2,381 research outputs found
Ocorrência de Anastrepha fraterculus (Diptera:Tephritidae) em butiazeiro (Butia odorata) na região de Pelotas, RS.
O objetivo do trabalho foi registrar a presença de dípteros da família Tephritidae em pomares na área experimental da Embrapa Clima Temperado, em Pelotas, RS
SUR1 Receptor Interaction with Hesperidin and Linarin Predicts Possible Mechanisms of Action of Valeriana officinalis in Parkinson.
Parkinson's disease (PD) is one of the most common neurodegenerative disorders. A theoretical approach of our previous experiments reporting the cytoprotective effects of the Valeriana officinalis compounds extract for PD is suggested. In addiction to considering the PD as a result of mitochondrial metabolic imbalance and oxidative stress, such as in our previous in vitro model of rotenone, in the present manuscript we added a genomic approach to evaluate the possible underlying mechanisms of the effect of the plant extract. Microarray of substantia nigra (SN) genome obtained from Allen Brain Institute was analyzed using gene set enrichment analysis to build a network of hub genes implicated in PD. Proteins transcribed from hub genes and their ligands selected by search ensemble approach algorithm were subjected to molecular docking studies, as well as 20 ns Molecular Dynamics (MD) using a Molecular Mechanic Poison/Boltzman Surface Area (MMPBSA) protocol. Our results bring a new approach to Valeriana officinalis extract, and suggest that hesperidin, and probably linarin are able to relieve effects of oxidative stress during ATP depletion due to its ability to binding SUR1. In addition, the key role of valerenic acid and apigenin is possibly related to prevent cortical hyperexcitation by inducing neuronal cells from SN to release GABA on brain stem. Thus, under hyperexcitability, oxidative stress, asphyxia and/or ATP depletion, Valeriana officinalis may trigger different mechanisms to provide neuronal cell protection.Fil: Santos, Gesivaldo. Universidade Estadual do Sudoeste da Bahia; BrasilFil: Giraldez Alvarez, Lisandro Diego. Universidade Estadual do Sudoeste da Bahia; BrasilFil: Ávila Rodriguez, Marco. Pontificia Universidad Javeriana; ColombiaFil: Capani, Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; ArgentinaFil: Galembeck, Eduardo. Universidade Estadual de Campinas; BrasilFil: Gôes Neto, Aristóteles. Universidade Estadual de Feira de Santana; BrasilFil: Barreto, George E.. Pontificia Universidad Javeriana; ColombiaFil: Andrade, Bruno. Universidade Estadual do Sudoeste da Bahia; Brasi
Coulomb matrix elements of bilayers of confined charge carriers with arbitrary spatial separation
We describe a practical procedure to calculate the Coulomb matrix elements of
2D spatially separated and confined charge carriers, which are needed for
detailed theoretical descriptions of important condensed matter finite systems.
We derive an analytical expression, for arbitrary separations, in terms of a
single infinite series and apply a u-type Levin transform in order to
accelerate the resulting infinite series. This procedure has proven to be
efficient and accurate. Direct consequences concerning the functional
dependence of the matrix elements on the separation distance, transition
amplitudes and the diagonalization of a single electron-hole pair in vertically
stacked parabolic quantum dots are presented.Comment: 8 page
Bond-disordered spin systems: Theory and application to doped high-Tc compounds
We examine the stability of magnetic order in a classical Heisenberg model
with quenched random exchange couplings. This system represents the spin
degrees of freedom in high- compounds with immobile dopants.
Starting from a replica representation of the nonlinear -model, we
perform a renormalization-group analysis. The importance of cumulants of the
disorder distribution to arbitrarily high orders necessitates a functional
renormalization scheme. From the renormalization flow equations we determine
the magnetic correlation length numerically as a function of the impurity
concentration and of temperature. From our analysis follows that
two-dimensional layers can be magnetically ordered for arbitrarily strong but
sufficiently diluted defects. We further consider the dimensional crossover in
a stack of weakly coupled layers. The resulting phase diagram is compared with
experimental data for LaSrCuO.Comment: 12 pages, 5 figure
Intake and digestibility of river buffalo steers (Bubalus bubalis) fed different levels of palm kernel cake: effect of diet neutral detergent fiber, digestible energy, crude protein and extract ether.
Proceeding of World Buffalo Congress, 9., 2010, Buenos Aires
Stability of Terrestrial Planets in the Habitable Zone of Gl 777 A, HD 72659, Gl 614, 47 Uma and HD 4208
We have undertaken a thorough dynamical investigation of five extrasolar
planetary systems using extensive numerical experiments. The systems Gl 777 A,
HD 72659, Gl 614, 47 Uma and HD 4208 were examined concerning the question of
whether they could host terrestrial like planets in their habitable zones
(=HZ). First we investigated the mean motion resonances between fictitious
terrestrial planets and the existing gas giants in these five extrasolar
systems. Then a fine grid of initial conditions for a potential terrestrial
planet within the HZ was chosen for each system, from which the stability of
orbits was then assessed by direct integrations over a time interval of 1
million years. The computations were carried out using a Lie-series integration
method with an adaptive step size control. This integration method achieves
machine precision accuracy in a highly efficient and robust way, requiring no
special adjustments when the orbits have large eccentricities. The stability of
orbits was examined with a determination of the Renyi entropy, estimated from
recurrence plots, and with a more straight forward method based on the maximum
eccentricity achieved by the planet over the 1 million year integration.
Additionally, the eccentricity is an indication of the habitability of a
terrestrial planet in the HZ; any value of e>0.2 produces a significant
temperature difference on a planet's surface between apoapse and periapse. The
results for possible stable orbits for terrestrial planets in habitable zones
for the five systems are summarized as follows: for Gl 777 A nearly the entire
HZ is stable, for 47 Uma, HD 72659 and HD 4208 terrestrial planets can survive
for a sufficiently long time, while for Gl 614 our results exclude terrestrial
planets moving in stable orbits within the HZ.Comment: 14 pages, 18 figures submitted to A&
Highlights from the Pierre Auger Observatory
The Pierre Auger Observatory is the world's largest cosmic ray observatory.
Our current exposure reaches nearly 40,000 km str and provides us with an
unprecedented quality data set. The performance and stability of the detectors
and their enhancements are described. Data analyses have led to a number of
major breakthroughs. Among these we discuss the energy spectrum and the
searches for large-scale anisotropies. We present analyses of our X
data and show how it can be interpreted in terms of mass composition. We also
describe some new analyses that extract mass sensitive parameters from the 100%
duty cycle SD data. A coherent interpretation of all these recent results opens
new directions. The consequences regarding the cosmic ray composition and the
properties of UHECR sources are briefly discussed.Comment: 9 pages, 12 figures, talk given at the 33rd International Cosmic Ray
Conference, Rio de Janeiro 201
The Pierre Auger Observatory III: Other Astrophysical Observations
Astrophysical observations of ultra-high-energy cosmic rays with the Pierre
Auger ObservatoryComment: Contributions to the 32nd International Cosmic Ray Conference,
Beijing, China, August 201
Multi-resolution anisotropy studies of ultrahigh-energy cosmic rays detected at the Pierre Auger Observatory
We report a multi-resolution search for anisotropies in the arrival
directions of cosmic rays detected at the Pierre Auger Observatory with local
zenith angles up to and energies in excess of 4 EeV ( eV). This search is conducted by measuring the angular power spectrum
and performing a needlet wavelet analysis in two independent energy ranges.
Both analyses are complementary since the angular power spectrum achieves a
better performance in identifying large-scale patterns while the needlet
wavelet analysis, considering the parameters used in this work, presents a
higher efficiency in detecting smaller-scale anisotropies, potentially
providing directional information on any observed anisotropies. No deviation
from isotropy is observed on any angular scale in the energy range between 4
and 8 EeV. Above 8 EeV, an indication for a dipole moment is captured; while no
other deviation from isotropy is observed for moments beyond the dipole one.
The corresponding -values obtained after accounting for searches blindly
performed at several angular scales, are in the case of
the angular power spectrum, and in the case of the needlet
analysis. While these results are consistent with previous reports making use
of the same data set, they provide extensions of the previous works through the
thorough scans of the angular scales.Comment: Published version. Added journal reference and DOI. Added Report
Numbe
Ultrahigh-energy neutrino follow-up of Gravitational Wave events GW150914 and GW151226 with the Pierre Auger Observatory
On September 14, 2015 the Advanced LIGO detectors observed their first
gravitational-wave (GW) transient GW150914. This was followed by a second GW
event observed on December 26, 2015. Both events were inferred to have arisen
from the merger of black holes in binary systems. Such a system may emit
neutrinos if there are magnetic fields and disk debris remaining from the
formation of the two black holes. With the surface detector array of the Pierre
Auger Observatory we can search for neutrinos with energy above 100 PeV from
point-like sources across the sky with equatorial declination from about -65
deg. to +60 deg., and in particular from a fraction of the 90% confidence-level
(CL) inferred positions in the sky of GW150914 and GW151226. A targeted search
for highly-inclined extensive air showers, produced either by interactions of
downward-going neutrinos of all flavors in the atmosphere or by the decays of
tau leptons originating from tau-neutrino interactions in the Earth's crust
(Earth-skimming neutrinos), yielded no candidates in the Auger data collected
within s around or 1 day after the coordinated universal time (UTC)
of GW150914 and GW151226, as well as in the same search periods relative to the
UTC time of the GW candidate event LVT151012. From the non-observation we
constrain the amount of energy radiated in ultrahigh-energy neutrinos from such
remarkable events.Comment: Published version. Added journal reference and DOI. Added Report
Numbe
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