Production and properties of thin film materials sol-gel by method based on TiO[2]-MxOy, where M-Ni, Cu, Zn

The physical-chemical, morphological, and structural properties of thin-film TiO[2]-MxOy obtained by sol-gel method were investigated. Titanium sol is formed by controlled hydrolysis of tetrabutoxy titanium in acidic media. The effect of synthesis and calcination temperature on the phase, crystal size was studied using Xray phase analysis (XRD), scanning electron microscopy (SEM). XRD observations confirmed the nanocrystalline nature of TiO[2]

Influence of nanosecond microwave pulses on the level of cortycosterone

This article describes experimental data on 30 nonlinear rats exposed to microwave radiation at frequencies 8, 13, 16 and 22 pulse per second (pps) in order to record corticosteron changes as an indicator of stress in rodent blood. During the experiment, it was found that the most significant increase is observed at frequencies 13, 16 pps and at 22, 8 pps a decrease and a slight increase in corticosteron were recorded respectively

Parametrization of dark energy equation of state Revisited

A comparative study of various parametrizations of the dark energy equation of state is made. Astrophysical constraints from LSS, CMB and BBN are laid down to test the physical viability and cosmological compatibility of these parametrizations. A critical evaluation of the 4-index parametrizations reveals that Hannestad-M\"{o}rtsell as well as Lee parametrizations are simple and transparent in probing the evolution of the dark energy during the expansion history of the universe and they satisfy the LSS, CMB and BBN constraints on the dark energy density parameter for the best fit values.Comment: 11 page

A large geometric distortion in the first photointermediate of rhodopsin, determined by double-quantum solid-state NMR

Double-quantum magic-angle-spinning NMR experiments were performed on 11,12-C-13(2)-retinylidene-rhodopsin under illumination at low temperature, in order to characterize torsional angle changes at the C11-C12 photoisomerization site. The sample was illuminated in the NMR rotor at low temperature (similar to 120 K) in order to trap the primary photointermediate, bathorhodopsin. The NMR data are consistent with a strong torsional twist of the HCCH moiety at the isomerization site. Although the HCCH torsional twist was determined to be at least 40A degrees, it was not possible to quantify it more closely. The presence of a strong twist is in agreement with previous Raman observations. The energetic implications of this geometric distortion are discussed

Anti-plasmodial polyvalent interactions in Artemisia annua L. aqueous extract – possible synergistic and resistance mechanisms

Artemisia annua hot water infusion (tea) has been used in in vitro experiments against P. falciparum malaria parasites to test potency relative to equivalent pure artemisinin. High performance liquid chromatography (HPLC) and mass spectrometric analyses were employed to determine the metabolite profile of tea including the concentrations of artemisinin (47.5±0.8 mg L-1), dihydroartemisinic acid (70.0±0.3 mg L-1), arteannuin B (1.3±0.0 mg L-1), isovitexin (105.0±7.2 mg L-1) and a range of polyphenolic acids. The tea extract, purified compounds from the extract, and the combination of artemisinin with the purified compounds were tested against chloroquine sensitive and chloroquine resistant strains of P. falciparum using the DNA-intercalative SYBR Green I assay. The results of these in vitro tests and of isobologram analyses of combination effects showed mild to strong antagonistic interactions between artemisinin and the compounds (9-epi-artemisinin and artemisitene) extracted from A. annua with significant (IC50 <1 μM) anti-plasmodial activities for the combination range evaluated. Mono-caffeoylquinic acids, tri-caffeoylquinic acid, artemisinic acid and arteannuin B showed additive interaction while rosmarinic acid showed synergistic interaction with artemisinin in the chloroquine sensitive strain at a combination ratio of 1:3 (artemisinin to purified compound). In the chloroquine resistant parasite, using the same ratio, these compounds strongly antagonised artemisinin anti-plasmodial activity with the exception of arteannuin B, which was synergistic. This result would suggest a mechanism targeting parasite resistance defenses for arteannuin B’s potentiation of artemisinin