221 research outputs found
XIPE: the X-ray Imaging Polarimetry Explorer
X-ray polarimetry, sometimes alone, and sometimes coupled to spectral and
temporal variability measurements and to imaging, allows a wealth of physical
phenomena in astrophysics to be studied. X-ray polarimetry investigates the
acceleration process, for example, including those typical of magnetic
reconnection in solar flares, but also emission in the strong magnetic fields
of neutron stars and white dwarfs. It detects scattering in asymmetric
structures such as accretion disks and columns, and in the so-called molecular
torus and ionization cones. In addition, it allows fundamental physics in
regimes of gravity and of magnetic field intensity not accessible to
experiments on the Earth to be probed. Finally, models that describe
fundamental interactions (e.g. quantum gravity and the extension of the
Standard Model) can be tested. We describe in this paper the X-ray Imaging
Polarimetry Explorer (XIPE), proposed in June 2012 to the first ESA call for a
small mission with a launch in 2017 but not selected. XIPE is composed of two
out of the three existing JET-X telescopes with two Gas Pixel Detectors (GPD)
filled with a He-DME mixture at their focus and two additional GPDs filled with
pressurized Ar-DME facing the sun. The Minimum Detectable Polarization is 14 %
at 1 mCrab in 10E5 s (2-10 keV) and 0.6 % for an X10 class flare. The Half
Energy Width, measured at PANTER X-ray test facility (MPE, Germany) with JET-X
optics is 24 arcsec. XIPE takes advantage of a low-earth equatorial orbit with
Malindi as down-link station and of a Mission Operation Center (MOC) at INPE
(Brazil).Comment: 49 pages, 14 figures, 6 tables. Paper published in Experimental
Astronomy http://link.springer.com/journal/1068
A comparison between ilioinguinal and modified Stoppa approach in anterior column acetabular fractures
Introduction: Pelvis fractures are among the most difficult fractures to manage and treat for Orthopedic surgeons. Anatomic reduction is the main goal to reach in the acetabular fractures' treatment. The following study compares clinical outcomes and complications of Ilioinguinal versus modified Stoppa approach in Open Reduction and Internal Fixation (ORIF) of anterior column acetabulum fractures. Materials and methods: A comparative analysis on 90 patients undergoing ORIF on acetabular fracture has been performed. Patients have been divided into two groups. The first group was treated by Ilioinguinal approach (n = 48), the second group by modified Stoppa approach (n = 42). The following parameters have been compareted: quality of fragment reduction; operative time; peri‐ and post-operative blood loss; complications; clinical and radiographic outcomes. Results: The modified Stoppa approach has shown a shorter mean operative time (146 min vs 175 min), fewer complications (14/48 vs 6/42), less blood loss both in the perio-operative phase (0.8 Hb pt vs 1.3 Hb pt) than in postoperative one (1.1 Hb pt vs 1.5 Hb pt), a lower rate of nerve, infections and critical complications. On the other hand, the ilioinguinal approach has showed better results in terms of quality of fracture reduction (43/48 patiens with anatomical or near anatomical reduction vs. 37/42). No significant differences concerning vascular lesions, clinical and functional outcomes have been found between the two groups. Conclusions: The modified Stoppa approach results in shorter operative time, less intra-operative blood loss and fewer complications than the ilioinguinal one. Greater anatomic reduction is achieved by Ilioinguinal approach; however, this does not necessarily translate into better clinical and functional outcomes which, overall, are comparable in the two analysed approaches. In conclusion, the modified Stoppa approach is deemed to be a better alternative in treating these fractures
Cardiovascular remodeling is greater in isolated systolic hypertension than in diastolic hypertension in older adults: The Insufficienza Cardiaca negli Anziani Residenti (ICARE) a Dicomano study.
Dystonia Linked to EIF4A2 Haploinsufficiency: A Disorder of Protein Translation Dysfunction
Background: Protein synthesis is a tightly controlled process, involving a host of translation-initiation factors and microRNA-associated repressors. Variants in the translational regulator EIF2AK2 were first linked to neurodevelopmental-delay phenotypes, followed by their implication in dystonia. Recently, de novo variants in EIF4A2, encoding eukaryotic translation initiation factor 4A isoform 2 (eIF4A2), have been described in pediatric cases with developmental delay and intellectual disability. Objective: We sought to characterize the role of EIF4A2 variants in dystonic conditions. Methods: We undertook an unbiased search for likely deleterious variants in mutation-constrained genes among 1100 families studied with dystonia. Independent cohorts were screened for EIF4A2 variants. Western blotting and immunocytochemical studies were performed in patient-derived fibroblasts. Results: We report the discovery of a novel heterozygous EIF4A2 frameshift deletion (c.896_897del) in seven patients from two unrelated families. The disease was characterized by adolescence- to adulthood-onset dystonia with tremor. In patient-derived fibroblasts, eIF4A2 production amounted to only 50% of the normal quantity. Reduction of eIF4A2 was associated with abnormally increased levels of IMP1, a target of Ccr4-Not, the complex that interacts with eIF4A2 to mediate microRNA-dependent translational repression. By complementing the analyses with fibroblasts bearing EIF4A2 biallelic mutations, we established a correlation between IMP1 expression alterations and eIF4A2 functional dosage. Moreover, eIF4A2 and Ccr4-Not displayed significantly diminished colocalization in dystonia patient cells. Review of international databases identified EIF4A2 deletion variants (c.470_472del, c.1144_1145del) in another two dystonia-affected pedigrees. Conclusions: Our findings demonstrate that EIF4A2 haploinsufficiency underlies a previously unrecognized dominant dystonia-tremor syndrome. The data imply that translational deregulation is more broadly linked to both early neurodevelopmental phenotypes and later-onset dystonic conditions. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society
Observations of 4U 1626-67 with the Imaging X-ray Polarimetry Explorer
We present measurements of the polarization of X-rays in the 2-8 keV band
from the pulsar in the ultracompact low mass X-ray binary 4U1626-67 using data
from the Imaging X-ray Polarimetry Explorer (IXPE). The 7.66 s pulsations were
clearly detected throughout the IXPE observations as well as in the NICER soft
X-ray observations, which we use as the basis for our timing analysis and to
constrain the spectral shape over 0.4-10 keV energy band. Chandra HETGS
high-resolution X-ray spectra were also obtained near the times of the IXPE
observations for firm spectral modeling. We find an upper limit on the
pulse-averaged linear polarization of <4% (at 95% confidence). Similarly, there
was no significant detection of polarized flux in pulse phase intervals when
subdividing the bandpass by energy. However, spectropolarimetric modeling over
the full bandpass in pulse phase intervals provide a marginal detection of
polarization of the power-law spectral component at the 4.8 +/- 2.3% level (90%
confidence). We discuss the implications concerning the accretion geometry onto
the pulsar, favoring two-component models of the pulsed emission.Comment: 19 pages, 7 figures, 7 tables; accepted for publication in the
Astrophysical Journa
IXPE and XMM-Newton observations of the Soft Gamma Repeater SGR 1806-20
Recent observations with the Imaging X-ray Polarimetry Explorer (IXPE) of two
anomalous X-ray pulsars provided evidence that X-ray emission from magnetar
sources is strongly polarized. Here we report on the joint IXPE and XMM-Newton
observations of the soft {\gamma}-repeater SGR 1806-20. The spectral and timing
properties of SGR 1806-20 derived from XMM-Newton data are in broad agreement
with previous measurements; however, we found the source at an all-time-low
persistent flux level. No significant polarization was measured apart from the
4-5 keV energy range, where a probable detection with PD=31.6\pm 10.5% and
PA=-17.6\pm 15 deg was obtained. The resulting polarization signal, together
with the upper limits we derive at lower and higher energies 2-4 and 5-8 keV,
respectively) is compatible with a picture in which thermal radiation from the
condensed star surface is reprocessed by resonant Compton scattering in the
magnetosphere, similar to what proposed for the bright magnetar 4U 0142+61.Comment: 11 pages, 3 figures, accepted for publication in Ap
Pulsar-wind-nebula-powered Galactic center X-ray filament G0.13–0.11
We report the discovery of X-ray polarization from the X-ray-bright filament G0.13−0.11 in the Galactic center (GC) region. This filament features a bright, hard X-ray source that is most plausibly a pulsar wind nebula (PWN) and an extended and structured diffuse component. Combining the polarization signal from IXPE with the imaging/spectroscopic data from Chandra, we find that X-ray emission of G0.13−0.11 is highly polarized PD = 57(±18)% in the 3−6 keV band, while the polarization angle is PA = 21 ° ( ± 9 ° ). This high degree of polarization proves the synchrotron origin of the X-ray emission from G0.13−0.11. In turn, the measured polarization angle implies that the X-ray emission is polarized approximately perpendicular to a sequence of nonthermal radio filaments that may be part of the GC Radio Arc. The magnetic field on the order of 100 μG appears to be preferentially ordered along the filaments. The above field strength is the fiducial value that makes our model self-consistent, while the other conclusions are largely model independent
Evidence for a shock-compressed magnetic field in the northwestern rim of Vela Jr. from X-ray polarimetry
Synchrotron X-ray emission has been detected from nearly a dozen young supernova remnants (SNRs). X-rays of synchrotron origin exhibit linear polarization in a regular, non-randomly oriented magnetic field. The significant polarized X-ray emission from four such SNRs has already been reported on the basis of observations with the Imaging X-ray Polarimetry Explorer (IXPE). The magnetic-field structure as derived from IXPE observations is radial for Cassiopeia A, Tycho's SNR, and SN 1006, and tangential for RX J1713.7-3946. The latter together with the recent detection of a tangential magnetic field in SNR 1E 0102.2-7219 by the Australia Telescope Compact Array in the radio band shows that tangential magnetic fields can also be present in young SNRs. Thus, the dichotomy in polarization between young and middle-aged SNRs (radial magnetic fields in young SNRs, but tangential magnetic fields in middle-aged SNRs), previously noticed in the radio band, deserves additional attention. The present analysis of IXPE observations determines, for the first time, a magnetic-field structure in the northwestern rim of Vela Jr, also known as RX J0852.0-4622, and provides a new example of a young SNR with a tangential magnetic field
Discovery of a Shock-compressed Magnetic Field in the Northwestern Rim of the Young Supernova Remnant RX J1713.7–3946 with X-Ray Polarimetry
Supernova remnants (SNRs) provide insights into cosmic-ray acceleration and magnetic field dynamics at shock fronts. Recent X-ray polarimetric measurements by the Imaging X-ray Polarimetry Explorer (IXPE) have revealed radial magnetic fields near particle acceleration sites in young SNRs, including Cassiopeia A, Tycho, and SN 1006. We present here the spatially resolved IXPE X-ray polarimetric observation of the northwestern rim of SNR RX J1713.7–3946. For the first time, our analysis shows that the magnetic field in the particle acceleration sites of this SNR is oriented tangentially with respect to the shock front. Because of the lack of precise Faraday rotation measurements in the radio band, this was not possible before. The average measured polarization degree (PD) of the synchrotron emission is 12.5% ± 3.3%, lower than the one measured by IXPE in SN 1006, comparable to the Tycho one, but notably higher than the one in Cassiopeia A. On subparsec scales, localized patches within RX J1713.7–3946 display a PD of up to 41.5% ± 9.5%. These results are compatible with a shock-compressed magnetic field. However, in order to explain the observed PD, either the presence of a radial net magnetic field upstream of the shock or partial reisotropization of the turbulence downstream by radial magnetohydrodynamical instabilities can be invoked. From comparison of PD and magnetic field distribution with γ-rays and 12CO data, our results provide new inputs in favor of a leptonic origin of the γ-ray emission
The Polarized Cosmic Hand: IXPE Observations of PSR B1509-58/MSH 15-52
We describe IXPE polarization observations of the Pulsar Wind Nebula (PWN)
MSH15-52, the `Cosmic Hand'. We find X-ray polarization across the PWN, with B
field vectors generally aligned with filamentary X-ray structures. High
significance polarization is seen in arcs surrounding the pulsar and toward the
end of the `jet', with polarization degree PD>70%, thus approaching the maximum
allowed synchrotron value. In contrast, the base of the jet has lower
polarization, indicating a complex magnetic field at significant angle to the
jet axis. We also detect significant polarization from PSR B1509-58 itself.
Although only the central pulse-phase bin of the pulse has high individual
significance, flanking bins provide lower significance detections and, in
conjunction with the X-ray image and radio polarization, can be used to
constrain rotating vector model solutions for the pulsar geometry.Comment: To appear in the Astrophysical Journa
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