2,197 research outputs found

    A GeoSocial Intelligence Framework for Studying & Promoting Resilience to Seasonal Flooding in Jakarta, Indonesia

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    PetaJakarta.org is a web-based platform developed to harness the power of social media to gather, sort, and display information about flooding for Jakarta residents in real time. The platform runs on the open source software CogniCity—an OSS platform developed by the SMART Infrastructure Facility, University of Wollongong—which allows data to be collected and disseminated by community members through their location-enabled mobile devices. The project uses a GeoSocial Intelligence Framework to approach the complexity of Jakarta’s entangled hydraulic, hydrological and meteorological systems and thereby converts the noise of social media into knowledge about urban infrastructure and situational conditions related to flooding and inundation. In this paper, PetaJakarta.org co-directors Dr Tomas Holderness, Geomatics Research Fellow at the SMART Infrastructure Facility, Dr Etienne Turpin, Vice-Chancellor’s Postdoctoral Research Fellow at the SMART Infrastructure Facility, and Dr Rohan Wickramasuriyam, GIS Research Fellow at the SMART Infrastructure Facility, will discuss their GeoSocial Intelligence Framework as it applies to their current research in Jakarta. They will also present their preliminary findings from their 2014 Twitter #DataGrant, which has allowed them to develop a correlative analysis between historic social media information, the Jakarta government’s flood maps, and the infrastructure used to manage critical flood emergencies. Finally, they will speculate on several future applications of the CogniCity OSS and suggest how it might be developed to further promote an integrated civic co-management platform with the support of business, industry, government and community organizations

    Phone Selection Through Data Envelopment Analysis

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    Today’s digital era has increased the competition for smart devices tremendously, especially in the mobile phone industry. Each manufacturer is trying to out perform its competitors; therefore these phones are being created with a large amount of attractive features. It is important for consumers to understand these different features while comparing phones to choose the one the best suits his or her own needs. In this paper, we present the findings that compared eight different phones using Data Envelopment Analysis (DEA). Features such as weight, battery power, standby time, and megapixels were considered as outputs, where as the retail price was the input. These input-output data were gathered by researching other similar studies, and then modified according to this specific analysis. As a result we will determine efficiency scores for each mobile device

    New Wine in Old Bottles: A Case Study of Innovation Territories in "New World" Wine Production

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    This article applies the concept of "innovation territories" to explain the recent export success of the Australian Wine Industry. Recent data collected from four "New World" wine producing countries are contrasted in order to investigate "innovation territories" that in the Australian context transcend geographic and policy boundaries. The international comparison shows that these territories can be mapped and their interaction compared. A major finding from teh study is that one of the major contributors to Australia's success in gaining comparative advantage in this industry is the way local and national investments in R&D have transcended geographic and policy boundaries. Coordination driven by strong national policies is required to make this happen. This suggests that "knowledge intensive clusters" driven by national policies can be turned to advantage for regional development. The present study serves to sketch out how the idea of innovation territories might be operationalised for the purpose of future industry policy research

    Gem-induced cytoskeleton remodeling increases cellular migration of HTLV-1-infected cells, formation of infected-to-target T-cell conjugates and viral transmission

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    Efficient HTLV-1 viral transmission occurs through cell-to-cell contacts. The Tax viral transcriptional activator protein facilitates this process. Using a comparative transcriptomic analysis, we recently identified a series of genes up-regulated in HTLV-1 Tax expressing T-lymphocytes. We focused our attention towards genes that are important for cytoskeleton dynamic and thus may possibly modulate cell-to-cell contacts. We first demonstrate that Gem, a member of the small GTP-binding proteins within the Ras superfamily, is expressed both at the RNA and protein levels in Tax-expressing cells and in HTLV-1-infected cell lines. Using a series of ChIP assays, we show that Tax recruits CREB and CREB Binding Protein (CBP) onto a c-AMP Responsive Element (CRE) present in the gem promoter. This CRE sequence is required to drive Tax-activated gem transcription. Since Gem is involved in cytoskeleton remodeling, we investigated its role in infected cells motility. We show that Gem co-localizes with F-actin and is involved both in T-cell spontaneous cell migration as well as chemotaxis in the presence of SDF-1/CXCL12. Importantly, gem knock-down in HTLV-1-infected cells decreases cell migration and conjugate formation. Finally, we demonstrate that Gem plays an important role in cell-to-cell viral transmission

    Los Angeles Summer Midday Particulate Carbon: Primary and Secondary Aerosol

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    Aerosol sampling during photochemically active times across the Los Angeles Basin has provided evidence of secondary formation of organic aerosol from gas-phase precursors at midday. Ambient organic carbon/elemental carbon ratios exceeded the estimated ratio of organic carbon/elemental carbon in primary source emissions on most sampling days at all sites. The concentration of secondary organic aerosol was calculated by using ambient data and estimates of the organic carbon/elemental carbon ratio in primary source emissions. Nonparametric sign correlations comparing calculated secondary organic carbon concentrations with tracers of both primary and secondary aerosols supported the method used to quantify secondary organic carbon. Secondary organic aerosol appears to have contributed roughly half of the organic aerosol in Pasadena during midday summer conditions

    Reverse Shock Emission Revealed in Early Photometry in the Candidate Short GRB 180418A

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    We present observations of the possible short GRB 180418A in γ\gamma-rays, X-rays, and in the optical. Early optical photometry with the TAROT and RATIR instruments show a bright peak (\approx 14.2 AB mag) between T+28T+28 and T+90T+90 seconds that we interpret as the signature of a reversal shock. Later observations can be modeled by a standard forward shock model and show no evidence of jet break, allowing us to constrain the jet collimation to θj>7\theta_j> 7^\circ. Using deep late-time optical observations we place an upper limit of r>24r>24 AB mag on any underlying host galaxy. The detection of the afterglow in the \textit{Swift} UV filters constrains the GRB redshift to z<1.3z<1.3 and places an upper bound on the γ\gamma-ray isotropic equivalent energy Eγ,iso<3×1051E_{\rm{\gamma,iso}} < 3 \times 10^{51} erg. The properties of this GRB (e.g. duration, hardness ratio, energetic, and environment) lie at the intersection between short and long bursts, and we can not conclusively identify its type. We estimate that the probability that it is drawn from the population of short GRBs is 10\%-30\%.Comment: Accepted por publication in Ap

    Glial D-Serine Gates NMDA Receptors at Excitatory Synapses in Prefrontal Cortex.

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    N-methyl-D-aspartate receptors (NMDARs) subserve numerous neurophysiological and neuropathological processes in the cerebral cortex. Their activation requires the binding of glutamate and also of a coagonist. Whereas glycine and D-serine (D-ser) are candidates for such a role at central synapses, the nature of the coagonist in cerebral cortex remains unknown. We first show that the glycine-binding site of NMDARs is not saturated in acute slices preparations of medial prefrontal cortex (mPFC). Using enzymes that selectively degrade either D-ser or glycine, we demonstrate that under the present conditions, D-ser is the principle endogenous coagonist of synaptic NMDARs at mature excitatory synapses in layers V/VI of mPFC where it is essential for long-term potentiation (LTP) induction. Furthermore, blocking the activity of glia with the metabolic inhibitor, fluoroacetate, impairs NMDAR-mediated synaptic transmission and prevents LTP induction by reducing the extracellular levels of D-serine. Such deficits can be restored by exogenous D-ser, indicating that the D-amino acid mainly originates from glia in the mPFC, as further confirmed by double-immunostaining studies for D-ser and anti-glial fibrillary acidic protein. Our findings suggest that D-ser modulates neuronal networks in the cerebral cortex by gating the activity of NMDARs and that altering its levels is relevant to the induction and potentially treatment of psychiatric and neurological disorders

    Formation and dynamics of van der Waals molecules in buffer-gas traps

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    We show that weakly bound He-containing van der Waals molecules can be produced and magnetically trapped in buffer-gas cooling experiments, and provide a general model for the formation and dynamics of these molecules. Our analysis shows that, at typical experimental parameters, thermodynamics favors the formation of van der Waals complexes composed of a helium atom bound to most open-shell atoms and molecules, and that complex formation occurs quickly enough to ensure chemical equilibrium. For molecular pairs composed of a He atom and an S-state atom, the molecular spin is stable during formation, dissociation, and collisions, and thus these molecules can be magnetically trapped. Collisional spin relaxations are too slow to affect trap lifetimes. However, helium-3-containing complexes can change spin due to adiabatic crossings between trapped and untrapped Zeeman states, mediated by the anisotropic hyperfine interaction, causing trap loss. We provide a detailed model for Ag3He molecules, using ab initio calculation of Ag-He interaction potentials and spin interactions, quantum scattering theory, and direct Monte Carlo simulations to describe formation and spin relaxation in this system. The calculated rate of spin-change agrees quantitatively with experimental observations, providing indirect evidence for molecular formation in buffer-gas-cooled magnetic traps.Comment: 20 pages, 13 figure
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