142 research outputs found
Anatomy of a mixed-influence shelf edge delta, Karoo Basin, South Africa
The position and process regime of paralic systems relative to the shelf edge rollover is a major control on sediment transfer into deep water. The depositional strike and dip variability of an exhumed Permian shelf edge succession has been studied in the Paardeberg Ridge, Karoo Basin. Siltstone-rich slope turbidites are overlain by 25–75 m-thick prodelta parasequences. These are truncated by a 30 m-thick sandstone-prone unit of tabular or convex-topped sandstones, interpreted as wave-modified mouth bars, cut by multiple irregular concave-upwards erosive surfaces overlain by sandstones, interpreted as distributary channels. The stratigraphic context, lithofacies and architecture are consistent with a mixed-influence shelf edge delta; the erosional base to the unit marks a basinwards shift in facies, consistent with a sequence boundary. Channels become thicker, wider, more erosive and incise into deeper-water facies downdip and correlate with sandstone-rich upper slope turbidites, all of which support the bypass of sand across the rollover. The overall progradational stacking pattern results in a stratigraphic decrease in channel dimensions. The results of this study suggest a predictable relationship between channel geometry, facies and position on the shelf-to-slope profile under a mixed wave and fluvial process regime
Carcinoma developing in a fibroadenoma in a woman with a family history of breast cancer: a case report and review of literature
Transmasculine individuals’ experiences with lactation, chestfeeding, and gender identity: a qualitative study
Review of juxtaglomerular cell tumor with focus on pathobiological aspect
Juxtaglomerular cell tumor (JGCT) generally affects adolescents and young adults. The patients experience symptoms related to hypertension and hypokalemia due to renin-secretion by the tumor. Grossly, the tumor is well circumscribed with fibrous capsule and the cut surface shows yellow or gray-tan color with frequent hemorrhage. Histologically, the tumor is composed of monotonous polygonal cells with entrapped normal tubules. Immunohistochemically, tumor cells exhibit a positive reactivity for renin, vimentin and CD34. Ultrastructurally, neoplastic cells contain rhomboid-shaped renin protogranules. Genetically, losses of chromosomes 9 and 11 were frequently observed. Clinically, the majority of tumors showed a benign course, but rare tumors with vascular invasion or metastasis were reported. JGCT is a curable cause of hypertensive disease if it is discovered early and surgically removed, but may cause a fatal outcome usually by a cerebrovascular attack or may cause fetal demise in pregnancy. Additionally, pathologists and urologists need to recognize that this neoplasm in most cases pursues a benign course, but aggressive forms may develop in some cases
Men's passage to fatherhood: an analysis of the contemporary relevance of transition theory
This paper presents a theoretical analysis of men's experiences of pregnancy, birth and early fatherhood. It does so using a framework of ritual transition theory and argues that despite its earlier structural-functionalist roots, transition theory remains a valuable framework, illuminating contemporary transitions across the life course. The paper discusses the historical development of transition or ritual theory and, drawing upon data generated during longitudinal ethnographic interviews with men undergoing the transition to fatherhood, analyses its relevance in understanding contemporary experiences of fatherhood
Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation
All-sky search for continuous gravitational waves from isolated neutron stars in the early O3 LIGO data
We report on an all-sky search for continuous gravitational waves in the frequency band 20-2000 Hz and with a frequency time derivative in the range of [-1.0,+0.1]×10-8 Hz/s. Such a signal could be produced by a nearby, spinning and slightly nonaxisymmetric isolated neutron star in our Galaxy. This search uses the LIGO data from the first six months of Advanced LIGO's and Advanced Virgo's third observational run, O3. No periodic gravitational wave signals are observed, and 95% confidence-level (C.L.) frequentist upper limits are placed on their strengths. The lowest upper limits on worst-case (linearly polarized) strain amplitude h0 are ∼1.7×10-25 near 200 Hz. For a circularly polarized source (most favorable orientation), the lowest upper limits are ∼6.3×10-26. These strict frequentist upper limits refer to all sky locations and the entire range of frequency derivative values. For a population-averaged ensemble of sky locations and stellar orientations, the lowest 95% C.L. upper limits on the strain amplitude are ∼1.4×10-25. These upper limits improve upon our previously published all-sky results, with the greatest improvement (factor of ∼2) seen at higher frequencies, in part because quantum squeezing has dramatically improved the detector noise level relative to the second observational run, O2. These limits are the most constraining to date over most of the parameter space searched
GWTC-2.1: Deep extended catalog of compact binary coalescences observed by LIGO and Virgo during the first half of the third observing run
The second Gravitational-Wave Transient Catalog, GWTC-2, reported on 39 compact binary coalescences observed by the Advanced LIGO and Advanced Virgo detectors between 1 April 2019 15 ∶ 00 UTC and 1 October 2019 15 ∶ 00 UTC. Here, we present GWTC-2.1, which reports on a deeper list of candidate events observed over the same period. We analyze the final version of the strain data over this period with improved calibration and better subtraction of excess noise, which has been publicly released. We employ three matched-filter search pipelines for candidate identification, and estimate the probability of astrophysical origin for each candidate event. While GWTC-2 used a false alarm rate threshold of 2 per year, we include in GWTC-2.1, 1201 candidates that pass a false alarm rate threshold of 2 per day. We calculate the source properties of a subset of 44 high-significance candidates that have a probability of astrophysical origin greater than 0.5. Of these candidates, 36 have been reported in GWTC-2. We also calculate updated source properties for all binary black hole events previously reported in GWTC-1. If the eight additional high-significance candidates presented here are astrophysical, the mass range of events that are unambiguously identified as binary black holes (both objects ≥ 3 M⊙ ) is increased compared to GWTC-2, with total masses from ∼ 14 M ⊙ for GW190924_021846 to ∼ 182 M⊙ for GW190426_190642. Source properties calculated using our default prior suggest that the primary components of two new candidate events (GW190403_051519 and GW190426_190642) fall in the mass gap predicted by pair-instability supernova theory. We also expand the population of binaries with significantly asymmetric mass ratios reported in GWTC-2 by an additional two events (the mass ratio is less than 0.65 and 0.44 at 90% probability for GW190403_051519 and GW190917_114630 respectively), and find that two of the eight new events have effective inspiral spins χeff > 0 (at 90% credibility), while no binary is consistent with χeff < 0 at the same significance. We provide updated estimates for rates of binary black hole and binary neutron star coalescence in the local Universe
All-sky, all-frequency directional search for persistent gravitational waves from Advanced LIGO’s and Advanced Virgo’s first three observing runs
We present the first results from an all-sky all-frequency (ASAF) search for
an anisotropic stochastic gravitational-wave background using the data from the
first three observing runs of the Advanced LIGO and Advanced Virgo detectors.
Upper limit maps on broadband anisotropies of a persistent stochastic
background were published for all observing runs of the LIGO-Virgo detectors.
However, a broadband analysis is likely to miss narrowband signals as the
signal-to-noise ratio of a narrowband signal can be significantly reduced when
combined with detector output from other frequencies. Data folding and the
computationally efficient analysis pipeline, {\tt PyStoch}, enable us to
perform the radiometer map-making at every frequency bin. We perform the search
at 3072 {\tt{HEALPix}} equal area pixels uniformly tiling the sky and in every
frequency bin of width ~Hz in the range ~Hz, except for bins
that are likely to contain instrumental artefacts and hence are notched. We do
not find any statistically significant evidence for the existence of narrowband
gravitational-wave signals in the analyzed frequency bins. Therefore, we place
confidence upper limits on the gravitational-wave strain for each
pixel-frequency pair, the limits are in the range . In addition, we outline a method to identify candidate
pixel-frequency pairs that could be followed up by a more sensitive (and
potentially computationally expensive) search, e.g., a matched-filtering-based
analysis, to look for fainter nearly monochromatic coherent signals. The ASAF
analysis is inherently independent of models describing any spectral or spatial
distribution of power. We demonstrate that the ASAF results can be
appropriately combined over frequencies and sky directions to successfully
recover the broadband directional and isotropic results
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