1,882 research outputs found
Forgotten, recollected, forgotten…
The experience of reminiscences/dreams lies at the roots of the theory of individual and social memory. The author compares childhood remembrance-pictures of the two important events of 28 June 1956 in Poznań with documental photographs collected in the Museum of Poznań Uprising 1956. These traces-documents are apparently different in comparison with tablets fitted on the pavement leading to the Museum. Memory is plural, and there are three main levels of recognition, memory and forgetting discussed by the author.The experience of reminiscences/dreams lies at the roots of the theory of individual and social memory. The author compares childhood remembrance-pictures of the two important events of 28 June 1956 in Poznań with documental photographs collected in the Museum of Poznań Uprising 1956. These traces-documents are apparently different in comparison with tablets fitted on the pavement leading to the Museum. Memory is plural, and there are three main levels of recognition, memory and forgetting discussed by the author
Incidence of type 1 diabetes has doubled in Kuwaiti children 0-14 years over the last 20 years
Aims: This study had 2 aims: to report data on the incidence of childhood-onset type 1 diabetes in Kuwaiti children aged 0-14 years during 2011 to 2013 and to compare the recent data with those collected during 1992 to 1997.Methods: All newly diagnosed patients were registered through the Childhood-Onset Diabetes eRegistry (CODeR) in 2011-2013, based on the DiaMond protocol used in 1992-1997.Results: A total of 515 Kuwaiti children (247 boys and 268 girls) aged 0-14 years newly diagnosed with type 1 diabetes were registered from 1 January 2011 to 31 December 2013. Data ascertainment were 96.7%. The mean age ± SD at diagnosis was 8.7 ± 3.4 years in boys and 7.9 ± 3.1 years in girls. The crude incidence rate (95% CI) was 40.9 (37.4-44.6) and the age standardized rate 41.7 (95% 38.1-45.4) per 100,000 per year, 39.3 (34.6-44.4) among boys and 44.1 (39.0-49.7) among girls. A statistically significant increasing trend in incidence was observed as the overall crude incidence rose from 17.7 in 1992-1994 to 40.9 per 100,000 per year in 2011-2013. The Poisson regression model depicting the trend in incidence revealed that, the incidence rates adjusted for age and sex in 2011 to 2013 was 2.3 (95% CI 1.9-2.7) times higher than 1992-1997.Conclusions: The incidence of type 1 diabetes in Kuwaiti children 0-14 years has doubled in the last 2 decades. The reasons for this increase requires further investigation.</p
Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants
Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants
Background: The majority of coeliac disease (CD) patients are not being properly diagnosed and therefore remain untreated, leading to a greater risk of developing CD-associated complications. The major genetic risk heterodimer, HLA-DQ2 and DQ8, is already used clinically to help exclude disease. However, approximately 40% of the population carry these alleles and the majority never develop CD. Objective: We explored whether CD risk prediction can be improved by adding non-HLA-susceptible variants to common HLA testing. Design: We developed an average weighted genetic risk score with 10, 26 and 57 single nucleotide polymorphisms (SNP) in 2675 cases and 2815 controls and assessed the improvement in risk prediction provided by the non-HLA SNP. Moreover, we assessed the transferability of the genetic risk model with 26 non-HLA variants to a nested case–control population (n=1709) and a prospective cohort (n=1245) and then tested how well this model predicted CD outcome for 985 independent individuals. Results: Adding 57 non-HLA variants to HLA testing showed a statistically significant improvement compared to scores from models based on HLA only, HLA plus 10 SNP and HLA plus 26 SNP. With 57 non-HLA variants, the area under the receiver operator characteristic curve reached 0.854 compared to 0.823 for HLA only, and 11.1% of individuals were reclassified to a more accurate risk group. We show that the risk model with HLA plus 26 SNP is useful in independent populations. Conclusions: Predicting risk with 57 additional non-HLA variants improved the identification of potential CD patients. This demonstrates a possible role for combined HLA and non-HLA genetic testing in diagnostic work for CD
Co studentyfikacja ma wspólnego z gentryfikacją?
This paper explores the phenomenon of studentification in the UK and Poland. More specifically, the paper illustrates cultural base of conflicts and debates connected with studentification and methods of its researching. It is argued that there is a difference between geographers and cultural urban studies vision of student communities and the geographical, economic, social and culturaleffects of the promotion of higher education in the end of 20th century. Studentification generate gentrification, but it has also a positive impact on city dwellers and local communities. Enlarged student populations should be integrated into communities characterized by much the same styles of life, modes of consumption, inherited cultural capital and “good taste”. Students are dispersed to different parts of towns and cities. These new tendencies in student population may foster resentment and conflict between students and established residents. It is asserted that the impact of cultural factors could not be the most important for the residential geographies of students, however they are crucial for characteristic of such concepts like studenthood and studentland, closely tight with the very notion of studentification. They are a factor in the rise of studentification and the mobility of established communities. It is argued that these young communities signified lucid exemplars that the city-university relations seek to engender. The paper concludes by considering some possible issues of studentification in the field of cultural urban studies.Studentyfikacja jest pojęciem nowym i rzadko wykorzystywanym w badaniach prowadzonych w Polsce. Wiąże się, a także proces miejski, który opisuje, z rewitalizacją miast i negatywną jej konsekwencją, czyli gentryfikacją. Przebieg studentyfikacji uzależniony jest od czynników: ekonomicznych, politycznych, demograficznych, społecznych, kulturowych. Przedmiotem artykułu jest tylko ta ostatnia, lecz jej pełne oddzielenie od pozostałych nie jest możliwe. Dotyczy to rozpoznania wkładu studentów w organizację nowych form i miejsc konsumpcji kulturowej skierowanych przede wszystkim, lecz nie tylko, do nich samych. Wynikiem takich działań jest coraz większa widoczność studentów w krajobrazie śródmiejskim oraz kształtowanie się nowej miejskiej kultury opartej nie tyle na wariancie gustu klasowego (P. Bourdieu), ile na bardziej płynnej kategorii, za jaką uważam gust studencki
Zamiast wspólnoty
This article introduces the concept of urban sociability by first examining the various uses of term ‘community’ and explaining why community in urban context could be the nebulous and vague concept. The term community often does imply social practices and ties which are anti-urban in such. Sometimes, however, urban community is defined in a way that suggests its utopian character. This inconvenient flexibility of urban community concept might be a chance to introduce another concept of urban sociability as the reason and quality of cityness. If we defined urban sociability from the Georg Simmel point of view, we would have a definition that largely agrees with most of the observations and experiences in urban space. The areas of the urban sociability I call urban salons. By comparing a few of Chicago salons, I show how urban sociability concept compets with a community theory tradition.W artykule wprowadzone zostaje pojęcie miejskiej towarzyskości, poprzedzone oceną różnych użyć terminu „wspólnota” i wykazaniem, dlaczego wspólnota w miejskim kontekście staje się pojęciem mgławicowym i mało precyzyjnym. Termin ten często implikuje praktyki i więzi społeczne, które w istocie są antymiejskie. Bywa jednak, że miejską wspólnotę definiuje się w sposób sugerujący jej utopijny charakter. Tę niewygodną elastyczność pojęcia miejskiej wspólnoty można uznać za okazję do wprowadzenia innego pojęcia – miejskiej towarzyskości – jako przyczyny i jakości tego, co miejskie. Jeśli definiujemy miejską towarzyskość z punktu widzenia Simmla, uzyskamy definicję w znacznym stopniu odpowiadającą obserwacjom i doświadczeniom w przestrzeni miejskiej. Przestrzenie miejskiej towarzyskości nazywam miejskimi salonami. Porównując kilka salonów Chicago, pokazuję, w jaki sposób pojęcie miejskiej towarzyskości konkuruje z tradycją teorii wspólnoty
Miejsce podmiotu - podmiot jako miejsce. Kto wyprowadza podmiot z metafizyki?
The Position of the Subject - The Subject as Position. Who Leads the Subject out of Metaphysics? Abstract in English The essay attempts to answer three basic questions. Who leads the subject out of metaphysics? Who occupies \u27my\u27 position? What passes through the position called the subject? The first of these questions concerns the current tasks of the philosophy of subjectivity; the second one addresses the subject\u27s functions in different traditions with particular emphasis on the incommensurability of Greek and Judaic traditions; and the third question is concerned with the effects of poststructuralist de-re-constructions of the subject.The Position of the Subject - The Subject as Position. Who Leads the Subject out of Metaphysics? Abstract in English The essay attempts to answer three basic questions. Who leads the subject out of metaphysics? Who occupies \u27my\u27 position? What passes through the position called the subject? The first of these questions concerns the current tasks of the philosophy of subjectivity; the second one addresses the subject\u27s functions in different traditions with particular emphasis on the incommensurability of Greek and Judaic traditions; and the third question is concerned with the effects of poststructuralist de-re-constructions of the subject
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