but rather disciplines, with fairly different connotations for practitioners. Drawing on interview data, this paper explores how Western practitioners of Eastern martial arts articulate this difference, principally by examining the place of martial artistry in British men's narratives of masculinity. Comparing themselves favourably to assumed, typical visions of Western sporting masculinity, such men draw upon the imagined uniqueness of their martial arts to construct a sense of moral superiority over other men. In so doing, they contribute to a rejection of what they believe to be ‘mainstream’ sporting Western masculinity, thus indicating the role that ‘alternative’ visions of physical culture can play in men's active constructions of gender

The evolution of drug-activated nuclear receptors: one ancestral gene diverged into two xenosensor genes in mammals

BACKGROUND: Drugs and other xenobiotics alter gene expression of cytochromes P450 (CYP) by activating the pregnane X receptor (PXR) and constitutive androstane receptor (CAR) in mammals. In non-mammalian species, only one xenosensor gene has been found. Using chicken as a model organism, the aim of our study was to elucidate whether non-mammalian species only have one or two xenosensors like mammals. RESULTS: To explore the evolutionary aspect of this divergence, we tried to identify additional xenobiotic sensing nuclear receptors in chicken using various experimental approaches. However, none of those revealed novel candidates. Ablation of chicken xenobiotic receptor (CXR) function by RNAi or dominant-negative alleles drastically reduced drug-induction in a chicken hepatoma cell line. Subsequently, we functionally and structurally characterized CXR and compared our results to PXR and CAR. Despite the high similarity in their amino acid sequence, PXR and CAR have very distinct modes of activation. Some aspects of CXR function, e.g. direct ligand activation and high promiscuity are very reminiscent of PXR. On the other hand, cellular localization studies revealed common characteristics of CXR and CAR in terms of cytoplasmic-nuclear distribution. Finally, CXR has unique properties regarding its regulation in comparison to PXR and CAR. CONCLUSION: Our finding thus strongly suggest that CXR constitutes an ancestral gene which has evolved into PXR and CAR in mammals. Future studies should elucidate the reason for this divergence in mammalian versus non-mammalian species

First insights into the ISM at z > 8 with JWST: Possible physical implications of a high [O iii] λ4363/[O iii] λ5007

We present a detailed analysis of the rest-frame optical emission line ratios for three spectroscopically confirmed galaxies at z > 7.5. The galaxies were identified in the James Webb Space Telescope (JWST) Early Release Observations field SMACS J0723.3 - 7327. By quantitatively comparing Balmer and oxygen line ratios of these galaxies with various low-redshift 'analogue' populations (e.g. Green Peas, Blueberries, etc.), we show that no single analogue population captures the diversity of line ratios of all three galaxies observed at z > 7.5. We find that S06355 at z = 7.67 and S10612 at z = 7.66 are similar to local Green Peas and Blueberries. In contrast, S04590 at z = 8.50 appears to be significantly different from the other two galaxies, most resembling extremely low-metallicity systems in the local Universe. Perhaps the most striking spectral feature in S04590 is the curiously high [O iii] λ4363/[O iii] λ5007 ratio (RO3) of 0.048 (or 0.055 when dust-corrected), implying either extremely high electron temperatures, >3 × 104 K, or gas densities >104 cm-3. Observed line ratios indicate that this galaxy is unlikely to host an AGN. Using photoionization modelling, we show that the inclusion of high-mass X-ray binaries or a high cosmic ray background in addition to a young, low-metallicity stellar population can provide the additional heating necessary to explain the observed high RO3 while remaining consistent with other observed line ratios. Our models represent a first step at accurately characterizing the dominant sources of photoionization and heating at very high redshifts, demonstrating that non-thermal processes may become important as we probe deeper into the Epoch of Reionization

Rising from the ashes: evidence of old stellar populations and rejuvenation events in the very early Universe

While JWST has observed galaxies assembling as early as $z\sim14$, evidence of galaxies with significant old stellar populations in the Epoch of Reionisation (EoR) -- the descendants of these earliest galaxies -- are few and far between. Bursty star-formation histories (SFHs) have been invoked to explain the detectability of the earliest UV-bright galaxies, but also to interpret galaxies showing Balmer breaks without nebular emission lines. We present the first spectroscopic evidence of a $z\sim7.9$ galaxy, A2744-YD4, which shows a Balmer break and emission lines, indicating the presence of both a mature and young stellar population. The spectrum of A2744-YD4 shows peculiar emission line ratios suggesting a relatively low ionisation parameter and high gas-phase metallicity. A median stack of galaxies with similar emission line ratios reveals a clear Balmer break in their stacked spectrum. This suggests that a mature stellar population ($\sim 80$ Myr old) has produced a chemically enriched, disrupted interstellar medium. Based on SED-fitting and comparison to simulations, we conclude that the observed young stellar population is in fact the result of a rejuvenation event following a lull in star formation lasting $\sim 20$ Myr, making A2744-YD4 and our stack the first spectroscopic confirmation of galaxies that have rejuvenated following a mini-quenched phase. These rejuvenating galaxies appear to be in an exceptional evolutionary moment where they can be identified. Our analysis shows that a young stellar population of just $\sim 30 \%$ of the total stellar mass would erase the Balmer break. Hence, 'outshining' through bursty SFHs of galaxies in the early Universe is likely plaguing attempts to measure their stellar ages and masses accurately.Comment: 14 pages, 12 figures, 1 table. Submitted to MNRAS. Comments are welcom

Cone-Rod Dystrophy Due to Mutations in a Novel Photoreceptor-Specific Homeobox Gene (CRX) Essential for Maintenance of the Photoreceptor

Genes associated with inherited retinal degeneration have been found to encode proteins required for phototransduction, metabolism, or structural support of photoreceptors. Here we show that mutations in a novel photoreceptor-specific homeodomain transcription factor gene (CRX) cause an autosomal dominant form of cone-rod dystrophy (adCRD) at the CORD2 locus on chromosome 19q13. In affected members of a CORD2-linked family, the highly conserved glutamic acid at the first position of the recognition helix is replaced by alanine (E80A). In another CRD family, a 1 bp deletion (E168 [delta1 bp]) within a novel sequence, the WSP motif, predicts truncation of the C-terminal 132 residues of CRX. Mutations in the CRX gene cause adCRD either by haploinsufficiency or by a dominant negative effect and demonstrate that CRX is essential for the maintenance of mammalian photoreceptorsThis work was supported by the RP Foundation of Canada (R. R. M.), the Foundation Fighting Blindness (R. R. M. and S. G. J.), the Canadian Genetic Disease Network (R. R. M. and A. D.), the Medical Research Council of Canada (R. R. M.), The Wellcome Trust (043825/Z/95) and the Human Genome Mapping Resource Centre (C. Y. G.-E. and S. S. B.), the Howard Hughes Medical Institute and NIH R01 EY0 8064 (C. L. C.), the Canadian Genome Analysis and Technology Genome Resource Facility (S. W. S. and L.-C. T.), the NIH/NEI (EY05627) (S. G. J.), and the Greek National Scholarship Foundation (M. P.). R. R. M. and L.-C. T. are International Research Scholars of the Howard Hughes Medical Institute

JADES : the emergence and evolution of Ly α emission and constraints on the intergalactic medium neutral fraction

The rest-frame UV recombination emission line Lyα can be powered by ionising photons from young massive stars in star-forming galaxies, but the fact that it can be resonantly scattered by neutral gas complicates its interpretation. For reionisation-era galaxies, a neutral intergalactic medium will scatter Lyα from the line of sight, making Lyα a useful probe of the neutral fraction evolution. Here, we explore Lyα in JWST/NIRSpec spectra from the ongoing JADES programme, which targets hundreds of galaxies in the well-studied GOODS-S and GOODS-N fields. These sources are UV-faint (-20.4 < MUV <-16.4) and thus represent a poorly explored class of galaxy. We fitted the low spectral resolution spectra (R ∼ 100) of a subset of 84 galaxies in GOODS-S with zspec > 5.6 (as derived with optical lines) with line and continuum models to search for significant line emission. Through exploration of the R100 data, we find evidence for Lyα in 17 sources. This sample allowed us to place observational constraints on the fraction of galaxies with Lyα emission in the redshift range 5.6 < z < 7.5, with a decrease from z = 6 to z = 7. We also find a positive correlation between the Lyα equivalent width and MUV, as seen in other samples. We used these results to estimate the neutral gas fraction at z ∼ 7, and our estimates are in agreement with previous results (XHI ∼ 0.5-0.9)

JADES : the production and escape of ionizing photons from faint Lyman-alpha emitters in the epoch of reionization

We present the properties of 17 faint Lyman-α emitting galaxies (LAEs) at z > 5.8 from the JWST Advanced Deep Extragalactic Survey (JADES) spectroscopic data in the Hubble Ultra Deep Field/GOODS-S. These LAEs span a redshift range z ≈ 5.8 − 8.0 and a UV magnitude range MUV ≈ −17 to −20.6, with the Lyα equivalent width (EW) in the range ≈25 − 350 Å. The detection of other rest-optical emission lines in the spectra of these LAEs enables the determination of accurate systemic redshifts and Lyα velocity offsets, as well as the physical and chemical composition of their stars and interstellar media. These faint LAEs are consistent with metal-poor systems with high ionization parameters, similar to the general galaxy population at z > 6. We measured an average ionizing photon production efficiency, log(ξion/erg−1 Hz) ≈ 25.57 across our LAEs, which does not evolve strongly with redshift. We report an anti-correlation between the Lyα escape fraction and the velocity offset from systemic redshift, consistent with model expectations. We further find that the strength and velocity offset of Lyα are neither correlated with galaxy spectroscopic properties nor with ξion. We find a decrease in Lyα escape fractions with redshift, indicative of decreasing sizes of ionized bubbles around LAEs at high redshifts. We used a range of galaxy properties to predict Lyman continuum escape fractions for our LAEs, finding that the ionizing photon output into the intergalactic medium from our LAEs remains roughly constant across the observed Lyα EW, showing a mild increase at fainter UV magnitudes and at higher redshifts. We derived correlations between the ionizing photon output from LAEs and their UV magnitudes, Lyα strengths and redshifts, which can be used to constrain the ionizing photon contribution of LAEs at z > 6 towards cosmic reionization