960 research outputs found
The Causation of Design Error in the Construction Industry: A Multistakeholder Perspective
A seemingly minor design error can have significant repercussions in a construction project, leading to serious safety and quality consequences, cost overrun, and delays. This error can have a lasting impact, potentially affecting usability and safety during the operational stage of the completed facility. Despite these consequences, there is limited research on which stakeholders contribute more significantly to design errors. Furthermore, there is a disconnection in understanding among stakeholders about the causes of design errors. To address the knowledge gap, this research aimed to identify the critical causes of design errors from a multistakeholder perspective. Empirical survey data were collected from 243 design professionals (e.g., architects, structural designers, and water supply and drainage designers) across various stakeholders (e.g., clients, design companies, and construction companies) in the Chinese construction industry. Descriptive and structural equation modeling (SEM) analyses reveal that contrary to common understanding, clients and geological surveying companies are the major stakeholders responsible for design errors in construction projects. The major factors leading to design errors are design input information error, unreasonable intervention on design, noncompliance with standard requirements, and error in site geological survey document. In contrast, concurrent design and construction requirements and poor working conditions are the least influential factors. Design professionals, regardless of their stakeholder groups, shared similar views on the causes of design errors. This research is among the first to uncover the causes of design errors on construction projects from a multistakeholder perspective. The findings offer valuable insights for stakeholders to improve design quality in the Chinese construction industry and other countries with similar environments
Evidence for an excess of B -> D(*) Tau Nu decays
Based on the full BaBar data sample, we report improved measurements of the
ratios R(D(*)) = B(B -> D(*) Tau Nu)/B(B -> D(*) l Nu), where l is either e or
mu. These ratios are sensitive to new physics contributions in the form of a
charged Higgs boson. We measure R(D) = 0.440 +- 0.058 +- 0.042 and R(D*) =
0.332 +- 0.024 +- 0.018, which exceed the Standard Model expectations by 2.0
sigma and 2.7 sigma, respectively. Taken together, our results disagree with
these expectations at the 3.4 sigma level. This excess cannot be explained by a
charged Higgs boson in the type II two-Higgs-doublet model. We also report the
observation of the decay B -> D Tau Nu, with a significance of 6.8 sigma.Comment: Expanded section on systematics, text corrections, improved the
format of Figure 2 and included the effect of the change of the Tau
polarization due to the charged Higg
Performance of the CMS Cathode Strip Chambers with Cosmic Rays
The Cathode Strip Chambers (CSCs) constitute the primary muon tracking device
in the CMS endcaps. Their performance has been evaluated using data taken
during a cosmic ray run in fall 2008. Measured noise levels are low, with the
number of noisy channels well below 1%. Coordinate resolution was measured for
all types of chambers, and fall in the range 47 microns to 243 microns. The
efficiencies for local charged track triggers, for hit and for segments
reconstruction were measured, and are above 99%. The timing resolution per
layer is approximately 5 ns
Fumarate Analogs Act as Allosteric Inhibitors of the Human Mitochondrial NAD(P)+-Dependent Malic Enzyme
Human mitochondrial NAD(P)+-dependent malic enzyme (m-NAD(P)-ME) is allosterically activated by the four-carbon trans dicarboxylic acid, fumarate. Previous studies have suggested that the dicarboxylic acid in a trans conformation around the carbon-carbon double bond is required for the allosteric activation of the enzyme. In this paper, the allosteric effects of fumarate analogs on m-NAD(P)-ME are investigated. Two fumarate-insensitive mutants, m-NAD(P)-ME_R67A/R91A and m-NAD(P)-ME_K57S/E59N/K73E/D102S, as well as c-NADP-ME, were used as the negative controls. Among these analogs, mesaconate, trans-aconitate, monomethyl fumarate and monoethyl fumarate were allosteric activators of the enzyme, while oxaloacetate, diethyl oxalacetate, and dimethyl fumarate were found to be allosteric inhibitors of human m-NAD(P)-ME. The IC50 value for diethyl oxalacetate was approximately 2.5 mM. This paper suggests that the allosteric inhibitors may impede the conformational change from open form to closed form and therefore inhibit m-NAD(P)-ME enzyme activity
Brief Report: A Cross-Sectional Study of Anxiety Levels and Concerns of Chinese Families of Children With Special Educational Needs and Disabilities Post-first-wave of COVID-19
The COVID-19 pandemic has a multifaceted impact on mental health due to ill health, restrictions and lockdowns, and loss of employment and institutional support. COVID-19 may disproportionally impact families with special educational needs and disabilities (SEND) due to the already higher prevalence of mental health conditions in children with SEND and their parents. Therefore, it is essential to determine the short-term impact of the pandemic on the mental health of families with SEND in order to identify their ongoing health support needs. The current study aims to examine the anxiety level and concerns of children with SEND and their parents living in China. The sample consisted of 271 parents of children with SEND aged between 6 and 17 years (M age = 8.37; SD age = 2.76). Parents completed an online survey between 10 April to 8 June 2020. Both child and parental anxiety levels and various concerns increased after the initial wave of COVID-19 when compared with retrospective pre-COVID-19 levels. Parental anxiety and concern levels were significantly higher for those living in rural areas compared to urban areas. In addition, parental and child anxiety and concern levels were significantly correlated with each other. Parental anxiety at the lowest level made a unique and significant statistical contribution to children's anxiety levels. The implications of the study findings are discussed
Search for the decay modes D^0 → e^+e^-, D^0 → μ^+μ^-, and D^0 → e^±μ∓
We present searches for the rare decay modes D^0→e^+e^-, D^0→μ^+μ^-, and D^0→e^±μ^∓ in continuum e^+e^-→cc events recorded by the BABAR detector in a data sample that corresponds to an integrated luminosity of 468 fb^(-1). These decays are highly Glashow–Iliopoulos–Maiani suppressed but may be enhanced in several extensions of the standard model. Our observed event yields are consistent with the expected backgrounds. An excess is seen in the D^0→μ^+μ^- channel, although the observed yield is consistent with an upward background fluctuation at the 5% level. Using the Feldman–Cousins method, we set the following 90% confidence level intervals on the branching fractions: B(D^0→e^+e^-)<1.7×10^(-7), B(D^0→μ^+μ^-) within [0.6,8.1]×10^(-7), and B(D^0→e^±μ^∓)<3.3×10^(-7)
Fog computing security: a review of current applications and security solutions
Fog computing is a new paradigm that extends the Cloud platform model by providing computing resources on the edges of a network. It can be described as a cloud-like platform having similar data, computation, storage and application services, but is fundamentally different in that it is decentralized. In addition, Fog systems are capable of processing large amounts of data locally, operate on-premise, are fully portable, and can be installed on heterogeneous hardware. These features make the Fog platform highly suitable for time and location-sensitive applications. For example, Internet of Things (IoT) devices are required to quickly process a large amount of data. This wide range of functionality driven applications intensifies many security issues regarding data, virtualization, segregation, network, malware and monitoring. This paper surveys existing literature on Fog computing applications to identify common security gaps. Similar technologies like Edge computing, Cloudlets and Micro-data centres have also been included to provide a holistic review process. The majority of Fog applications are motivated by the desire for functionality and end-user requirements, while the security aspects are often ignored or considered as an afterthought. This paper also determines the impact of those security issues and possible solutions, providing future security-relevant directions to those responsible for designing, developing, and maintaining Fog systems
Low level constraints on dynamic contour path integration
Contour integration is a fundamental visual process. The constraints on integrating
discrete contour elements and the associated neural mechanisms have typically been
investigated using static contour paths. However, in our dynamic natural environment
objects and scenes vary over space and time. With the aim of investigating the
parameters affecting spatiotemporal contour path integration, we measured human
contrast detection performance of a briefly presented foveal target embedded in
dynamic collinear stimulus sequences (comprising five short 'predictor' bars appearing
consecutively towards the fovea, followed by the 'target' bar) in four experiments. The
data showed that participants' target detection performance was relatively unchanged
when individual contour elements were separated by up to 2° spatial gap or 200ms
temporal gap. Randomising the luminance contrast or colour of the predictors, on the
other hand, had similar detrimental effect on grouping dynamic contour path and
subsequent target detection performance. Randomising the orientation of the
predictors reduced target detection performance greater than introducing misalignment
relative to the contour path. The results suggest that the visual system integrates
dynamic path elements to bias target detection even when the continuity of path is
disrupted in terms of spatial (2°), temporal (200ms), colour (over 10 colours) and
luminance (-25% to 25%) information. We discuss how the findings can be largely
reconciled within the functioning of V1 horizontal connections
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