Detecting matter effects in long baseline experiments

Experiments strongly suggest that the flavour mixing responsible for the atmospheric neutrino anomaly is very close to being maximal. Thus, it is of great theoretical as well as experimental importance to measure any possible deviation from maximality. In this context, we reexamine the effects of matter interactions in long baseline neutrino oscillation experiments. Contrary to popular belief, the muon neutrino survival probability is shown to be quite sensitive to matter effects. Moreover, for moderately long baselines, the difference between the survival probilities for $\nu_\mu$ and $\bar\nu_\mu$ is shown to be large and sensitive to the deviation of $|U_{\mu 3}|$ from maximality. Performing a realistic analysis, we demonstrate that a muon-storage ring $\nu$-source alongwith an iron calorimeter detector can measure such deviations. (Contrary to recent claims, this is not so for the NuMI--{\sc minos} experiment.) We also discuss the possible correlation in measuring $U_{\mu 3}$ and $U_{e3}$ in such experiment.Comment: 18 pages, LaTe

Reliability and Feasibility of the Four Square Step Test for Use in Children with Cerebral Palsy: A Pilot Study

Purpose: The ability to maintain standing balance with a moving base of support and while making rapid postural adjustments is important for independence in various functional activities. Clinical tests and measures have not addressed this ability in children with disability. This pilot study examined the feasibility and reliability of the Four Square Step Test (FSST) as a test of dynamic balance in children with cerebral palsy (CP). Method: Four children with CP (Gross Motor Function Classification Scale levels I-II) were tested on the FSST by 3 assessors on the first occasion (interrater reliability) and repeat-tested by 1 assessor after 2 weeks (test-retest reliability). Six children with typical development (TD) were tested on a separate occasion to explore any between-group difference in performance. Results: The FSST was easy to setup, required no specialized equipment, could be completed in 5 minutes, and might be carried out by clinicians with limited experience in pediatric therapy. It demonstrated excellent interrater reliability (ICC = 0.832) and test-retest reliability (ICC = 0.979) in children with CP. Compared with FSST times for children with TD (mean = 9.12 ± 2.67 seconds), times for children with CP (mean = 18.38 ± 9.02 seconds) were significantly slower (p = 0.019, Mann-Whitney U = -2.345). Conclusions and Recommendations: The pilot study provides initial evidence on the potential usefulness of the FSST as a test of dynamic standing balance in children with CP. This warrants further investigation of the clinimetric properties of the FSST using an adequate sample size

Choline transporter-like protein 4 (CTL4) links to non-neuronal acetylcholine synthesis.

Synthesis of acetylcholine (ACh) by non-neuronal cells is now well established and plays diverse physiologic roles. In neurons, the Na(+) -dependent, high affinity choline transporter (CHT1) is absolutely required for ACh synthesis. In contrast, some non-neuronal cells synthesize ACh in the absence of CHT1 indicating a fundamental difference in ACh synthesis compared to neurons. The aim of this study was to identify choline transporters, other than CHT1, that play a role in non-neuronal ACh synthesis. ACh synthesis was studied in lung and colon cancer cell lines focusing on the choline transporter-like proteins, a five gene family choline-transporter like protein (CTL)1-5. Supporting a role for CTLs in choline transport in lung cancer cells, choline transport was Na(+) -independent and CTL1-5 were expressed in all cells examined. CTL1, 2, and 5 were expressed at highest levels and knockdown of CTL1, 2, and 5 decreased choline transport in H82 lung cancer cells. Knockdowns of CTL1, 2, 3, and 5 had no effect on ACh synthesis in H82 cells. In contrast, knockdown of CTL4 significantly decreased ACh secretion by both lung and colon cancer cells. Conversely, increasing expression of CTL4 increased ACh secretion. These results indicate that CTL4 mediates ACh synthesis in non-neuronal cell lines and presents a mechanism to target non-neuronal ACh synthesis without affecting neuronal ACh synthesis

Measurement of Muon Antineutrino Quasi-Elastic Scattering on a Hydrocarbon Target at E_{\nu} ~ 3.5 GeV

We have isolated muon anti-neutrino charged-current quasi-elastic interactions occurring in the segmented scintillator tracking region of the MINERvA detector running in the NuMI neutrino beam at Fermilab. We measure the flux-averaged differential cross-section, d{\sigma}/dQ^2, and compare to several theoretical models of quasi-elastic scattering. Good agreement is obtained with a model where the nucleon axial mass, M_A, is set to 0.99 GeV/c^2 but the nucleon vector form factors are modified to account for the observed enhancement, relative to the free nucleon case, of the cross-section for the exchange of transversely polarized photons in electron-nucleus scattering. Our data at higher Q^2 favor this interpretation over an alternative in which the axial mass is increased.Comment: 8 pages, 5 figures. Added correlation between neutrino and anti-neutrino results in ancillary text files (CSV

Cause-Related Marketing: The Effect of Checkout Charity Requests on Consumer Donation Behavior

The aim of this research was to understand better consumer reactions to donation requests when making point of purchase decisions. A between-subjects full factorial design manipulated product type (goods/services), consumption experience (frivolous/practical), and product/cause fit (strong/weak). In line with prior research (e.g., Chang, 2008; Savary et al, 2015; Strahilevitz & Myers, 1998), a scenario-based approach was employed to assess responses to the CRM manipulations. A total of 241 subjects participated in the study. Our results mirror extant research evidence on the positive effects of pairing frivolous products with donation requests. In that, positive donation behavior largely results as consumers compensate for increased feelings of guilt associated with the frivolous purchase by behaving altruistically toward a needy cause. Moreover, this research is the first to realize a three-way interaction effect based on product type, consumption experience, and product/cause fit. Specifically, we find that the fit between the product and linked cause is more important for practical services and frivolous products than for frivolous services and practical goods. Implications and areas for future research are discussed

Digital Twin in the IoT context: a survey on technical features, scenarios and architectural models

Digital Twin is an emerging concept that is gaining attention in various industries. It refers to the ability to clone a physical object into a software counterpart. The softwarized object, termed logical object, reflects all the important properties and characteristics of the original object within a specific application context. To fully determine the expected properties of the Digital Twin, this paper surveys the state of the art starting from the original definition within the manufacturing industry. It takes into account related proposals emerging in other fields, namely, Augmented and Virtual Reality (e.g., avatars), Multi-agent systems, and virtualization. This survey thereby allows for the identification of an extensive set of Digital Twin features that point to the “softwarization” of physical objects. To properly consolidate a shared Digital Twin definition, a set of foundational properties is identified and proposed as a common ground outlining the essential characteristics (must-haves) of a Digital Twin. Once the Digital Twin definition has been consolidated, its technical and business value is discussed in terms of applicability and opportunities. Four application scenarios illustrate how the Digital Twin concept can be used and how some industries are applying it. The scenarios also lead to a generic DT architectural Model. This analysis is then complemented by the identification of software architecture models and guidelines in order to present a general functional framework for the Digital Twin. The paper, eventually, analyses a set of possible evolution paths for the Digital Twin considering its possible usage as a major enabler for the softwarization process

Measurement of Partonic Nuclear Effects in Deep-Inelastic Neutrino Scattering using MINERvA

The MINERvA collaboration reports a novel study of neutrino-nucleus charged-current deep inelastic scattering (DIS) using the same neutrino beam incident on targets of polystyrene, graphite, iron, and lead. Results are presented as ratios of C, Fe, and Pb to CH. The ratios of total DIS cross sections as a function of neutrino energy and flux-integrated differential cross sections as a function of the Bjorken scaling variable x are presented in the neutrino-energy range of 5 - 50 GeV. Good agreement is found between the data and predicted ratios, based on charged-lepton nucleus scattering, at medium x and low neutrino energies. However, the data rate appears depleted in the vicinity of the nuclear shadowing region, x < 0.1. This apparent deficit, reflected in the DIS cross-section ratio at high neutrino energy , is consistent with previous MINERvA observations and with the predicted onset of nuclear shadowing with the the axial-vector current in neutrino scattering

Internet of things

Manual of Digital Earth / Editors: Huadong Guo, Michael F. Goodchild, Alessandro Annoni .- Springer, 2020 .- ISBN: 978-981-32-9915-3Digital Earth was born with the aim of replicating the real world within the digital world. Many efforts have been made to observe and sense the Earth, both from space (remote sensing) and by using in situ sensors. Focusing on the latter, advances in Digital Earth have established vital bridges to exploit these sensors and their networks by taking location as a key element. The current era of connectivity envisions that everything is connected to everything. The concept of the Internet of Things(IoT)emergedasaholisticproposaltoenableanecosystemofvaried,heterogeneous networked objects and devices to speak to and interact with each other. To make the IoT ecosystem a reality, it is necessary to understand the electronic components, communication protocols, real-time analysis techniques, and the location of the objects and devices. The IoT ecosystem and the Digital Earth (DE) jointly form interrelated infrastructures for addressing today’s pressing issues and complex challenges. In this chapter, we explore the synergies and frictions in establishing an efficient and permanent collaboration between the two infrastructures, in order to adequately address multidisciplinary and increasingly complex real-world problems. Although there are still some pending issues, the identified synergies generate optimism for a true collaboration between the Internet of Things and the Digital Earth