The influence of energy content during the rearing period on physiological markers and milk yield: A study at monozygotic twins

Using 15 pairs of female monozygotic Holstein Friesian twins that received diets containing different energy contents we repeatedly detected blood biomarkers (insulin, glutamate dehydrogenase, aspartate aminotransferase) and body traits (back fat thickness, daily weight gain). The study reached until the age of 660 days. No effect of a different feeding on milk yield was found. However, the different diet caused effects on daily weight gains, back fat thickness and insulin levels (p<0, 0001). Insulin reached much sooner higher concentrations in the group with intensive feeding than in the group with moderate feeding. Comparing pairs of twins with high (10323 kg) and low (7857 kg) milk yield during the rearing period we found to 37% higher insulin and to 27% lower aspartate aminotransferase levels in the high performance group than in the group with low milk yield. Probably these effects are genetically determined

The influence of energy content during the rearing period on physiological markers and milk yield: A study at monozygotic twins

An 15 genetisch identischen Zwillingspaaren, die energetisch unterschiedlich konzentrierte Futterrationen erhielten, wurden bis zum 660. Lebenstag mehrfach Biomarker im Blut (Insulin, Glutamat-Dehydrogenase, Aspartat-Aminotransferase) und Körpermerkmale (Rückenfettdicke, tägliche Zunahme) erhoben. Fütterungsunterschiede wirkten sich auf die Milchleistung in der ersten Laktation nicht aus. Demgegenüber wurden Rationseffekte für die Merkmale tägliche Zunahme, Rückenfettdicke und Insulin nachgewiesen (p &lt; 0,0001). Der Insulinspiegel erreichte unter den Bedingungen einer intensiven Fütterung in einem wesentlich früheren Alter hohe Werte als bei moderater Fütterung. Der Vergleich zwischen Zwillingspaaren mit hoher (10323 kg) und niedriger (7857 kg) Milchleistung ergab, dass die leistungsüberlegenen Paare während ihrer Aufzucht bis zu 37 % höhere Insulinwerte und bis zu 27 % niedrigere Aktivitäten des Enzyms Aspartat-Aminotransferase aufwiesen. Wahrscheinlich sind genetische Faktoren an der Ausprägung solcher Unterschiede beteiligt.Using 15 pairs of female monozygotic Holstein Friesian twins that received diets containing different energy contents we repeatedly detected blood biomarkers (insulin, glutamate dehydrogenase, aspartate aminotransferase) and body traits (back fat thickness, daily weight gain). The study reached until the age of 660 days. No effect of a different feeding on milk yield was found. However, the different diet caused effects on daily weight gains, back fat thickness and insulin levels (p &lt; 0, 0001). Insulin reached much sooner higher concentrations in the group with intensive feeding than in the group with moderate feeding. Comparing pairs of twins with high (10323 kg) and low (7857 kg) milk yield during the rearing period we found to 37% higher insulin and to 27% lower aspartate aminotransferase levels in the high performance group than in the group with low milk yield. Probably these effects are genetically determined