Software Aging Analysis of Web Server Using Neural Networks

Software aging is a phenomenon that refers to progressive performance degradation or transient failures or even crashes in long running software systems such as web servers. It mainly occurs due to the deterioration of operating system resource, fragmentation and numerical error accumulation. A primitive method to fight against software aging is software rejuvenation. Software rejuvenation is a proactive fault management technique aimed at cleaning up the system internal state to prevent the occurrence of more severe crash failures in the future. It involves occasionally stopping the running software, cleaning its internal state and restarting it. An optimized schedule for performing the software rejuvenation has to be derived in advance because a long running application could not be put down now and then as it may lead to waste of cost. This paper proposes a method to derive an accurate and optimized schedule for rejuvenation of a web server (Apache) by using Radial Basis Function (RBF) based Feed Forward Neural Network, a variant of Artificial Neural Networks (ANN). Aging indicators are obtained through experimental setup involving Apache web server and clients, which acts as input to the neural network model. This method is better than existing ones because usage of RBF leads to better accuracy and speed in convergence.Comment: 11 pages, 8 figures, 1 table; International Journal of Artificial Intelligence & Applications (IJAIA), Vol.3, No.3, May 201

Transport in Luttinger Liquids

We give a brief introduction to Luttinger liquids and to the phenomena of electronic transport or conductance in quantum wires. We explain why the subject of transport in Luttinger liquids is relevant and fascinating and review some important results on tunneling through barriers in a one-dimensional quantum wire and the phenomena of persistent currents in mesoscopic rings. We give a brief description of our own work on transport through doubly-crossed Luttinger liquids and transport in the Schulz-Shastry exactly solvable Luttinger-like model.Comment: Latex file, 15 pages, four eps figure

Cross-species amplification of eucalyptus SSR markers in Casuarinaceae

Cross-species amplification of Simple Sequence Repeats (SSRs) loci is considered as a cost-effective approach for developing microsatellite markers for new species.We examined the transferability of eucalyptus SSR loci to the economically important members of the Casuarinaceae family. Ten primer pairs targeting (GA)n, (CTT)n, (TGA)n and (GAA)n motifs were screened in Allocasuarina littoralis, A. luehmannii, Casuarina glauca and C. equisetifolia. Up to 30% of the eucalyptus primer pairs amplified SSRs within Casuarinaceae. Nevertheless, in Allocasuarina no amplification products were observed. In Casuarina species, all the locus specific products were monomorphic while few nonspecific bands also amplified

Divergent Annexin A1 expression in periphery and gut is associated with systemic immune activation and impaired gut immune response during SIV infection.

HIV-1 disease progression is paradoxically characterized by systemic chronic immune activation and gut mucosal immune dysfunction, which is not fully defined. Annexin A1 (ANXA1), an inflammation modulator, is a potential link between systemic inflammation and gut immune dysfunction during the simian immunodeficiency virus (SIV) infection. Gene expression of ANXA1 and cytokines were assessed in therapy-naïve rhesus macaques during early and chronic stages of SIV infection and compared with SIV-negative controls. ANXA1 expression was suppressed in the gut but systemically increased during early infection. Conversely, ANXA1 expression increased in both compartments during chronic infection. ANXA1 expression in peripheral blood was positively correlated with HLA-DR+CD4+ and CD8+ T-cell frequencies, and negatively associated with the expression of pro-inflammatory cytokines and CCR5. In contrast, the gut mucosa presented an anergic cytokine profile in relation to ANXA1 expression. In vitro stimulations with ANXA1 peptide resulted in decreased inflammatory response in PBMC but increased activation of gut lymphocytes. Our findings suggest that ANXA1 signaling is dysfunctional in SIV infection, and may contribute to chronic inflammation in periphery and with immune dysfunction in the gut mucosa. Thus, ANXA1 signaling may be a novel therapeutic target for the resolution of immune dysfunction in HIV infection

Susceptibility Gene Prediction in Hereditary Disease Retinoblastoma

Nowadays Bioinformatics, proteomics and Genomics are the most intriguing sciences to understand the human genome and diseases. Several hereditary genetic diseases like Retinoblastoma involve a sequence of complex interactions between multiple biological processes. With this paper, genetic similarities were found within a selected group of patient\u27s DNA sequences through the use of signal processing tools. DNA, RNA and protein sequences have similarities in structure and function of the gene with their location. In this paper, we introduce a novel method using scoring matrix and wavelet windowing, for the integrative gene prediction. The proposed methods not only integrate multiple genomic data but can be used to predict gene location, gene mutation and genetic disorder from the multi-block genomic data. The performance was assessed by simulation

Effect of polyamines and natural growth substances on the growth and flowering of rose (Rosa hybrida) cv. Samurai under protected conditions

Investigations were conducted to study the effect of different polyamines and natural growth substances as a pre harvest foliar spray on greenhouse rose cv. Samurai. The study involved preharvest foliar spraying with polyamines like spermine (10 ppm) and spermidine (10 ppm); natural growth substances like enriched banana pseudostem sap (1 per cent) and cow urine (2 per cent). All the treatments improved the vegetative and flowering characters over control. However, among different treatments, foliar spray of spermine 10 ppm, followed by spermidine 10 ppm were highly significant in influencing all vegetative parameters like plant height (79 cm), number of branches per plant (3.73), stem girth (10.69 mm), number of leaves per plant (91.33), leaf area (14.68 cm2) and leaf chlorophyll content (36.96 mg/g). Further, flowering parameters like flower stalk length (61.24cm), bud length (2.70mm), flower diameter (6.50 cm), number of petals per flower (55.90) and vase life (6.63 days) were significantly maximum in plants sprayed with spermine 10ppm. The treatment of foliar spray with spermine and spermidine almost doubled the flower production and improved the flower quality in tems of bud size and vase life as compared to control

Effect of various levels of nitrogen on quantitative and qualitative parameters of Rose var. “Top Secret” under poly house condition

Study was conducted to find out the effect of various levels (100, 150, 200, 250,300 mg/plant/week) of nitrogen on growth parameters in terms of qualitative and quantitative traits of rose var. Top Secret. Plant growth in general increased with increase in nitrogen levels. Among various levels of nitrogen application, 300 mg nitrogen per plant per week significantly increased all vegetative growth parameters and showed maximum plant height (117.45 cm), leaf area (98.91 cm2 ) and a number of leaves (62.50). Further, flowering parameters like stalk length (83.53cm), bud diameter (2.45cm), bud length (2.55 cm), number of flowers per plant (7.30) as well as per square meter (53.05) were also significantly maximum in plants given nitrogen @ 300 mg per plant per week. Leaf N (2.94 %), P (0.19%), K (1.87%) and chlorophyll content in leaves (4.41mg/g) was also higher with 300 mg N per plant per week. Vase life (10 days) and anthocyanin content in petal tissue (2.09 mg/g) were found the maximum in plants given nitrogen @ 250 mg per plant per week, which was at par with the treatment of nitrogen @ 300 mg per plant per week. Nitrogen should be applied at the rate of 300 mg/plant/week under protected cultivation as the optimum dose for good plant growth and qualitative flower production in rose var. Top Secret under protected cultivation

PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host-microbe intersection during SIV infection.

Chronic gut inflammatory diseases are associated with disruption of intestinal epithelial barriers and impaired mucosal immunity. HIV-1 (HIV) causes depletion of mucosal CD4+ T cells early in infection and disruption of gut epithelium, resulting in chronic inflammation and immunodeficiency. Although antiretroviral therapy (ART) is effective in suppressing viral replication, it is incapable of restoring the "leaky gut," which poses an impediment for HIV cure efforts. Strategies are needed for rapid repair of the epithelium to protect intestinal microenvironments and immunity in inflamed gut. Using an in vivo nonhuman primate intestinal loop model of HIV/AIDS, we identified the pathogenic mechanism underlying sustained disruption of gut epithelium and explored rapid repair of gut epithelium at the intersection of microbial metabolism. Molecular, immunological, and metabolomic analyses revealed marked loss of peroxisomal proliferator-activated receptor-α (PPARα) signaling, predominant impairment of mitochondrial function, and epithelial disruption both in vivo and in vitro. To elucidate pathways regulating intestinal epithelial integrity, we introduced probiotic Lactobacillus plantarum into Simian immunodeficiency virus (SIV)-inflamed intestinal lumen. Rapid recovery of the epithelium occurred within 5 h of L. plantarum administration, independent of mucosal CD4+ T cell recovery, and in the absence of ART. This intestinal barrier repair was driven by L. plantarum-induced PPARα activation and restoration of mitochondrial structure and fatty acid β-oxidation. Our data highlight the critical role of PPARα at the intersection between microbial metabolism and epithelial repair in virally inflamed gut and as a potential mitochondrial target for restoring gut barriers in other infectious or gut inflammatory diseases

Moral Ideas in Manimegalai

Every period record different types of moral ideas. The special characteristics of morality is found in Tamil literature. There are moral messages in other literature too. Manimegalai is filled with moral ideas. As Manimegalai is a Buddhist scripture, the teachings of virtue and emphasis on virtue is must. Moral ideas are explained in Manimegalai through small short stories. The moral ideas in Manimegalai are very useful. Virtuous actions are necessary for human beings to acquire the best qualities. Likewise, moral thinking is necessary for a man to develop himself to the highest level, to remove bad behavior from him and to become a saint. Human cannot survive without love and virtue. Love and virtue should be the fundamental trait among the people. Manimegalai teaches about the bad qualities found in human beings such as murder, theft, lying and tells people to follow good qualities such as helping the poor and so on. Thus, Manimegalai teaches moral ideas to people and even in today’s education system moral ideas are given important