Facile, Inexpencive Synthesis of 4-Oxo-carboxylic Acids from Primary Aliphatic Nitrocompounds and 2-Propenal

4-Oxoalkanoic acids, useful organic compounds, are easily prepared by conjugate addition of primary aliphatic nitro compounds to acrolein on alumina surface, in the absence of a solvent, and subsequent oxidation with hydrogen peroxide/potassium carbonate

A Simple synthesis of Methyl-7-Oxoheptanoate

Methyl 7-Oxoheptanoate has recently been used for the synthesis of 2-(6-methoxycarbonylhexyl)-cyclopent-2-en-l-one, a key intermediate for preparation of the pros tanoids! Several methods have been previously adop 3 ted to prepare the title compound: from cycloheptanone, from 1 -methoxycycloheptenef from suberic acid: from methyl 7-iodoheptanoate6,and from 6-bromohexanoic acid or 7 from E-caprolactone

Reduction of Aliphatic and Aromatic Nitro Compounds with Sodium Borohydride in THF using 10% Pd/C as Catalyst: a New and Efficient Method."

Aliphatic and aromatic nitro compounds are reduced to amino compounds in good yields with sodium borohydride in tetrahydrofuran using 10% palladium-on-carbon as catalyst

A Tandem Denitration-Deoxygenation of α-Nitro Ketones via p-Toluenesulfonylhydrazones with Lithium Aluminium Hydride: A Practical Synthesis of (Z)-9-Tricosene, the Sex Pheromone of the Housefly (Musca Domestica).

A Tandem Denitration-Deoxygenation of α-Nitro Ketones via p-Toluenesulfonylhydrazones with Lithium Aluminium Hydride: A Practical Synthesis of (Z)-9-Tricosene, the Sex Pheromone of the Housefly (Musca Domestica)

Ring Cleavage of Cyclic 2-Nitroketones by KF Catalyst: A General Synthesis of ω-Nitroacids and ω-Nitroesters

Preparation of ω-nitroacids and ω-nitroesters has been achieved by ring cleavage of 2-nitrocycloalkanones, under basic condition (KF), in water (THF solution) or alcohol

An Improved Synthesis of Methyl or Ethyl 7-Oxoheptanoate and 7-Acetoxyheptanal

Reaction of cycloheptanone with potassium persulfate, in ethanol or methanol, gave ethyl or methyl 7-hydroxyheptanoate which, by oxidation with PCC, were converted into ethyl or methyl 7-oxoheptanoate in good yields. Protection of aldehyde group of methyl 7-oxoheptanoate, followed by one-step conversion of carboxylic ester to the acetate gave, after regeneration of aldehyde group, 7-acetoxyheptanal

(Z)-7-Nitro-3-Heptene as Central Intermediate for the Synthesis of Jasmone,Methyl Jasmonate and γ-Jasmolactone."

(Z)-7-Nitro-3-heptene is used as central intermediate in the synthesis of jasmone (13), methyl jasmonate (15), and γ-jasmolactone (16), three jasmin constituents. Conjugate addition of the title nitro compound, by heterogeneous catalysis, to methyl vinyl ketone, or acrolein, or methyl acrylate, followed by Nef reaction, affords (Z)-undec-8-ene-2,5-dione, (Z)-1,4-dioxodec-7-ene, and (Z)-4-oxo-dec-7-enoic acid methyl ester respectively, which are easily converted into jasmone, methyl jasmonate and γ -jasmolactone

Oxidative Conversion of Aliphatic Nitrocompounds to Carbonyls using Sodium Chlorite

Aliphatic Nitrocompounds are converted to corresponding Carbonyls by means of Sodium Chlorite under phase transfer catalysis conditions (CH2Cl2-NaOH-1N-Bu4NHSO4). Primary nitrocompounds give aldehydes while secondary nitroalkanes give ketones in good yield

A Convenient Syntesis of 1-(2-Furyl)-2-nitroalk-1-enes on Alumina Surface without Solvent

Condensation of furylaldehydes with nitroalkanes in the presence of alumina directly affords the corresponding nitroalkenes in good yields

A Nitrone-Based Approach to the Enantioselective Total Synthesis of (–)-Anisomycin

This paper describes a new synthetic approach to (-)-anysomycin in which the crucial step is an organomagnesium addition to a chiral nitrone