Secure Biomedical Document Protection Framework to Ensure Privacy Through Blockchain

In the recent health care era, biomedical documents play a crucial role, and they contain much evidence-based documentation associated with many stakeholders data. Protecting those confidential research documents is more difficult and effective, and a significant process in the medical-based research domain. Those bio-documentation related to health care and other relevant community-valued data are suggested by medical professionals and processed. Many traditional security mechanisms such as akteonline and Health Insurance Portability and Accountability Act (HIPAA) are used to protect the biomedical documents as they consider the problem of non-repudiation and data integrity related to the retrieval and storage of documents. Thus, there is a need for a comprehensive framework that improves protection in terms of cost and response time related to biomedical documents. In this research work, blockchain-based biomedical document protection framework (BBDPF) is proposed, which includes blockchain-based biomedical data protection (BBDP) and blockchain-based biomedical data retrieval (BBDR) algorithms. BBDP and BBDR algorithms provide consistency on the data to prevent data modification and interception of confidential data with proper data validation. Both the algorithms have strong cryptographic mechanisms to withstand post-quantum security risks, ensuring the integrity of biomedical document retrieval and non-deny of data retrieval transactions. In the performance analysis, Ethereum blockchain infrastructure is deployed BBDPF and smart contracts using Solidity language. In the performance analysis, request time and searching time are determined based on the number of request to ensure data integrity, non-repudiation, and smart contracts for the proposed hybrid model as it gets increased gradually. A modified prototype is built with a web-based interface to prove the concept and evaluate the proposed framework. The experimental results revealed that the proposed framework renders data integrity, non-repudiation, and support for smart contracts with Query Notary Service, MedRec, MedShare, and Medlock

2,4,6,8-Tetra­kis(4-chloro­phen­yl)-3,7-diaza­bicyclo­[3.3.1]nonan-9-one O-benzyl­oxime acetone monosolvate

In the title compound, C38H31Cl4N3O·C3H6O, the 3,7-diaza-bicycle exists in a chair–boat conformation. The 4-chloro­phenyl groups attached to the chair form are equatorially oriented at an angle of 18.15 (3)° with respect to each other, whereas the 4-chloro­phenyl groups attached to the boat form are oriented at an angle of 32.64 (3)°. In the crystal, mol­ecules are linked by N—H⋯π and C—H⋯O inter­actions

Synthesis and Characterization of Silver and Gold Nanoparticles Using Aqueous Extract of Seaweed, Turbinaria conoides,

Silver and gold nanoparticles were synthesized using an aqueous extract of the seaweed Turbinaria conoides and their antibiofilm activity against marine biofilm forming bacteria is reported here. The UV-Vis spectra showed the characteristics SPR absorption band for Ag NPs at 421 and for Au NPs at 538 nm. Further, the synthesized nanoparticles were characterized using FT-IR, XRD, FESEM, EDX, and HRTEM analysis. Spherical and triangular nanostructures of the Ag and Au nanoparticles were observed between the size ranges of 2–17 nm and 2–19 nm, respectively. The synthesized Ag NPs are efficient in controlling the bacterial biofilm formation; however, Au NPs did not show any remarkable antibiofilm activity. The maximum zone of inhibition was recorded against E. coli (17.6±0.42 mm), followed by Salmonella sp., S. liquefaciens, and A. hydrophila. The macrotube dilution method inferred the MIC (20–40 µL mL−1) and MBC (40–60 µL mL−1) of Ag NPs. The CLSM images clearly showed the weak adherence and disintegrating biofilm formation of marine biofilm bacterial strains treated with Ag NPs. The Artemia cytotoxicity assay recorded the LC50 value of 88.914±5.04 µL mL−1. Thus the present study proved the efficiency of Ag NPs as a potent antimicrofouling agent and became the future perspective for the possible usage in the biofouling related issues in the aquaculture installations and other marine systems

An optimal multitier resource allocation of cloud RAN in 5G using machine learning

The networks are evolving drastically since last few years in order to meetuser requirements. For example, the 5G is offering most of the available spec-trum under one umbrella. In this work, we will address the resource allocationproblem in fifth-generation (5G) networks, to be exact in the Cloud Radio AccessNetworks (C-RANs). The radio access network mechanisms involve multiplenetwork topologies that are isolated based on the spectrum bands and it shouldbe enhanced with numerous access technology in the deployment of 5G net-work. The C-RAN is one of the optimal technique to combine all the availablespectral bands. However, existing C-RAN mechanisms lacks the intelligence per-spective on choosing the spectral bands. Thus, C-RAN mechanism requires anadvanced tool to identify network topology to allocate the network resources forsubstantial traffic volumes. Therefore, there is a need to propose a frameworkthat handles spectral resources based on user requirements and network behav-ior. In this work, we introduced a new C-RAN architecture modified as multitierHeterogeneous Cloud Radio Access Networks in a 5G environment. This archi-tecture handles spectral resources efficiently. Based on the simulation analysis,the proposed multitier H-CRAN architecture with improved control unit innetwork management perspective enables augmented granularity, end-to-endoptimization, and guaranteed quality of service by 15 percentages over theexisting system

Temporal and Spatial Variations of the Solar Radiation Observed in Singapore

AbstractMeteorological phenomena, such as fast moving clouds, cause rapid changes in the terrestrial direct beam radiation. This introduces transients in both the temporal and spatial measurements of global horizontal radiation. These transients in radiation affect the performance of solar energy conversion systems (PV, CPV systems and solar thermal applications) and cause their output power to vary widely. Thus, to properly understand the dynamic fluctuations observed in the output energies of large solar farms and PV arrays, it becomes necessary to perform a high-resolution temporal and spatial measurement of solar radiation. It turns out that performing such high-resolution measurements is often cost-prohibitive. Studies were conducted to understand and quantify the temporal and the spatial variations of direct beam, diffused and global horizontal radiation. These studies were based on the radiation data collected at the Nanyang Technological University, Singapore at a time interval of 1 s. It was inferred from these studies that the temporal variations in the instantaneous diffuse radiation are minimum and there was little spatial variations seen across distances of 500 m. The transients observed in global horizontal radiation are predominantly restricted to the changes occurring in the direct beam component of the solar radiation. Based on these inferences, a simple and costeffective method is proposed that would permit accurate large scale localised high-resolution measurements of individual components of the solar radiation

A novel method to overcome the shortcomings of turbocharging a single cylinder diesel engine

Single-cylinder diesel engines are generally not turbocharged because of highly pulsating exhaust gas flow, resulting in increased speed fluctuations and reduced turbine performance. In the present work, a novel and simple method is proposed wherein an exhaust plenum is placed before the turbine to reduce the flow fluctuations. A production light-duty naturally aspirated (NA) diesel engine modified into the turbocharged version was incorporated with an exhaust plenum. Steady-state experiments were performed with the base naturally aspirated engine, the turbocharged version without an exhaust plenum (conventional pulse turbocharging), and the turbocharged version with the exhaust plenum. The present work attempts to establish the limitations of conventional pulse turbocharging in a single-cylinder diesel engine unavailable in the existing literature. Though the conventional pulse turbocharged version could deliver a boost pressure of about 2 bar (absolute), a brake power reduction of 40% and the associated drop in brake mean effective pressure was observed compared to the base NA engine due to high exhaust back pressures. The pumping work was four times higher in conventional pulse turbocharging than the NA engine, thus reducing the performance. After validating the simulation models, a one-dimensional simulation tool was used to evaluate the effect of incorporating exhaust plenum before the turbine. Simulated results predicted the brake power output within a 3% error for the NA and plenum turbocharging configurations. An optimal plenum volume was arrived at using the validated simulation model. Subsequent experiments on the turbocharged engine with the plenum in place showed a significant improvement in the engine performance and reduced exhaust emissions compared to the NA version. Brake power output was enhanced by 25%, which indicated improved thermal efficiency of 2%. Compared to the NA version, the soot, carbon monoxide (CO) and unburned hydrocarbon HC emissions were reduced by 93%, 88%, and 53%, respectively. However, an increase in oxides of nitrogen (NOx) emissions was seen, which can be controlled with suitable mitigation methods taking advantage of the significantly lower soot levels. Thus, the proposed method of placing an exhaust plenum before the turbine makes turbocharging viable on single-cylinder diesel engines with performance improvement and emission reduction when suitable NOx mitigation measures are adopted. </jats:p