Survey and monitoring of opium poppy and wheat in Afghanistan: 2003-2009

An integrated application of remote-sensing technology was devised and applied in Afghanistan during 2003–2009 providing critical information on cereal and poppy cultivation and poppy eradication. The results influenced UK and international policy and counter-narcotics actions in Afghanistan

The application of time-series MODIS NDVI profiles for the acquisition of crop information across Afghanistan

We investigated and developed a prototype crop information system integrating 250 m Moderate Resolution Imaging Spectroradiometer (MODIS) normalized difference vegetation index (NDVI) data with other available remotely sensed imagery, field data, and knowledge as part of a wider project monitoring opium and cereal crops. NDVI profiles exhibited large geographical variations in timing, height, shape, and number of peaks, with characteristics determined by underlying crop mixes, growth cycles, and agricultural practices. MODIS pixels were typically bigger than the field sizes, but profiles were indicators of crop phenology as the growth stages of the main first-cycle crops (opium poppy and cereals) were in phase. Profiles were used to investigate crop rotations, areas of newly exploited agriculture, localized variation in land management, and environmental factors such as water availability and disease. Near-real-time tracking of the current years’ profile provided forecasts of crop growth stages, early warning of drought, and mapping of affected areas. Derived data products and bulletins provided timely crop information to the UK Government and other international stakeholders to assist the development of counter-narcotic policy, plan activity, and measure progress. Results show the potential for transferring these techniques to other agricultural systems

Radical political unionism reassessed

Defections from European social-democratic parties and a resurgence of union militancy have prompted some to diagnose a new left-wing trade unionism across Europe. This comment on the article by Connolly and Darlington scrutinizes trends in France and Germany but primarily analyses recent developments in Britain. While there are some instances of disaffiliation from the Labour Party, support for electoral alternatives, growth in political militancy and emphasis on new forms of internationalism, these have been limited. There is insufficient evidence to suggest that we are witnessing the making of a new radical collectivism

Banks-Zaks fixed point analysis in momentum subtraction schemes

We analyse the critical exponents relating to the quark mass anomalous dimension and beta-function at the Banks-Zaks fixed point in Quantum Chromodynamics (QCD) in a variety of representations for the quark in the momentum subtraction (MOM) schemes of Celmaster and Gonsalves. For a specific range of values of the number of quark flavours, estimates of the exponents appear to be scheme independent. Using the recent five loop modified minimal subtraction (MSbar) scheme quark mass anomalous dimension and estimates of the fixed point location we estimate the associated exponent as 0.263-0.268 for the SU(3) colour group and 12 flavours when the quarks are in the fundamental representation.Comment: 33 latex pages, 25 tables, anc directory contains txt file with electronic version of renormalization group function

Trade unions and the challenge of fostering solidarities in an era of financialisation

This articles re-examines evidence that trade unions in the UK have struggled to renew themselves despite considerable investment of time and effort. It argues that financialisation in the realms of capital accumulation, organisational decision making and everyday life has introduced new barriers to building the solidarities within and between groups of workers that would be necessary to develop a stronger response to the catastrophic effects on labour of financialisation in general, and the financial crisis specifically. The crisis highlighted the weaknesses of trade unions as institutions of economic and industrial democracy, but has also given some opportunities to establish narratives of solidarity in spaces and platforms created within a financialised context

Demographic drivers of decline and recovery in an Afro-Palaearctic migratory bird population

Across Europe, rapid population declines are ongoing in many Afro-Palaearctic migratory bird species, but the development of appropriate conservation actions across such large migratory ranges is severely constrained by lack of understanding of the demographic drivers of these declines. By constructing regional integrated population models (IPMs) for one of the suite of migratory species that is declining in the south-east of Britain but increasing in the north-west, we show that, while annual population growth rates in both regions vary with adult survival, the divergent regional trajectories are primarily a consequence of differences in productivity. Between 1994 and 2012, annual survival and productivity rates ranged over similar levels in both regions, but high productivity rates were rarer in the declining south-east population and never coincided with high survival rates. By contrast, population growth in the north-west was fuelled by several years in which higher productivity coincided with high survival rates. Simulated population trajectories suggest that realistic improvements in productivity could have reversed the decline (i.e. recovery of the population index to ≥ 1) in the south-east. Consequently, actions to improve productivity on European breeding grounds are likely to be a more fruitful and achievable means of reversing migrant declines than actions to improve survival on breeding, passage or sub-Saharan wintering grounds

Age of Barrier Canyon-style rock art constrained by cross-cutting relations and luminescence dating techniques

Rock art compels interest from both researchers and a broader public, inspiring many hypotheses about its cultural origin and meaning, but it is notoriously difficult to date numerically. Barrier Canyon-style (BCS) pictographs of the Colorado Plateau are among the most debated examples; hypotheses about its age span the entire Holocene epoch and previous attempts at direct radiocarbon dating have failed. We provide multiple age constraints through the use of cross-cutting relations and new and broadly applicable approaches in optically stimulated luminescence dating at the Great Gallery panel, the type section of BCS art in Canyonlands National Park, southeastern Utah. Alluvial chronostratigraphy constrains the burial and exhumation of the alcove containing the panel, and limits are also set by our related research dating both a rockfall that removed some figures and the rock’s exposure duration before that time. Results provide a maximum possible age, a minimum age, and an exposure time window for the creation of the Great Gallery panel, respectively. The only prior hypothesis not disproven is a late Archaic origin for BCS rock art, although our age result of A.D. ∼1–1100 coincides better with the transition to and rise of the subsequent Fremont culture. This chronology is for the type locality only, and variability in the age of other sites is likely. Nevertheless, results suggest that BCS rock art represents an artistic tradition that spanned cultures and the transition from foraging to farming in the region. Archaeology is focused upon material records, contextualized in time. Rock art is a record with the potential to provide unique insight into the dynamics and evolution of culture, but it generally lacks stratigraphic or chronologic context. Interpretation of the origin and meaning of rock art is indirect at best, or simply speculative. In the case of some pictographs, pigments may include or have enough accessory carbon for accelerator mass spectrometry (AMS) radiocarbon dating (1⇓⇓–4). In other special situations, such as caves, minimum age constraints have been obtained by various techniques of dating material that overlies or entombs rock art (5⇓–7). However, most rock art remains undatable and researchers rely upon stylistic comparison and indirect associations with artifacts at nearby sites (8, 9). The case in point for this study is arguably the most compelling and debated rock art in the United States—the Barrier Canyon style (BCS) of the Colorado Plateau. Previous attempts to derive an absolute chronology have failed and its age remains unknown, with widely ranging hypotheses that have remained untested until now. The continued development of dating techniques offers new possibilities for hypothesis testing. The optically stimulated luminescence (OSL) signals from mineral grains make it possible to date the deposition of most sediment that is exposed to a few seconds of full sunlight before burial, and its use in the earth and cultural sciences has greatly increased (10, 11). Among the latest applications of OSL are techniques dating the outer surfaces of rock clasts that have become shielded from light, including those with archaeological context (12⇓⇓–15). Recent work has furthermore used the “bleaching” profile of decreasing luminescence signal toward the surface of rock to estimate exposure time to sunlight (16, 17). Using these dating tools, we can constrain the age of rock art and gain new insight into past cultures and landscapes. Here, we synthesize results from three approaches to dating the type section of BCS art, the Great Gallery in Canyonlands National Park of southeastern Utah. Through dating the full alluvial stratigraphy and a rockfall event that both have incontrovertible cross-cutting relations with the rock art, and then by determining the exposure duration of a painted rock surface, we greatly narrow the window of time when the rock art was created. These approaches do not require direct sampling of rock art and have strong potential for application to other archaeological and surface processes research. Although our results are only for the type section of BCS art, and chronological variability should be expected for the style across the region, they suggest that BCS art coincides with the transition to agriculture in the northern Colorado Plateau and may not have been limited to a specific archaeological culture

Adaptive response and enlargement of dynamic range

Many membrane channels and receptors exhibit adaptive, or desensitized, response to a strong sustained input stimulus, often supported by protein activity-dependent inactivation. Adaptive response is thought to be related to various cellular functions such as homeostasis and enlargement of dynamic range by background compensation. Here we study the quantitative relation between adaptive response and background compensation within a modeling framework. We show that any particular type of adaptive response is neither sufficient nor necessary for adaptive enlargement of dynamic range. In particular a precise adaptive response, where system activity is maintained at a constant level at steady state, does not ensure a large dynamic range neither in input signal nor in system output. A general mechanism for input dynamic range enlargement can come about from the activity-dependent modulation of protein responsiveness by multiple biochemical modification, regardless of the type of adaptive response it induces. Therefore hierarchical biochemical processes such as methylation and phosphorylation are natural candidates to induce this property in signaling systems.Comment: Corrected typos, minor text revision

Influence of shot peening on high-temperature corrosion and corrosion-fatigue of nickel based superalloy 720Li

High-temperature corrosion fatigue, a combination of corrosion with a fatigue cycle, is an emerging generic issue affecting power generation and aero gas turbine engines and has the potential to limit component life. Historically, surface treatments, such as shot peening have been used to improve component life and have been optimised for fatigue response. Research into optimisation of shot peening techniques for hot corrosion and high-temperature corrosion fatigue has shown 6–8A 230H 200% coverage to provide overall optimum performance for nickel-based superalloy 720Li based on the limited data within this study. Utilisation of electron backscatter diffraction techniques, in combination with detailed assessment of corrosion products have been undertaken as part of this work. The resultant cold-work visualisation technique provides a novel method of determining the variation in material properties due to the shot peening process and the interaction with hot corrosion. Through this work it has been shown that all three shot peening outputs must be considered to minimise the effect of corrosion fatigue, the cold work, residual stress and surface roughness. Further opportunity for optimisation has also been identified based on this work

Investigating Embryonic Expression Patterns and Evolution of AHI1 and CEP290 Genes, Implicated in Joubert Syndrome

Joubert syndrome and related diseases (JSRD) are developmental cerebello-oculo-renal syndromes with phenotypes including cerebellar hypoplasia, retinal dystrophy and nephronophthisis (a cystic kidney disease). We have utilised the MRCWellcome Trust Human Developmental Biology Resource (HDBR), to perform in-situ hybridisation studies on embryonic tissues, revealing an early onset neuronal, retinal and renal expression pattern for AHI1. An almost identical pattern of expression is seen with CEP290 in human embryonic and fetal tissue. A novel finding is that both AHI1 and CEP290 demonstrate strong expression within the developing choroid plexus, a ciliated structure important for central nervous system development. To test if AHI1 and CEP290 may have co-evolved, we carried out a genomic survey of a large group of organisms across eukaryotic evolution. We found that, in animals, ahi1 and cep290 are almost always found together; however in other organisms either one may be found independent of the other. Finally, we tested in murine epithelial cells if Ahi1 was required for recruitment of Cep290 to the centrosome. We found no obvious differences in Cep290 localisation in the presence or absence of Ahi1, suggesting that, while Ahi1 and Cep290 may function together in the whole organism, they are not interdependent for localisation within a single cell. Taken together these data support a role for AHI1 and CEP290 in multiple organs throughout development and we suggest that this accounts for the wide phenotypic spectrum of AHI1 and CEP290 mutations in man