Vocabulary and reading comprehension : instructional effects

Bibliography: leaves 32-34Supported by the National Institute of Educatio

Endothelial preconditioning by transient oxidative stress reduces inflammatory responses of cultured endothelial cells to TNF-α

Brief episodes of ischemia can render an organ resistant to subsequent severe ischemia. This ‘ischemic preconditioning’ is ascribed to various mechanisms, including oxidative stress. We investigated whether preconditioning exists on an endothelial level. Human umbilical vein endothelial cells (HUVECs) were transiently confronted with oxidative stress (1 mM H2O2, 5 min). Adhesion molecules ICAM-1 and E-selectin and release of cytokines IL-6 and IL-8 to subsequent stimulation with TNF-α (2.5 ng/ml, 4 h) were measured (flow cytometry and immunoassay), as were nuclear translocation of the transcription factor NFkB (Western blotting, confocal microscopy) and redox status of HUVECs (quantification of glutathione by HPLC). TNF-α elevated IL-6 in the cell supernatant from 8.8 ± 1 to 41 ± 3 pg/ml and IL-8 from 0.5 ± 0.03 to 3 ± 0.2 ng/ml. ICAM-1 was increased threefold and E-selectin rose eightfold. Oxidative stress (decrease of glutathione by 50%) reduced post-TNF-α levels of IL-6 to 14 ± 3 and IL-8 to 1 ± 0.2; the rise of ICAM-1 was completely blocked and E-selectin was only doubled. The anti-inflammatory effects of preconditioning via oxidative stress were paralleled by reduction of the translocation of NFkB on stimulation with TNF-α, and antagonized by the intracellular radical scavenger N-acetylcysteine. ‘Anti-inflammatory preconditioning’ of endothelial cells by oxidative stress may account for the inhibitory effects of preconditioning on leukocyte adhesion in vivo

Photonic Band Gaps in 3D Network Structures with Short-range Order

We present a systematic study of photonic band gaps (PBGs) in three-dimensional (3D) photonic amorphous structures (PAS) with short-range order. From calculations of the density of optical states (DOS) for PAS with different topologies, we find that tetrahedrally connected dielectric networks produce the largest isotropic PBGs. Local uniformity and tetrahedral order are essential to the formation of PBGs in PAS, in addition to short-range geometric order. This work demonstrates that it is possible to create broad, isotropic PBGs for vector light fields in 3D PAS without long-range order.Comment: 6 pages, 8 figure

Bose Einstein Condensate in a Box

Bose-Einstein condensates have been produced in an optical box trap. This novel optical trap type has strong confinement in two directions comparable to that which is possible in an optical lattice, yet produces individual condensates rather than the thousands typical of a lattice. The box trap is integrated with single atom detection capability, paving the way for studies of quantum atom statistics.Comment: 4 pages, 5 figure

Feshbach resonances in the 6Li-40K Fermi-Fermi mixture: Elastic versus inelastic interactions

We present a detailed theoretical and experimental study of Feshbach resonances in the 6Li-40K mixture. Particular attention is given to the inelastic scattering properties, which have not been considered before. As an important example, we thoroughly investigate both elastic and inelastic scattering properties of a resonance that occurs near 155 G. Our theoretical predictions based on a coupled channels calculation are found in excellent agreement with the experimental results. We also present theoretical results on the molecular state that underlies the 155G resonance, in particular concerning its lifetime against spontaneous dissociation. We then present a survey of resonances in the system, fully characterizing the corresponding elastic and inelastic scattering properties. This provides the essential information to identify optimum resonances for applications relying on interaction control in this Fermi-Fermi mixture.Comment: Submitted to EPJD, EuroQUAM special issues "Cold Quantum Matter - Achievements and Prospects", v2 with updated calibration of magnetic field (+4mG correction) and updated figures 4 and

Процедура и результаты международных сличений эталона РЭМП и государственного эталона РФ

Описана методика процедури та висновки міжнародних двосторонніх звірень еталонів імпульсних електричних та магнітних полів України та Російської Федерації.The method of procedure and conclusions of international two-sided comparisons of standards the pulsed electrical and magnetic fields of Ukraine and Russian Federation is described

Resonator-Enhanced Optical Dipole Trap for Fermionic Lithium Atoms

We demonstrate a novel optical dipole trap which is based on the enhancement of the optical power density of a Nd:YAG laser beam in a resonator. The trap is particularly suited for experiments with ultracold gases, as it combines a potential depth of order 1 mK with storage times of several tens of seconds. We study the interactions in a gas of fermionic lithium atoms in our trap and observe the influence of spin-changing collisions and off-resonant photon scattering. A key element in reaching long storage times is an ultra-low noise laser. The dependence of the storage time on laser noise is investigated.Comment: 4 pages 3 figures Revised 17.07.2001; Corrected calibration of noise measm

Potential Role of Ultrafine Particles in Associations between Airborne Particle Mass and Cardiovascular Health

Numerous epidemiologic time-series studies have shown generally consistent associations of cardiovascular hospital admissions and mortality with outdoor air pollution, particularly mass concentrations of particulate matter (PM) ≤2.5 or ≤10 μm in diameter (PM(2.5), PM(10)). Panel studies with repeated measures have supported the time-series results showing associations between PM and risk of cardiac ischemia and arrhythmias, increased blood pressure, decreased heart rate variability, and increased circulating markers of inflammation and thrombosis. The causal components driving the PM associations remain to be identified. Epidemiologic data using pollutant gases and particle characteristics such as particle number concentration and elemental carbon have provided indirect evidence that products of fossil fuel combustion are important. Ultrafine particles < 0.1 μm (UFPs) dominate particle number concentrations and surface area and are therefore capable of carrying large concentrations of adsorbed or condensed toxic air pollutants. It is likely that redox-active components in UFPs from fossil fuel combustion reach cardiovascular target sites. High UFP exposures may lead to systemic inflammation through oxidative stress responses to reactive oxygen species and thereby promote the progression of atherosclerosis and precipitate acute cardiovascular responses ranging from increased blood pressure to myocardial infarction. The next steps in epidemiologic research are to identify more clearly the putative PM casual components and size fractions linked to their sources. To advance this, we discuss in a companion article (Sioutas C, Delfino RJ, Singh M. 2005. Environ Health Perspect 113:947–955) the need for and methods of UFP exposure assessment