136 research outputs found

    ‘A Mirror for Fellow-Citizens’: Cicero’s Proto-Transformational Leadership Ideal of the Rector Rei Publicae

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    In this article, I situate Cicero’s discussion of the rector rei publicae and orator perfectus in the De republica and De oratore in the context of James MacGregor Burns’s theory of the transformational leadership in his influential 1978 Leadership. I then consider how Cicero’s rector rei publicae would exhibit leadership behaviors of the Full Range Leadership Model, a popular operationalization of transformational leadership theory. Throughout, I also consider the limitations of applying transformational leadership as an interpretive frame for an ancient Roman leader such as Cicero. Cicero’s vision, I contend, can only succeed in being proto-transformational. The result of this analysis is a paper that is of interest to both scholars and students of the Ancient Mediterranean and contemporary Leadership Studies. At the end of this essay, I remark on the continued relevance of the rector-ideal, especially in conversation with another noteworthy philosophical practitioner of leadership: Martin Luther King, Jr

    Scipio’s Rome and Critias’ Athens: Utopian Mythmaking in Cicero’s De Republica and Plato’s Timaeus

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    Scholarly debate on the relationship between Cicero’s De republica (On the Republic) and De Legibus (On the Laws) and the thought of Plato tends to focus on the supposed congruities or incongruities of the De republica and De legibus with Plato’s own Republic and Laws. Still, Plato’s discussion of ideal constitutions is not constrained to the Republic and Laws. In this essay I propose that we look to another of Plato’s dialogues for fruitful comparison: the Timaeus-Critias duology. In this essay I bring these two texts into substantive dialogue to illuminate mysterious features of both. Sketched in these complementary passages, I think, is an outline for a particular kind of approach to political theory, one proposed as novel by Cicero’s Laelius, but, as this essay hopes to show, with an interesting forerunner in Plato. I’ve called this approach ‘retrospective ideal political philosophy’ (RIPP). I end my essay with a few prospective theoretical notes on how this approach binds these two texts together

    ‘Conserere Sapientiam’, To Engage in Wisdom: The Rhetoric of Philosophical Debate and the Speech of Caecilius in Minucius Felix’s Octavius

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    Here I will elucidate both the rhetorical and philosophical significance of the introduction to Minucius Felix’s Octavius—in effect, to give voice to what Minucius Felix hoped to do in having Caecilius and Octavius conserere sapientiam (‘engage in wisdom’). I draw special attention to the introduction to the dialogue because (i) Minucius’ rhetorical care in establishing an appropriate otium (in other words, a locus amoenus) for his dialogue participants has been underappreciated (ii) because Caecilius’ arguments have, in general, been given short-shrift, and, (iii) because the view that the introductory parts should, instead, be read with suspicion has found a recent prominent voice in an influential recent article (Powell 2007)

    Ultrasonic Monitoring of Recrystallization Textures in Aluminum

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    The present paper is an attempt to use ultrasonic velocity measurements to characterize the texture of an aluminum-magnesium alloy (Al 5xxx) and to compare the results with orientation imaging microscopy (OIM) results. The results are characterized in terms of three orientation distribution coefficients (ODC’s), W400, W420, and W440, each of which describes a particular forming anisotropy, and each of which has significant impact on the final products

    Lineage-specific evolution of the vertebrate Otopetrin gene family revealed by comparative genomic analyses

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    Background: Mutations in the Otopetrin 1 gene (Otop1) in mice and fish produce an unusual bilateral vestibular pathology that involves the absence of otoconia without hearing impairment. The encoded protein, Otop1, is the only functionally characterized member of the Otopetrin Domain Protein (ODP) family; the extended sequence and structural preservation of ODP proteins in metazoans suggest a conserved functional role. Here, we use the tools of sequence-and cytogenetic-based comparative genomics to study the Otop1 and the Otop2-Otop3 genes and to establish their genomic context in 25 vertebrates. We extend our evolutionary study to include the gene mutated in Usher syndrome (USH) subtype 1G (Ush1g), both because of the head-to-tail clustering of Ush1g with Otop2 and because Otop1 and Ush1g mutations result in inner ear phenotypes. Results: We established that OTOP1 is the boundary gene of an inversion polymorphism on human chromosome 4p16 that originated in the common human-chimpanzee lineage more than 6 million years ago. Other lineage-specific evolutionary events included a three-fold expansion of the Otop genes in Xenopus tropicalis and of Ush1g in teleostei fish. The tight physical linkage between Otop2 and Ush1g is conserved in all vertebrates. To further understand the functional organization of the Ushg1-Otop2 locus, we deduced a putative map of binding sites for CCCTC-binding factor (CTCF), a mammalian insulator transcription factor, from genome-wide chromatin immunoprecipitation-sequencing (ChIP-seq) data in mouse and human embryonic stem (ES) cells combined with detection of CTCF-binding motifs. Conclusions: The results presented here clarify the evolutionary history of the vertebrate Otop and Ush1g families, and establish a framework for studying the possible interaction(s) of Ush1g and Otop in developmental pathways

    Relative Burden of Large CNVs on a Range of Neurodevelopmental Phenotypes

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    While numerous studies have implicated copy number variants (CNVs) in a range of neurological phenotypes, the impact relative to disease severity has been difficult to ascertain due to small sample sizes, lack of phenotypic details, and heterogeneity in platforms used for discovery. Using a customized microarray enriched for genomic hotspots, we assayed for large CNVs among 1,227 individuals with various neurological deficits including dyslexia (376), sporadic autism (350), and intellectual disability (ID) (501), as well as 337 controls. We show that the frequency of large CNVs (>1 Mbp) is significantly greater for ID–associated phenotypes compared to autism (p = 9.58×10−11, odds ratio = 4.59), dyslexia (p = 3.81×10−18, odds ratio = 14.45), or controls (p = 2.75×10−17, odds ratio = 13.71). There is a striking difference in the frequency of rare CNVs (>50 kbp) in autism (10%, p = 2.4×10−6, odds ratio = 6) or ID (16%, p = 3.55×10−12, odds ratio = 10) compared to dyslexia (2%) with essentially no difference in large CNV burden among dyslexia patients compared to controls. Rare CNVs were more likely to arise de novo (64%) in ID when compared to autism (40%) or dyslexia (0%). We observed a significantly increased large CNV burden in individuals with ID and multiple congenital anomalies (MCA) compared to ID alone (p = 0.001, odds ratio = 2.54). Our data suggest that large CNV burden positively correlates with the severity of childhood disability: ID with MCA being most severely affected and dyslexics being indistinguishable from controls. When autism without ID was considered separately, the increase in CNV burden was modest compared to controls (p = 0.07, odds ratio = 2.33)
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