The Douglas-Peucker line simplification algorithm : an introduction with programs

CISRG discussion paper ;

A Wii Bit of Fun: A Novel Platform to Deliver Effective Balance Training to Older Adults

BACKGROUND: Falls and fall-related injuries are symptomatic of an aging population. This study aimed to design, develop, and deliver a novel method of balance training, using an interactive game-based system to promote engagement, with the inclusion of older adults at both high and low risk of experiencing a fall.STUDY DESIGN: Eighty-two older adults (65 years of age and older) were recruited from sheltered accommodation and local activity groups. Forty volunteers were randomly selected and received 5 weeks of balance game training (5 males, 35 females; mean, 77.18 ± 6.59 years), whereas the remaining control participants recorded levels of physical activity (20 males, 22 females; mean, 76.62 ± 7.28 years). The effect of balance game training was measured on levels of functional balance and balance confidence in individuals with and without quantifiable balance impairments.RESULTS: Balance game training had a significant effect on levels of functional balance and balance confidence (P Peer reviewedFinal Published versio

The clumpiness of molecular clouds: HCO+ (3--2) survey near Herbig-Haro objects

Some well-studied Herbig Haro objects have associated with them one or more cold, dense, and quiescent clumps of gas. We propose that such clumps near an HH object can be used as a general measure of clumpiness in the molecular cloud that contains that HH object. Our aim is to make a survey of clumps around a sample of HH objects, and to use the results to make an estimate of the clumpiness in molecular clouds. All known cold, dense, and quiescent clumps near HH objects are anomalously strong HCO+ emitters. Our method is, therefore, to search for strong HCO+ emission as an indicator of a clump near to an HH object. The searches were made using JCMT and SEST in the HCO+ 3-2 and also H13CO+ 1-0 lines, with some additional searches for methanol and sulphur monoxide lines. The sources selected were a sample of 22 HH objects in which no previous HCO+ emission had been detected. We find that half of the HH objects have clumps detected in the HCO+ 3-2 line and that all searches in H13CO$+ 1-0 lines show evidence of clumpiness. All condensations have narrow linewidths and are evidently unaffected dynamically by the HH jet shock. We conclude that the molecular clouds in which these HH objects are found must be highly heterogeneous on scales of less than 0.1 pc. An approximate calculation based on these results suggests that the area filling factor of clumps affected by HH objects is on the order of 10%. These clumps have gas number densities larger than 3e4 cm-2.Comment: 11 pages, 14 figures. Accepted for publication in Astronomy and Astrophysic

Air Pollution Exposure Assessment for Epidemiologic Studies of Pregnant Women and Children: Lessons Learned from the Centers for Children’s Environmental Health and Disease Prevention Research

The National Children’s Study is considering a wide spectrum of airborne pollutants that are hypothesized to potentially influence pregnancy outcomes, neurodevelopment, asthma, atopy, immune development, obesity, and pubertal development. In this article we summarize six applicable exposure assessment lessons learned from the Centers for Children’s Environmental Health and Disease Prevention Research that may enhance the National Children’s Study: a) Selecting individual study subjects with a wide range of pollution exposure profiles maximizes spatial-scale exposure contrasts for key pollutants of study interest. b) In studies with large sample sizes, long duration, and diverse outcomes and exposures, exposure assessment efforts should rely on modeling to provide estimates for the entire cohort, supported by subject-derived questionnaire data. c) Assessment of some exposures of interest requires individual measurements of exposures using snapshots of personal and microenvironmental exposures over short periods and/or in selected microenvironments. d) Understanding issues of spatial–temporal correlations of air pollutants, the surrogacy of specific pollutants for components of the complex mixture, and the exposure misclassification inherent in exposure estimates is critical in analysis and interpretation. e) “Usual” temporal, spatial, and physical patterns of activity can be used as modifiers of the exposure/outcome relationships. f) Biomarkers of exposure are useful for evaluation of specific exposures that have multiple routes of exposure. If these lessons are applied, the National Children’s Study offers a unique opportunity to assess the adverse effects of air pollution on interrelated health outcomes during the critical early life period

Prenatal Insecticide Exposures and Birth Weight and Length among an Urban Minority Cohort

We reported previously that insecticide exposures were widespread among minority women in New York City during pregnancy and that levels of the organophosphate chlorpyrifos in umbilical cord plasma were inversely associated with birth weight and length. Here we expand analyses to include additional insecticides (the organophosphate diazinon and the carbamate propoxur), a larger sample size (n = 314 mother–newborn pairs), and insecticide measurements in maternal personal air during pregnancy as well as in umbilical cord plasma at delivery. Controlling for potential confounders, we found no association between maternal personal air insecticide levels and birth weight, length, or head circumference. For each log unit increase in cord plasma chlorpyrifos levels, birth weight decreased by 42.6 g [95% confidence interval (CI), −81.8 to −3.8, p = 0.03] and birth length decreased by 0.24 cm (95% CI, −0.47 to −0.01, p = 0.04). Combined measures of (ln)cord plasma chlorpyrifos and diazinon (adjusted for relative potency) were also inversely associated with birth weight and length (p < 0.05). Birth weight averaged 186.3 g less (95% CI, −375.2 to −45.5) among newborns with the highest compared with lowest 26% of exposure levels (p = 0.01). Further, the associations between birth weight and length and cord plasma chlorpyrifos and diazinon were highly significant (p ≤ 0.007) among newborns born before the 2000–2001 U.S. Environmental Protection Agency’s regulatory actions to phase out residential use of these insecticides. Among newborns born after January 2001, exposure levels were substantially lower, and no association with fetal growth was apparent (p > 0.8). The propoxur metabolite 2-isopropoxyphenol in cord plasma was inversely associated with birth length, a finding of borderline significance (p = 0.05) after controlling for chlorpyrifos and diazinon. Results indicate that prenatal chlorpyrifos exposures have impaired fetal growth among this minority cohort and that diazinon exposures may have contributed to the effects. Findings support recent regulatory action to phase out residential uses of the insecticides

Morphological aspects of the lead dioxide electrode

The technique of scanning electron microscopy has been used to observe morphological changes occurring in the redox processes involved in the interconversion of lead dioxide and lead sulphate. Observations have been made on lead dioxide films on platinum and pure lead substrates and on one and two dimensional porous lead dioxide electrodes supported either by pure lead or lead-antimony alloys. The morphology of the surfaces examined was found to be strongly affected by their history, particularly their charge/discharge cycles. Lead sulphate formed by the self corrosion process was much more porous than that formed by the electrochemical reduction of lead dioxide. For porous lead dioxide electrodes cycled to a constant response, three well defined regions were found to exist within the electrode. The oxidation of lead sulphate on lead and leadantimony alloys has shown that a duplex layer of lead dioxide existed on the lead-antimony alloys only. The primary layer of lead dioxide found on these alloys was analogous to the single layer on the pure lead electrodes. The observations of the morphological changes occurring in the two dimensional porous elect/ trodes were not consistent with the theory of the macrohomogeneous model for porous lead dioxide, possible interpretations of these results are discussed